Protein Alignment Fip1 and fip1l1b

DIOPT Version :10

• Sequence 1: NP_649476.1
• Gene: Fip1 / 40569
• FlyBaseID: FBgn0037255
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_001006042.1
• Gene: fip1l1b / 450021
• ZFINID: ZDB-GENE-041010-138
• Length: 570
• Species: Danio rerio
• Alignment Length: 748
• Identity: 191/748 - (25%)
• Similarity: 269/748 - (35%)
• Gaps: 256/748 - (34%)

  Fly     7 EDSWLYGTSNPDSTTGELGNGGDSLTAEHESAAAEAQALAELVAGEKPGASAGTNSTEDSPRCPK 71
            |:.|||            |:.|:|...|.|.|.                .:|..::|..:|
Zfish    20 EEEWLY------------GDEGESKETEEEEAK----------------LTAAISATSTTP---- 52

  Fly    72 EEVPEYSEFDDPAQEMEEDEDALPNTDSRSRRERDRERDRGRCADRADARSSPDPEDDEMSDGPA 136
                           :.||.....|..|.|                    ::|........:|.|
Zfish    53 ---------------VAEDAPTTTNNSSDS--------------------ATPPTTTTTTGNGVA 82

  Fly   137 ARRERNGSGSDDDED-DDSDDDINVVIGDIKQ----------APSTYNIKQRPNLLAGGTGAAGD 190
            ::.|..|...|.:.| ||.|||:.|.|||||.          .|...|||           :||.
Zfish    83 SQEEAPGEDEDSESDSDDDDDDVRVTIGDIKTGAPQYTGYGGTPVNLNIK-----------SAGS 136

  Fly   191 KAKPAGQAGKFSIEDFEGAGTINGVAVHEFSIDSLEEKPWRKPGADITDYFNYGFNEETWRAYCE 255
            :|..||  .|....|.|..|:||||.|.|..::|.|||||||||||::|||||||||:||:||||
Zfish   137 RAYGAG--AKVKGVDLEAPGSINGVPVLEADMESFEEKPWRKPGADLSDYFNYGFNEDTWKAYCE 199

  Fly   256 RQKRFRVAESGVGLASLTQNV--------NQNAPIGILTDGGMG--MGPPGMHSIQSMVGMGGES 310
            :|||.|:....:.:.|.|..:        |....|.|.......  ..|..::.      .|...
Zfish   200 KQKRLRMGLDVLNIGSTTSKISVQQGRTGNNEKEITIPAHASKAEFTSPSNLYK------AGLNQ 258

  Fly   311 GMQMPPPGMPPPMMQHQSRSGMGLMQRPPRPISTTGGDRG------GDRERAVKENAIQVMTAEC 369
            |...||....||...      :....:.|..|...||...      |.|...::.|.|||::
Zfish   259 GRISPPHWAGPPSQD------LSYYTKTPGTIDVIGGQTATISRVEGRRRHNLEGNNIQVIS--- 314

  Fly   370 REYSRGGL--------------GPMAPNFPLPGASEEPFFHEPEPFDYGYEPTQESQWNNDNAGW 420
             |:|...:              ||:.||.|.|     ||...|
Zfish   315 -EHSSSEVEPEVQKMPPPFFPPGPLPPNIPPP-----PFLPPP---------------------- 351

  Fly   421 VPSGIKELTPGHAHMQQPPPGMPPPGM--SVPPPQM----GGPPPNLRGIMPPNMRMPPNMNMGP 479
                          :.|.||.:||..|  :||||..    |||||:|         :|...|.|.
Zfish   352 --------------VSQAPPLIPPHRMPITVPPPNFPPPTGGPPPSL---------IPTLDNSGH 393

  Fly   480 PPGMMMGGNAP-PQMRMGMAPPQRLAMGD-RGAYDDDRE-----RRRREKEKLLKKDQLRKDFLD 537
            |.|......|| |....|..||.:.|:.. .|..::.::     ||.:|:||            :
Zfish   394 PGGYDGRPVAPYPFPTGGFPPPMQGAVNPWPGLMENPKQWDYYPRRDKEREK------------E 446

  Fly   538 MLRERHDIERHTRWYDIKKKFEADPRYRALDSSYREEYFEDYLHLLKEEKRKERDLKER--ERHR 600
            ..|||.....|.|.:..    .|.| |.::.....||.:..|           ||..:|  ||||
Zfish   447 RERERQRDRGHERDHSP----NAGP-YNSMAMCSDEERYRSY-----------RDYGDRGYERHR 495

  Fly   601 DKERSRDKDKDKDKEKDKDKDKDKEKDKEKDKDKDKEKEKDKESSRRERSRSREKSSRRKSKSRE 665
            ::                       ..:||::.....:.::||..|.:.|||   ||||:.:|.|
Zfish   496 ER-----------------------ASREKEERHGGRRHREKEEGRHKSSRS---SSRRRHESEE 534

  Fly   666 KDRSERSSKSSSSNTGGSSSRSEKKKSHRKDKE 698
            .|...|.....|..:......||::.:.::::|
Zfish   535 GDSHRRHKHKKSKRSKEGKEPSEERSADQENQE 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fip1	NP_649476.1	Fip1	219..261	CDD:461573	31/41 (76%)
		FF	530..579	CDD:426471	10/48 (21%)
fip1l1b	NP_001006042.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..107		30/153 (20%)
		Fip1	163..205	CDD:461573	31/41 (76%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..328		7/31 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	371..400		12/37 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	418..570		45/204 (22%)