Protein Alignment 5-HT2A and LOC1274064

DIOPT Version :10

• Sequence 1: NP_730859.1
• Gene: 5-HT2A / 40575
• FlyBaseID: FBgn0087012
• Length: 930
• Species: Drosophila melanogaster
• Sequence 2: XP_061497507.1
• Gene: LOC1274064 / 1274064
• VectorBaseID: AGAMI1_002176
• Length: 772
• Species: Anopheles gambiae
• Alignment Length: 320
• Identity: 59/320 - (18%)
• Similarity: 97/320 - (30%)
• Gaps: 103/320 - (32%)

  Fly     4 QSYSGRGPSTGTSETATATAAVASA----------SASDTAATFTLRHFNCRLEEADWPGPRQPF 58
            |:...:.|||....:|::..:|.:|          ........|.|:.....||:.:.....:..
Mosquito   113 QTAKSKAPSTRRGGSASSQLSVRNALERLAKKQELEKKMAEKEFQLKMAKMELEQEELRMQLEEQ 177

  Fly    59 IDCEGSH-----------------TNSTSYTPSSLPTSKNLIEGPNNTFQCARQAIDEA--EHN- 103
            :|.|||.                 .|.....|:.:.|.......|....:.|...::.|  |.|
Mosquito   178 LDIEGSECSIISGKSVRAKIWVRDQNQALAKPAQVQTHPQTEASPVTKRRIAENNLENAMVERNG 242

  Fly   104 ---------------------------AFYSCDGESPLSENCTLRLKARLLRWPYEAYEHIRLAI 141
                                       .|.||..||  :|.|....:..|||        :...:
Mosquito   243 LTPSQITARNHYPKQLPKFSGSPKEWAVFISCYNES--NEACGFSNRENLLR--------LEECL 297

  Fly   142 NGALSDYASDKLSDSSSCDEGGMVLQCKLGQAH---ELLLCHLQQLER------EPLREVGSA-- 195
            :||..:....||:..::..:...||:...|:..   :.|:...:|.|.      |.|.:.|.|
Mosquito   298 HGAAREAVQSKLTTPNAVPDIIKVLKRLYGRPALIVQELIDKARQTEAPKPENLESLIKYGLAVQ 362

  Fly   196 -----------EESFSNDSLLQAFQIELGAERDGLWSFLN--------------LSELME 230
                       |:...|.::|.....:|.|.|...||...              :.||||
Mosquito   363 HFCDHLVAADLEDHLQNPAILGELVEKLPASRRLEWSRYKCGLPHISLQQFGEFMDELME 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT2A	NP_730859.1	7tm_GPCRs	298..>473	CDD:475119
		TM helix 2	321..343	CDD:410628
		TM helix 3	359..381	CDD:410628
		TM helix 4	404..420	CDD:410628
		TM helix 5	443..466	CDD:410628
		7tm_GPCRs	<779..858	CDD:475119
		TM helix 6	792..814	CDD:410628
		TM helix 7	826..851	CDD:410628
LOC1274064	XP_061497507.1	None