Protein Alignment sac and Dhc1

DIOPT Version :10

• Sequence 1: NP_649475.3
• Gene: sac / 40568
• FlyBaseID: FBgn0037254
• Length: 1079
• Species: Drosophila melanogaster
• Sequence 2: NP_001287256.1
• Gene: Dhc1 / 41171
• FlyBaseID: FBgn0287844
• Length: 4724
• Species: Drosophila melanogaster
• Alignment Length: 1333
• Identity: 244/1333 - (18%)
• Similarity: 433/1333 - (32%)
• Gaps: 458/1333 - (34%)

  Fly     4 ENLEVGQNYEGSQEFDESSTSSISNKGPD-----DSQFKREAEKAICIMPPRPGTTMMNYQELYI 63
            |.|.:|:..|.:....|.:...::::..|     :|.|..:.|:.|     ....::.:.....|
  Fly   536 EGLLLGEALEDASNHFEEAKKEVTSRKYDYLDHRNSDFNIDFERFI-----HKTNSLKDTIATLI 595

  Fly    64 PRNQLTDVYYPIQEAQRWLTLMDKMGKAHRFPLPTILPKVIQ-TRYVPKRHLPKDVEVDRRRRQY 127
            .::  .|..:...:..|:|...:|:  :.:.||..:..|..: .|||.|       ||||..:.:
  Fly   596 EKD--FDTVWETPQCIRFLVRFEKV--SEKIPLTRMDEKYTRILRYVEK-------EVDRILKTF 649

  Fly   128 QKINLVNELAK-----AG--------------LTDDVLQPTEEQYNVMSEFAFPHKFPLSY---- 169
            :|......||:     ||              |.|.|:     ::.|:|.........:.|
  Fly   650 RKQRDDPPLARNFPPIAGRIHWCRALSLHITELMDAVM-----EHVVLSSLPMAKDLDVRYHNVL 709

  Fly   170 -----FDDSNFDINSPAAWFELGV-VGDAHYPLPAKAYLPYNQSLLNCQWGMAAVTAHH------ 222
                 ::|....|     |.:..| |.||....|          ||:.|.....|..|.
  Fly   710 GILQEYEDEIVSI-----WLDQDVSVADACLLQP----------LLSLQGDKLFVNLHPTIPLLI 759

  Fly   223 EDSDLWTLLSLE---DGCTYTVPKLQFMFMAEDPHKYIKRLQAAVHE-RHKGEQLMLMELI-VDC 282
            .::.:...|.:|   ...|....:..|:.:.:..:..||...:.|.. :.:...|.|.:|: :..
  Fly   760 REAKMLAKLDIELPIVAATLMSRQQYFITIQDSLNCLIKMFLSTVRAVKLEVRPLFLPQLVRLTA 824

  Fly   283 VLHEDIES--------TVFYSFKPIESVLQAAKVSEQCKRRLRS-EV----------NLVFERLM 328
            :|...:.:        |.||               |:||:.:.| :|          |.:...||
  Fly   825 MLKPGLHTINWTNQNWTEFY---------------ERCKQAIESFDVLVARVHDIYSNRILHVLM 874

  Fly   329 ALYELEQFILKMPKEFPQFRNINLKEFLPRSFAVDVSGKERLELQALGITMQEKRYDYLKASLFY 393
            .:.::...||....|.     ..:.|||.||       :|.....|:.:..:.:
  Fly   875 WMQDVSLQILPADDEI-----WTVDEFLERS-------EEACRKAAIELNRKSQ----------- 916

  Fly   394 CVGGIEAMAGVAIECQYIETLSIFICSFSKPLALVDFLQA--QEAHSDNVATFLKVYWP------ 450
                   |...|:|               :.|:|||...|  :|...|:|.|......|
  Fly   917 -------MVSEAVE---------------EVLSLVDRATAAFKEIAGDDVITLFDAATPKGDNSG 959

  Fly   451 -----------------------------QQ------------LTTVITVVLRALGKGWLDISLN 474
                                         ||            |:.:.|.  .:|.||..|:..|
  Fly   960 SGGRKPEDGGGGGGGAAAPSTSGGGGGGQQQDWSILWSCFENPLSLLSTT--ESLPKGMQDMVCN 1022

  Fly   475 TWTVYLMCKISRFILQVKFRMQESMEVLLETSLMNFSHFVCDPCLQFLELKSNYKWTNNYIDTEF 539
            . .|.:....||.::.|..::   :...|:|..   ..|:.|                   :.|.
  Fly  1023 A-VVEMRRYYSRKVIDVLIKV---IRAALDTLR---RRFIAD-------------------ENET 1061

  Fly   540 PFQKPVFAMTLGISEDRKVFYSTDPDEFQPGLVEIFKKCLEKSSGVRCIDGSVMSFLKFAPNLYI 604
            .|:|||||:...: :...|....:.||.|..||...|.....:.||     :..|..|..|.: .
  Fly  1062 VFKKPVFALHAQL-QIPHVVIKPNLDELQDILVTAGKNITGIAKGV-----AQWSSGKDPPQV-S 1119

  Fly   605 LTVE-----------------------LIEDRFLRENELLKNCY---------AKAVLPLRAYAR 637
            :||:                       |..:...:...:||:.|         ||||..|.:..:
  Fly  1120 MTVQPRVGRNHNESTGGGKSRRRKIYCLASEERPQMPHMLKSFYSAIMDNKEVAKAVNQLASCTK 1184

  Fly   638 LYERFIDFYLLNVNTYMQAYAQAHKPSSEVKRDILENKRLKEELREI-LPAFITIGPFYINVDTM 701
                       ||...:|.|.:..||    ...:.:|.|...:|.|. |..|.|......::|.
  Fly  1185 -----------NVKPEIQTYIKRWKP----YHFLWKNDRTTRQLMEFGLQEFETTLRCLSDLDA- 1233

  Fly   702 KQFMIKKRIEVVRRIFEYYVDRMYETNEVLLDRC-----------------------LEMFRRIA 743
             ..:::..:||..:....|.:::.....:.:..|                       .||.|::
  Fly  1234 -NLLVEPDMEVFGQCVAVYNEKLKYGLAIEIKSCNHKIGQAMKKKYKKEMDYVYAVINEMDRKL- 1296

  Fly   744 ERPISIEHLYEIRDFAQTVPDL----VD-ELKAD-------------IQVMWLEYDLLDSFFYNL 790
            :||  |..|.::|...:|:..:    || ||:.|             :||...::||:|    ||
  Fly  1297 DRP--IRDLDDVRMIMETLGKIREQEVDMELRIDPIEEAFNVLTRYEVQVEREQFDLVD----NL 1355

  Fly   791 SDHQFAMKWNVYAWPHQIMVRL----STLKDEQKVDIEDFLR---------LHASECQA------ 836
            .    |...|:.|...|..|:|    ...:|:.:.::::|.:         ..|...||
  Fly  1356 R----ATFQNLLAGALQAQVKLLDMQPAFQDDLRTNLDNFKQDKISYVTEYRTAGPMQAGLTPRE 1416

  Fly   837 -------FEERLESLNDEVQAYSLAFNTNRAQETSVDIKKTWALIKELEKVSQTLQFRQELFELE 894
                   |:.|.|.:...:|.|..........:|.         ..||.::.:.|...|:|::|
  Fly  1417 ASDRLILFQNRFEGMWRRLQTYQSGEELFGLPQTD---------YPELGQIRKELNLLQKLYKL- 1471

  Fly   895 PLSVEFLESIIASFTPYKNLWYGCANFLKLEDATLGNPIAQLDLEDVWNNLMRLRDELNESMKIF 959
                  ...:|...:.|.::                 |..::|:|::.|.||..::...:..|..
  Fly  1472 ------YNDVIDRVSSYYDI-----------------PWNEVDIEEINNELMEFQNRCRKLPKGL 1513

  Fly   960 HEKVEIMDVAKTFIAKIDDFVPVYNSIKDIRNENWMYIHWQELSAITGQEIKYSVAMNYQYLIRK 1024
            .|......:.||    ||||..:...::.:.|:.....|||.:..:|    :|....:.:....|
  Fly  1514 KEWPAFHALKKT----IDDFNDMCPLLELMANKAMKPRHWQRIMDVT----RYIFEFDSEGFSLK 1570

  Fly  1025 GILDV--------LPEVHIISEKA------------------------NNEAEEIRRAIEEEERR 1057
            .||:.        :.::.|.:.|.                        ||..|.:.|.....|..
  Fly  1571 NILEAPLLKHKEDIEDICISAMKEKDIEAKLKQVTNEWSVHELQFMSFNNRGELLLRGDTTAETI 1635

  Fly  1058 KQAELNAMLL------------RKQLRKCRRDI 1078
            .|.|.:.|:|            |||:::...|:
  Fly  1636 GQLEDSLMVLGSLLSNRYNAPFRKQIQQWVYDL 1668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sac	NP_649475.3	DHC_N2	901..>1042	CDD:462462	27/172 (16%)
Dhc1	NP_001287256.1	DHC_N1	287..843	CDD:462457	62/342 (18%)
		DYN1	1178..4372	CDD:227570	103/560 (18%)
		DHC_N2	1455..1860	CDD:462462	45/246 (18%)
		AAA_6	1994..2321	CDD:463697
		Dynein_C	4425..4721	CDD:465677