Protein Alignment slx1 and Slx1b

DIOPT Version :10

• Sequence 1: NP_649484.3
• Gene: slx1 / 40578
• FlyBaseID: FBgn0037263
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_083696.2
• Gene: Slx1b / 75764
• MGIID: 1915220
• Length: 270
• Species: Mus musculus
• Alignment Length: 287
• Identity: 113/287 - (39%)
• Similarity: 152/287 - (52%)
• Gaps: 42/287 - (14%)

  Fly    15 ESVALKGHFYGVYLLCSQSLDPRYRGKCYVGFTVNPKRRIRQHNLGCDFGGARKTSRKGPWLMVM 79
            :..|..|.|:|||||..|  :||:||:.||||||||.||:||||.|...|||.:||.:|||.||:
Mouse     2 DHAARPGRFFGVYLLYCQ--NPRHRGRVYVGFTVNPARRVRQHNAGRKKGGAWRTSGRGPWDMVL 64

  Fly    80 IVHGFPNNTVALQFEWAWQQPSLSTRLKMYPELKRKLPRETFFDYNFRILSNMLGVGPWNRLPLT 144
            |:||||:...||:||||||.|..|.||   ..:..:|..|..|.::.|:|::||.|.||.|||||
Mouse    65 IIHGFPSAVAALRFEWAWQHPQASRRL---THVGPRLRSEAAFAFHLRVLAHMLRVPPWVRLPLT 126

  Fly   145 VRWLETDYERPFSKALPKHMEIVSGKVSISASQRRRPDDAVPPPP-------------------- 189
            :|||..|:......|.|.||.|..|                ||||
Mouse   127 LRWLRPDFRHELCPAPPAHMPIAFG----------------PPPPQPLVPKRPAVSEADSERQLD 175

  Fly   190 VAWASECHLCMQEMEQPEKSRLGCTNQMCRLTCHMVCLANYLLGDEPGHYIPVGGECPLCETRLS 254
            :...:.|.||.: :.|.|:..|.|.:..|.|..|::|||...|.:|||..:|:.|.||.|:..|.
Mouse   176 LGTKARCSLCAR-LLQDEEGPLCCPHPGCPLRAHIICLAEEFLQEEPGQLLPLEGHCPSCKKSLL 239

  Fly   255 WAALLQRKRLLLGVPEELQDHDEDLSD 281
            |..|:.:........|:|:..:|..:|
Mouse   240 WGNLVGQCHADTEEEEDLELEEEHWTD 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slx1	NP_649484.3	GIY-YIG_SLX1	23..101	CDD:198402	49/77 (64%)
Slx1b	NP_083696.2	GIY-YIG_SLX1	10..85	CDD:198402	49/76 (64%)