Protein Alignment rpk and scnn1g

DIOPT Version :10

• Sequence 1: NP_001246909.1
• Gene: rpk / 40580
• FlyBaseID: FBgn0022981
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_031749443.1
• Gene: scnn1g / 100487822
• XenbaseID: XB-GENE-980897
• Length: 672
• Species: Xenopus tropicalis
• Alignment Length: 677
• Identity: 128/677 - (18%)
• Similarity: 224/677 - (33%)
• Gaps: 236/677 - (34%)

  Fly     5 DSELDSSKGIDLTFRRRRK---AGSVACEGFITTYHE----YCRNTSIHGVQYLGEQERPFRERI 62
            |..:.|..|..||.:.::.   .|..|     .|.:|    ||.||:.||.:.:...:...| |.
 Frog     7 DRSVMSKSGKKLTQKLKKNLPVTGPQA-----PTLYELMQWYCLNTNTHGCRRIVVSKGRLR-RW 65

  Fly    63 FWLFVFLISI----YGCSTLIQSAYTKWTETPVIVSFAEKSTPVWNIPFPAVTVCS--------- 114
            .|:.:.|.::    :.|:.|:.|.|:  ....:.|:|.:       :.|||||:|:
 Frog    66 IWIVLTLCAVALIFWQCALLLMSYYS--VSASITVTFQK-------LVFPAVTICNLNPYSYSKI 121

  Fly   115 ---------ETKRVLKQ-------------------------------------KGKETTYADLY 133
                     ||.:.||.                                     :|.:...:||.
 Frog   122 KDRLSALERETSQTLKNIYGFTEPLVRSKRDVEVDENSTDIFIKQIPLYRLESVQGNQLVVSDLK 186

  Fly   134 SQFSEDMRASRVFR------------------PEN------------VSALEMEEFRTLLHVCN- 167
            ::....|.|..:.|                  |.|            |:|:: |.:|  ||..|
 Frog   187 TKKRTRMSAKVIHRDAESVQDPGNMVGFKLCDPNNSSDCTIFTFSSGVNAIQ-EWYR--LHYTNV 248

  Fly   168 -TQIIEEDIPLIAGDDLD------YFDVLQRMLPQFDRYFFYCRWLSRFGECE----TFFRKTLT 221
             .:|..|| .:..|...|      :||.|                     .|:    |.|...|
 Frog   249 LAKISMED-KIAMGYKADELIVTCFFDGL---------------------SCDARNFTLFHHPL- 290

  Fly   222 EEGICYTFNGLRATEIYRDDTYQYQHSGEPLEMENISSQHTAWTLETGYALDSDVETFPARVLSA 286
             .|.|||||                                  :.|.|..|.|.:         .
 Frog   291 -YGNCYTFN----------------------------------SAERGNLLVSSM---------G 311

  Fly   287 GARSGIFLALQSFKQEVDYACRGPVQGFKVGKFENVLLHAPDDVPQVSKQFVRIPMGKEVLIAVK 351
            ||..|:.:.|  :..|.:|   .|......|  ..:|:|..|:.|.:......:....|..|.::
 Frog   312 GAEYGLKVVL--YIDEDEY---NPYLSTAAG--AKILVHDQDEYPFIEDLGTELETATETSIGMQ 369

  Fly   352 PNMITMSSGIAEYHPVRRQCFL-SHERSLR--FFKVYTESNCQLECLANFTLTKCGCVKFSMPRN 413
               :|.|:.:::.:   ..|.: ..:.|:.  :.|.||...|...|.....:..|||..:..|..
 Frog   370 ---LTESTKLSDPY---SDCTMDGSDVSVENLYSKKYTLQICLNSCFQREMVRTCGCAHYDQPLP 428

  Fly   414 VDMPVCGEDK----IHCYDRAERELLVREFKRVKALNAGRENSRSVESACNCMPACTSLVYNTEI 474
            .....|..::    |:||.:..::.:..|.              ..:|||.  .:|:...:....
 Frog   429 NGAKYCNYEEYPSWIYCYFKLYKQFVQEEL--------------GCQSACR--ESCSFKEWTLTR 477

  Fly   475 SQANFD-------LEEMLVAEGDTEFLKEYPGSQMSRLSIYFKQSQFITSKRSELYGMTEFLANC 532
            |.|.:.       :..:|..|...:..|....:.::.|:|:::.....:...|..|.:...|:|.
 Frog   478 SLAKWPSLNSEQWMLRVLSWELGEKLNKNLTKNDLANLNIFYQDLNSRSISESPTYNIVTLLSNF 542

  Fly   533 GGIFGLFMGFSILSLVEMIYHFTLRLF 559
            ||..||:|..|::.::|::..|.:..|
 Frog   543 GGQLGLWMSCSMICVLEIVEVFFIDSF 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rpk	NP_001246909.1	ASC	39..552	CDD:459966	117/627 (19%)
scnn1g	XP_031749443.1	ENaC	35..651	CDD:273304	121/644 (19%)