DRSC/TRiP Functional Genomics Resources

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Protein Alignment sac and Dnah3

DIOPT Version :10

Sequence 1:NP_649475.3 Gene:sac / 40568 FlyBaseID:FBgn0037254 Length:1079 Species:Drosophila melanogaster
Sequence 2:NP_001357735.1 Gene:Dnah3 / 381917 MGIID:2683040 Length:4072 Species:Mus musculus


Alignment Length:634 Identity:125/634 - (19%)
Similarity:207/634 - (32%) Gaps:222/634 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   218 MVGEVCVNPYHYEIVIGTMIVGQRDHDNRDMPPPHQRYHTPGRQDPVDDMSRFIPPASI------ 276
            ::|:.|..|......:||  .|:        ||..::...|.....|.:.:|   |.|.      
Mouse    27 LLGKPCKLPVSSNCQMGT--TGK--------PPMLEQTPVPQTNPGVKERAR---PESTSQSTNY 78

  Fly   277 ----RPPPMNMHT-------RP-QPMPQ-------QLPSVGATFAHPLPH---QAPHNPGVSHPY 319
                ||.|..:.|       || :|:.|       .|.|:..| ..|||:   |.|.:|...   
Mouse    79 ISISRPRPTALGTKASIKVSRPTEPLLQVKATGMANLLSISPT-ESPLPYCNSQKPTSPTSQ--- 139

  Fly   320 SIAPQTHYPLNMNPIPQMPQMPQMPPPLHQGYGMNG-----PSCSSENN-----NPFHQNHHYND 374
                     |..|| |.:|  |.:|.|..|....|.     |...|.:|     ||.||.....|
Mouse   140 ---------LGFNP-PSIP--PTLPSPPAQPIRANTLNNLMPKPVSNSNPSPPPNPVHQLIQSQD 192

  Fly   375 ISH---------------------------------PNHYSYDCGPNLYG-----FPTPYPDFHH 401
            :.:                                 |:..:...||.:..     |.....:.:.
Mouse   193 VPNAGDTTDKKLNKAINEEGDFRVHIVTWNVGSGMPPDDITSLFGPGIENGSTDMFVVGLQEVNS 257

  Fly   402 PFNQQ------PHQPPQLSQNHTSQQGSHQPGHQGQVPNDPPISRPVLQPST----VTLDVFRRY 456
            ..|::      ..|..:|..:..|:.|.                  ||..|.    |.|.||.::
Mouse   258 MINKRLKDALFTDQWSELCMDTLSRFGY------------------VLVASQRMQGVFLLVFSKF 304

  Fly   457 CRQTFGNRFFEGESEQSGAIIRSSNK-----FIEEFDSPICGVTVVRP--------RMTDGE-VL 507
            |...| .|..:.:|.::|......||     .:..|..|:|.:....|        ||.|.| :|
Mouse   305 CHLPF-LRGVQTQSTRTGLGGYWGNKGGVSARMMVFGHPVCFLNCHLPAHMRNLEQRMEDFESIL 368

  Fly   508 ENIMPEDAPY-----HDICKFILRLTSESVTFSGEGPEVSDL-----NEKWGTIVYYEKNLQIGE 562
            :....|.:..     ||:..:.     ..:.|..||.::..:     |:|. .:::.:..|.:.:
Mouse   369 QQQQFEGSNAVGVLDHDVVFWF-----GDLNFRIEGYDIHVVKSAIENDKL-PLLWEKDQLNMAK 427

  Fly   563 KKCSRGNFHVDGGFICSENRYSLGLEPNPIREPVAFKV--------------RKAIVDGIRFSYK 613
            |..|     |..|||           ..|::.|..:|.              :.|..|.|.:..:
Mouse   428 KSES-----VLEGFI-----------EGPLKFPPTYKFDVGTHTYDTSAKKRKPAWTDRILWRLR 476

  Fly   614 KDGSVWLQNRMKYPVFVTSGYLDEQSGGLKKDKVHKVYGCASIKTFGFNVSKQIIRDALLSKQMA 678
            :.||....:.......:||..     ||..:...|  :.|:.:   ||.:|......||.|    
Mouse   477 RTGSPVPSHNSALQRGLTSWL-----GGATRVSQH--FYCSHM---GFTISDHKPVSALFS---- 527

  Fly   679 TMYLQGKLT-PMNYIYEKKTQEELRREATRTTDSLAKYCCVRVSFCKGF 726
             ::...|:| |:..:       |:.:|.|:.:|:     .|:::...||
Mouse   528 -LHFPFKVTLPLVTL-------EVEKEWTKFSDA-----TVKLTMAHGF 563

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sacNP_649475.3 DHC_N2 901..>1042 CDD:462462
Dnah3NP_001357735.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..37 3/9 (33%)
DHC_N2 815..1221 CDD:462462
DYN1 1018..3745 CDD:227570
AAA_6 1347..1673 CDD:463697
AAA 1. /evidence=ECO:0000250 1347..1568
AAA 2. /evidence=ECO:0000250 1628..1859
AAA 3. /evidence=ECO:0000250 1992..2240
AAA 4. /evidence=ECO:0000250 2351..2602
AAA_8 2360..2620 CDD:463701
Stalk. /evidence=ECO:0000250 2617..2916
AAA 5. /evidence=ECO:0000250 3001..3231
AAA 6. /evidence=ECO:0000250 3444..3668
Dynein_C 3767..4068 CDD:465677
Blue background indicates that the domain is not in the aligned region.

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