Protein Alignment Fip1 and fip1l1

DIOPT Version :10

• Sequence 1: NP_649476.1
• Gene: Fip1 / 40569
• FlyBaseID: FBgn0037255
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: XP_031756888.1
• Gene: fip1l1 / 733481
• XenbaseID: XB-GENE-985496
• Length: 606
• Species: Xenopus tropicalis
• Alignment Length: 745
• Identity: 200/745 - (26%)
• Similarity: 296/745 - (39%)
• Gaps: 221/745 - (29%)

  Fly    19 STTGEL--------GNGGDSLTAEHESAAAEAQALAELVAGEKPGASAGTNSTEDSPRCPKEEVP 75
            |..|||        |.||.:........::...|......|...|...|....|       ||..
 Frog     2 SAGGELVERMVVSSGTGGSTAPTISSPVSSAVTAPVSASTGAAGGGGGGGGGDE-------EEEW 59

  Fly    76 EYSEFDDPAQEMEEDEDALPNTDSRSRRERDRERDRGRCADRADARSSPDPEDDEMSDGPAARRE 140
            .|.         ||:|.|.|:.|..               |...:...|..|.:...:|......
 Frog    60 LYG---------EENEAAAPDDDEE---------------DITSSHPVPGIEAEATENGVVKTVT 100

  Fly   141 RNGSGSDDDEDDDSDDDINVVIGDIKQ-APSTYNIKQRP---NLLAGGT--GAAGDKAKPAGQAG 199
            .....|:.|.||| |||::|.|||||. ||........|   |:..||.  |..|.|.|..
 Frog   101 ETEDDSESDSDDD-DDDVHVTIGDIKTGAPQYVPYGTTPVNLNIKTGGRIYGPTGGKGKGV---- 160

  Fly   200 KFSIEDFEGAGTINGVAVHEFSIDSLEEKPWRKPGADITDYFNYGFNEETWRAYCERQKRFRVAE 264
                 |.:..|:||||.:.|..:||.|:|||||||||::|||||||||:||:||||:|||.|:..
 Frog   161 -----DLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRLRMGL 220

  Fly   265 SGVGLASLTQNVNQNAPIGILTDGGMGMGPPGMHSIQSMVGMGGESGMQMPPPGMPPPMMQHQSR 329
            ..:.::|.|..:.       :..|..|...  ..::...|.....|...:..||:|||  ..::.
 Frog   221 DALPVSSTTNKIT-------VQQGRTGNAE--KDTVLQSVKPEFTSPTSLFKPGVPPP--SRKTS 274

  Fly   330 SGMGLMQRPPRPISTTGGDRGGDRERAVKENAIQVMTAEC-REYSRGGLGPMAPNFPLPGASEEP 393
            |.:.::.:      ||...|...|.|...|:.|||::.:. .|.....:.|..|.|| |||   |
 Frog   275 SAIDVIGQ------TTTITRVEGRRRGANESNIQVVSEQSPSEVDNNFIKPPPPFFP-PGA---P 329

  Fly   394 FFHEPEPFDYGYEPTQESQWNNDNAGWVPSGIKELTPGHAHMQQPPPGMPPPG------------ 446
            ..|.|.|                          .|.|...::...||.:||||
 Frog   330 PTHLPPP--------------------------PLFPPPPNVSTAPPLIPPPGSISFSMQKPSRY 368

  Fly   447 ---MSVPPPQMGGPPPNLRGIMPPNMRMPPNMNMGPPPGMMMGGNAPPQMRMGMAPPQRLAMGDR 508
               ::||||:..|...::|.:.|.:...||  ..||||.::      |.:..|
 Frog   369 GIPITVPPPEKTGKKVSVRKMSPEHSFPPP--PGGPPPSLI------PTIESG------------ 413

  Fly   509 GAYDDDRERRRREKEKLLKKDQLRKDFLDMLRERHDIERHTRWYDIKK---------KF-----E 559
                                                   |:..||.:.         .|     .
 Frog   414 ---------------------------------------HSSGYDGRSAPAFPYGSVSFPHMPGS 439

  Fly   560 ADPRYRALDSSYREEYFEDYLHLLKEEKRKERDLKERERHRDKERSRDKDKDKDKEKDKDKDKDK 624
            |.|....:|::...:|:          .|:|:| ::|||.||::|.||:|:|:::.:::::|:::
 Frog   440 AGPWSSLVDTAKPWDYY----------PRREKD-RDRERERDRDRDRDRDRDRERVRERERDRER 493

  Fly   625 EKD---------KEKDKDKDKE-KEKDKESSRRERSR-SREKSSR-RKSKSREKDRSER--SSKS 675
            |:|         .|:::.:.|| .|:.:.|..|.|.| ||||..| |:.:.|||:.|.|  ||:|
 Frog   494 ERDHSPSAGAYNSEEERYRYKEYSERTERSYERHRERISREKEERHRERRHREKEESSRHKSSRS 558

  Fly   676 SS-----SNTGGSSSRSEKKKSHRKDKEED 700
            ||     |..|.|..|.:.|||.|..:.:|
 Frog   559 SSRRRHDSEEGDSHRRHKHKKSKRSKEGKD 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fip1	NP_649476.1	Fip1	219..261	CDD:461573	31/41 (76%)
		FF	530..579	CDD:426471	8/62 (13%)
fip1l1	XP_031756888.1	Fip1	175..217	CDD:461573	31/41 (76%)