Protein Alignment LTK and Ltk

DIOPT Version :9

• Sequence 1: XP_016877670.1
• Gene: LTK / 4058
• HGNCID: 6721
• Length: 885
• Species: Homo sapiens
• Sequence 2: NP_001101233.2
• Gene: Ltk / 311337
• RGDID: 1309323
• Length: 577
• Species: Rattus norvegicus
• Alignment Length: 576
• Identity: 443/576 - (76%)
• Similarity: 469/576 - (81%)
• Gaps: 31/576 - (5%)

Human   310 AAAGGFGGGGGACTAGGGGGGYRGGDASETDNLWADGEDGVSFIHPSSELFLQPLAVLLLTVTEN 374
            |||.|.|..|||.          |||.||:|.||||||||:||:|||.||:|||||     |||.
  Rat     5 AAAQGSGRRGGAA----------GGDTSESDLLWADGEDGISFVHPSGELYLQPLA-----VTEG 54

Human   375 HGEVEIRRHLNCSHCPLRDCQWQAELQLAECLCPEGMELAVDNVTCMDLHKPPGPLVLMVAVVAT 439
            ..|||||||.|||||..:||||||||..|||:|||||||||||:||..|.....||::|.|||..
  Rat    55 DVEVEIRRHPNCSHCSFKDCQWQAELWRAECICPEGMELAVDNITCTGLPTTTSPLIMMGAVVTA 119

Human   440 STLSLLMVCGVLILGTKRLAGTVDSRLLLSMKQKKWQGLQEMRLPSPELELSKLRTSAIRTAPNP 504
            .||||||:||||||                :.|||.|.|:..|||.|||||||||||||||||||
  Rat   120 LTLSLLMMCGVLIL----------------VNQKKCQSLRGTRLPGPELELSKLRTSAIRTAPNP 168

Human   505 YYCQVGLGPAQSWPLPPGVTEVSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPE 569
            |||||||.|||:||||.|:|||||||||||||||||||||||||||||||||||||.||||||||
  Rat   169 YYCQVGLSPAQAWPLPQGLTEVSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLPVAIKTLPE 233

Human   570 LCSPQDELDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHLGQPS 634
            ||||||||||||||||||||.|||||||||||.:|.||||||||||||||||||||||||.||.|
  Rat   234 LCSPQDELDFLMEALIISKFSHQNIVRCVGLSFQAAPRLILLELMSGGDMKSFLRHSRPHPGQLS 298

Human   635 PLVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRASYYR 699
            ||.|:|||||||||||||||||||||||||||||||||||:|.||||||||||||||||:|||||
  Rat   299 PLTMQDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCSGDSRVAKIGDFGMARDIYQASYYR 363

Human   700 RGDRALLPVKWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGGRMD 764
            :|.|.|||||||||||.|||:|||||||||||||||||||||||||||.||||||||:..|.|||
  Rat   364 KGGRTLLPVKWMPPEALLEGLFTSKTDSWSFGVLLWEIFSLGYMPYPGHTNQEVLDFIATGNRMD 428

Human   765 PPRGCPGPVYRIMTQCWQHEPELRPSFASILERLQYCTQDPDVLNSLLPMELGPTPEEEGTSGLG 829
            |||.||||||||||||||.:|||||.|||||||:|||.||||||||.||||.||..||||.||.|
  Rat   429 PPRNCPGPVYRIMTQCWQLQPELRPDFASILERIQYCIQDPDVLNSPLPMEPGPIVEEEGASGPG 493

Human   830 NRSLECLRPPQPQELSPEKLKSWGGSPLGPWLSSGLKPLKSRGLQPQNLWNPTYRS 885
            |||||.||.|:..|||.:.|||.||..||..|.||||.|.||.|||||:|||||.|
  Rat   494 NRSLEGLRSPKTLELSSQNLKSRGGDLLGSQLPSGLKTLTSRCLQPQNIWNPTYGS 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LTK	XP_016877670.1	None
Ltk	NP_001101233.2	PTKc_ALK_LTK	188..464	CDD:270632	248/275 (90%)
		Pkinase_Tyr	195..462	CDD:285015	240/266 (90%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83685835
Domainoid	1	1.000	499	1.000	Domainoid score	I7283
eggNOG	1	0.900	-	-		E2759_KOG1095
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H130502
Inparanoid	0	0.000	Not matched by this tool.
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG46753
OrthoDB	1	1.010	-	-		D17765at314146
OrthoFinder	1	1.000	-	-		FOG0002954
OrthoInspector	1	1.000	-	-		oto137777
orthoMCL	1	0.900	-	-		OOG6_105014
Panther	1	1.100	-	-	LDO	PTHR24416
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X12401
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	16.260