Protein Alignment sac and Dnah7

DIOPT Version :10

• Sequence 1: NP_649475.3
• Gene: sac / 40568
• FlyBaseID: FBgn0037254
• Length: 1079
• Species: Drosophila melanogaster
• Sequence 2: NP_001406479.1
• Gene: Dnah7 / 252893
• RGDID: 621798
• Length: 4023
• Species: Rattus norvegicus
• Alignment Length: 1031
• Identity: 181/1031 - (17%)
• Similarity: 370/1031 - (35%)
• Gaps: 228/1031 - (22%)

  Fly    73 YPIQEAQRWLTLMDKMGKAHRFPLPTILPKVIQTRYVPKRHLPKDVEVDRRRRQYQKINLVNELA 137
            |.::..|.:...|:..||..:     :|.::..||..|.....| |:...:.|:..:..|||.:.
  Rat    74 YNVKNEQSYAEYMEHFGKKGK-----LLDQIDDTRSAPSTSRSK-VKSPHKERENFRSTLVNVIM 132

  Fly   138 KAGLTDDVLQPTEEQYNVMSEFAFPHKFPLSYFDDSNFDINSPAAWFELGVVGDAHYPLPAKAYL 202
            :   .|..|:|     :|..|...| |...|..:.   ||.....:...|:..|...|:
  Rat   133 Q---QDSSLEP-----DVTDESGIP-KATTSAIEK---DILRYYYYIHHGIDTDNVAPM------ 179

  Fly   203 PYNQSLLNCQWGMAAVTAHHEDSDLWTLLSLEDGCTYTVPKLQFMFMAEDPHKYIKRLQAAV--- 264
                                |||.|..:|.|       ||            :::|.|..::
  Rat   180 --------------------EDSWLEHVLQL-------VP------------QHLKVLTNSITVL 205

  Fly   265 -HERHKGEQLMLMELIVDCVL---HEDIESTVFYSFKPIESVLQAAKVSEQCKRRLRSEVNLVFE 325
             .|..:...|.:.:.|||.||   .|..:.|......|..:.::.  :.:..:|...|..:.:.:
  Rat   206 SDEMREDYLLSVKKSIVDFVLKDPREKEDDTKITELPPHRAEMEV--LPKPWRRSFLSACSYIRD 268

  Fly   326 RLMALYELEQFILKM-PKEFPQFRNINLKEFLPRSFAVDVSGKERLELQALGITMQEKRYDYLKA 389
            .|.|:......:|.: ...|.:.|.::::||..|..|:::||.:.:.:
  Rat   269 HLNAMNPTMLAVLDLWHSTFKKLRLVDIEEFHNRQDALELSGFQNIVI----------------- 316

  Fly   390 SLFYCVGGIEAMAGVAIECQYIETLSIFICSFSKPLALVDFLQAQEAHSDNVATFLKVYWPQQLT 454
                               :::|:                   |:|       |.||.::|:
  Rat   317 -------------------KHMES-------------------AKE-------TLLKTWFPE--- 333

  Fly   455 TVITVVLRALGKGWLDISLNTWTVYLMCKISRFILQVKFRMQESMEVLLETSLMNFSHFVCDPCL 519
             |..:..:...|..|....::      .|:..|.......|...::.|:..|:.:|:..:..|
  Rat   334 -VQNIYYQGNKKKQLPTGDSS------AKLESFFNCAATLMTLQLQDLILVSMQDFTDLIAQP-- 389

  Fly   520 QFLELKSNYKWTNNYIDTEFPFQKPVFAMTLGISEDRKVFYSTDPDEFQPGLVEIFKKCLEKSSG 584
                           .::...|:.|.|.|.| :.:.:.|.:..:..::...||.:::..::..|.
  Rat   390 ---------------PESIRAFEHPGFIMRL-VLDKKAVKFEPEFTDYIDILVNVYEIMIKAVSF 438

  Fly   585 VRCIDGSVMSFLKFAPNLYILTVELIEDRFLRENELLKNCYAKAVLPLRAYARLYERFIDFYLLN 649
            |..::..:.|..:.......|...::::......|.::....:..:....:.::|:::.......
  Rat   439 VPRVETKLYSKWESKSKPTTLKPIILDEIIDAHKEKIREVVLRESVAPTEHLKMYDKYQFLITRQ 503

  Fly   650 VNTYMQAYAQAHKPSSEVKRDILENKRLKEELREILPAFITIGPFYINVDTMKQFMIKKRIEVVR 714
            ....::.:....:....:..:|.:.::|.||::......:.:|.|.::.:.:.:.::|:...:..
  Rat   504 AEQDIEEFLTQSQNYERLIEEIRKYQKLGEEIQYTSRKTVRLGMFEMHCEELIRSLVKRADIICG 568

  Fly   715 RIFEYYVDRMYETNEVLLDRCLEMFRRIAERPISIEHLYEIRDFAQTVPDLVD--ELKADIQ--- 774
            ::    :.:|:..::.:.....|.|.:|||:.:|            |.|:..:  |:||.||
  Rat   569 KL----IAKMFRDHQEVNTMLCEEFEKIAEKALS------------TPPNTAELMEMKAHIQKVE 617

  Fly   775 ---VMWLEYDLLDS-----FF---YNLSDHQFAMKWNVYAWPHQIMVRLSTLKDEQKVDIEDFLR 828
               ::.|...|:||     |.   .|.|.....:..:|:.|    ..|:..:.||.:..|:|...
  Rat   618 TTDMLDLGQRLVDSKNCLAFLIECVNFSPADIRLNNSVFQW----YGRMGEIFDEHRKIIKDKTE 678

  Fly   829 LHAS----ECQAFEERLESLNDEVQAYSLAFNTNRAQETSVDIKKTWALIKELEKVSQTL-QF-- 886
            .:..    .|:.|.|.|||...:.:.:   :.....|:....:||...|..:|:..:..: ||
  Rat   679 QYQEGLKLRCERFVEELESYAKQAEEF---YTFGDLQDVQRYLKKAQVLNSKLDAAADKIEQFNA 740

  Fly   887 RQELFELEPLSVEFLESIIASFTPYKNLWYGCANFLKLEDATLGNPI-------AQLDLEDVWNN 944
            .:|.|...|......:.|.....||..|:.....|.....|....|.       .:.|:.:.|..
  Rat   741 EEEAFGWIPSVYPQRKKIQDGLNPYLRLYETAVEFSTKHRAWTEGPYHKVNPDQVEADVGNYWRG 805

  Fly   945 LMRLRDELNESMKIFHEKVEIMDVAKTFIAKIDDFVPVYNSIKDIRNENWMYIHWQELSAITGQE 1009
            |.:|.       |.||:....:.:.|...|:::||......::.|.|......||:.:|||.|..
  Rat   806 LYKLE-------KAFHDSPNALAMTKKVRARVEDFKQYIPLVQVICNPGLRPRHWEAMSAIVGYP 863

  Fly  1010 IKYSVAMNYQYLIRKGILDVLPEVHIISEKANNEAEEIRRAIEEEERRKQAELNAM 1065
            ::.|........|...:...|.....|||.|:.|     .::|:...:...|..||
  Rat   864 LQPSDDSTVFSFIDMNLEPFLDRFEGISEAASKE-----YSLEKSMDKMMTEWEAM 914

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sac	NP_649475.3	DHC_N2	901..>1042	CDD:462462	33/147 (22%)
Dnah7	NP_001406479.1	DHC_N2	756..1161	CDD:462462	38/171 (22%)
		DYN1	958..3665	CDD:227570
		AAA_6	1289..1615	CDD:463697
		AAA_8	2310..2572	CDD:463701
		AAA_9	2960..3181	CDD:463702
		Dynein_C	3719..4019	CDD:465677