Protein Alignment rpk and Asic1

DIOPT Version :9

• Sequence 1: NP_001246909.1
• Gene: rpk / 40580
• FlyBaseID: FBgn0022981
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001276720.1
• Gene: Asic1 / 11419
• MGIID: 1194915
• Length: 559
• Species: Mus musculus
• Alignment Length: 592
• Identity: 112/592 - (18%)
• Similarity: 205/592 - (34%)
• Gaps: 190/592 - (32%)

  Fly     4 SDSELDSSKGIDLTFRRRRKAGSVACEG----FITTYHEYCRNTSIHGVQYLGEQERPFRERIFW 64
            |:||.:..|        .:::|....||    .:..:...|   ::||..::..:..|...:..|
Mouse    38 SESEEEEEK--------EKESGMELDEGDSPRDLVAFANSC---TLHGASHVFVEGGPGPRQALW 91

  Fly    65 LFVFLISI--YGCSTLIQSAYTKWTETPVIVSFAEKSTPVWNIPFPAVTVCSETKRVLKQKGKET 127
            ...|:|::  :.|....:.||  :...|.:....|.:|.  .:.|||||.|:
Mouse    92 AVAFVIALGAFLCQVGDRVAY--YLSYPHVTLLDEVATT--ELVFPAVTFCN------------- 139

  Fly   128 TYADLYSQFSEDMRASRVFRPENVSALEMEEFRTLLHVCNTQIIEED----IPL-------IAGD 181
                     :..:|.|::..|:            ||::.....::|.    :||       .:|:
Mouse   140 ---------TNAVRLSQLSYPD------------LLYLAPMLGLDESDDPGVPLAPPGPEAFSGE 183

  Fly   182 DLDYFDVLQRMLPQFDRYFFYCRWLSRFGECETF-FRKTLTEEGICYTFNGLRATEIYRDDTYQY 245
            ..:......|...:.:....||.:..  |.|... |....|..|.|||||.
Mouse   184 PFNLHRFYNRSCHRLEDMLLYCSYCG--GPCGPHNFSVVFTRYGKCYTFNS-------------- 232

  Fly   246 QHSGEPLEMENISSQHTAWTLETGYALDSDVETFPARVLSAGARSGIFLALQSFKQEVDYACRGP 310
            ...|.|             .|:|               :..|..:|:.:.|..  |:.:|.   |
Mouse   233 GQDGRP-------------RLKT---------------MKGGTGNGLEIMLDI--QQDEYL---P 264

  Fly   311 VQG------FKVGKFENVLLHAPDDVPQVSKQFVRIPMGKEVLIAVKP-------------NMIT 356
            |.|      |:.|  ..|.:|:.|:.|.:.:....:..|.:..::.:.             |.:|
Mouse   265 VWGETDETSFEAG--IKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQEQRLIYLPSPWGTCNAVT 327

  Fly   357 MSSGIAEYHPVRRQCFLSHERSLRFFKVYTESNCQLECLANFTLTKCGCVKFSMPRNVDMPVCGE 421
            |.|.                    ||..|:.:.|:::|...:.:..|.|....||.  |.|.|..
Mouse   328 MDSD--------------------FFDSYSITACRIDCETRYLVENCNCRMVHMPG--DAPYCTP 370

  Fly   422 DKI-HCYDRAERELLVREFKRVKALNAGRENSRSVESACNCMPACTSLVYNTEISQANFDLEEML 485
            ::. .|.|.|...|:.::                 :..|.|...|....|..|:|...      :
Mouse   371 EQYKECADPALDFLVEKD-----------------QEYCVCEMPCNLTRYGKELSMVK------I 412

  Fly   486 VAEGDTEFL-------KEYPGSQMSRLSIYFKQSQFITSKRSELYGMTEFLANCGGIFGLFMGFS 543
            .::...::|       ::|.|..:..|.|:|:...:.|.::.:.|.:...|.:.||..|||:|.|
Mouse   413 PSKASAKYLAKKFNKSEQYIGENILVLDIFFEVLNYETIEQKKAYEIAGLLGDIGGQMGLFIGAS 477

  Fly   544 ILSLVEM 550
            ||:::|:
Mouse   478 ILTVLEL 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rpk	NP_001246909.1	ASC	39..552	CDD:279230	105/553 (19%)
Asic1	NP_001276720.1	ASC	63..541	CDD:295594	105/559 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	91	1.000	Inparanoid score	I5086
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8693
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.870