Protein Alignment rpk and Asic3

DIOPT Version :9

• Sequence 1: NP_001246909.1
• Gene: rpk / 40580
• FlyBaseID: FBgn0022981
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_006535700.1
• Gene: Asic3 / 171209
• MGIID: 2159339
• Length: 563
• Species: Mus musculus
• Alignment Length: 604
• Identity: 111/604 - (18%)
• Similarity: 196/604 - (32%)
• Gaps: 197/604 - (32%)

  Fly    20 RRRKAGSVACEGFITTYHEYCRNTSIHGVQYLGEQERPFRERIFWLFVFLISIYGCSTLIQSAYT 84
            :||:|..:         ..:..:.::||:.::.........|..|....|:|:......:.....
Mouse    11 QRRQASDI---------RVFANSCTMHGLGHIFGPGGLTLRRGLWATAVLLSLAAFLYQVAERVR 66

  Fly    85 KWTETPVIVSFAEKST----PVWNIPFPAVTVCSETKRVLKQKGKETTYADLYSQFSEDMRASRV 145
            .:.|      |..|:|    ....:.|||||:|:                      ...:|.||:
Mouse    67 YYGE------FHHKTTLDERESHQLTFPAVTLCN----------------------INPLRRSRL 103

  Fly   146 FRPENVSALEMEEFRTLLHVCNTQIIEEDIPLIAGDDLDYFDVLQR--------MLPQFDRYFFY 202
             .|.:            ||...|.::..|    ..:...|...|.:        ..|.||....|
Mouse   104 -TPND------------LHWAGTALLGLD----PAEHAAYLRALGQPPAPPGFMPSPTFDMAQLY 151

  Fly   203 -------------CRWLSRFGEC-ETFFRKTLTEEGICYTFNGLRATEIYRDDTYQYQHSGEPLE 253
                         ||:  |...| ...|....|..|.|||||                 ||
Mouse   152 ARAGHSLEDMLLDCRY--RGQPCGPENFTVIFTRMGQCYTFN-----------------SG---- 193

  Fly   254 MENISSQHTAWTLETGYALDSDVETFPARVLSAGARSGIFLALQSFKQEVDYACRGPV------Q 312
                             |..:::.|.|    ..||.:|:.:.|.  .|:.:|.   |:      .
Mouse   194 -----------------AQGAELLTTP----KGGAGNGLEIMLD--VQQEEYL---PIWKDMEET 232

  Fly   313 GFKVGKFENVLLHAPDDVPQVSKQFVRIPMGKEVLIAVKPNMITM----------SSGIAEYHPV 367
            .|:||  ..|.:|..::.|.:.:.......|.:..::.:...::.          :|...::.|.
Mouse   233 PFEVG--IRVQIHGQEEPPAIDQLGFGAAPGHQTFVSCQQQQLSFLPPPWGDCNTASVDPDFDPE 295

  Fly   368 RRQCFLSHERSLRFFKVYTESNCQLECLANFTLTKCGCVKFSMPRNVDMPVCGEDK--------- 423
            ......|...|    ..|:...|:|.|.:.:...||||....||.|  .|||...:
Mouse   296 PSDPLGSPSSS----PPYSLIGCRLACESRYVARKCGCRMMHMPGN--SPVCSPQQYKDCASPAL 354

  Fly   424 -----------IHC---YDRAERELLVREFKRVKALNAGRENSRSVESACNCMPACTSLVYNTEI 474
                       ||.   ::...:.||....:...|:..        :..|.|...|.:..|..|:
Mouse   355 GKAHLFSLPVPIHSDIDHNPLGQVLLFLALRPADAMLR--------KDTCVCPNPCATTRYAKEL 411

  Fly   475 SQANFDLEEMLVAEGDTEFL-KEYPGSQ------MSRLSIYFKQSQFITSKRSELYGMTEFLANC 532
            |...      :.:.....:| ::|..|:      :..|.|:|:...:...::...|.::|.|.:.
Mouse   412 SMVR------IPSRASARYLARKYNRSETYITENVLVLDIFFEALNYEAVEQKAAYEVSELLGDI 470

  Fly   533 GGIFGLFMGFSILSLVEMI 551
            ||..|||:|.|:|:::|::
Mouse   471 GGQMGLFIGASLLTILEIL 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rpk	NP_001246909.1	ASC	39..552	CDD:279230	108/585 (18%)
Asic3	XP_006535700.1	ASC	21..546	CDD:383197	108/585 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8693
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.820