Protein Alignment sac and Dnah7b

DIOPT Version :10

• Sequence 1: NP_649475.3
• Gene: sac / 40568
• FlyBaseID: FBgn0037254
• Length: 1079
• Species: Drosophila melanogaster
• Sequence 2: NP_001355646.1
• Gene: Dnah7b / 227058
• MGIID: 2684953
• Length: 4024
• Species: Mus musculus
• Alignment Length: 1078
• Identity: 210/1078 - (19%)
• Similarity: 388/1078 - (35%)
• Gaps: 285/1078 - (26%)

  Fly    85 MDKMGKAHRFPLP-TILPKVIQTRYVPKRHLPKDVEVDRRRRQYQKI------NLVNELAKAGLT 142
            |||:....:..|| |:||::..|...|               |:|:|      |:..|
Mouse    26 MDKLSSREKDKLPTTVLPQLTSTGVKP---------------QWQQIAPSFHLNMKQE------- 68

  Fly   143 DDVLQPTEEQYNVMSEFAFPHKFPLSYF----------DDSNFDINSPAAWFELGVVGDAHYPLP 197
                .|..|.|.|.:|.:|...  :.||          ||..   :.|:       ...:....|
Mouse    69 ----NPILEPYPVKNEQSFADY--MEYFQQKGKQLYQIDDKR---SGPS-------TSRSKVKSP 117

  Fly   198 AKAYLPYNQSLLNCQWGMAAVTAHHEDSDLWTLLSLEDGCTYTVPKLQFMFMAEDPHKYIKRLQA 262
            .|....:..:|:.        ....:|.||.:.:..|.|    :||.......:|..:|...::.
Mouse   118 QKERENFRSTLVK--------LIMQQDGDLESDVIDESG----IPKATTTAREKDISRYYYYIRH 170

  Fly   263 AVHERHKGEQLMLMELIVDCVLHEDIESTVFYSFKPIESVLQAAKVSEQCKRRLRSEVNLVFERL 327
            .:...|....             ||         ..:|.|||   :..|..:.|.:.:.::.:.:
Mouse   171 GLDTDHVAPM-------------ED---------SWLEHVLQ---LVPQHLKILNNSIMVLSDEI 210

  Fly   328 MALYELEQFILKMPKEFPQFRNINLKEFLPRSFAVDVSGK------ERLELQALGITMQEKRYDY 386
            .     |.::|.:.|....|   .||:  ||.  .|..||      .|.|::.|   .:..|..:
Mouse   211 R-----EDYLLSVKKSIVDF---VLKD--PRK--KDDDGKITELPPHRAEMEVL---PKPWRRSF 260

  Fly   387 LKASLFYCVGGIEAMAGVAIECQYIE------------TLSIFICSFSKPLALVDFLQAQEAHS- 438
            |.|                  |.||.            .|.::..:|.| |.|||.   :|.|:
Mouse   261 LSA------------------CSYIRDHLNAMNPMMLAVLDLWHSTFKK-LRLVDI---EEFHNR 303

  Fly   439 -DNVATFLKVYWPQQLTTVITVVLRALGKGWLDISLNTW-----TVYL-------------MCKI 484
             |::          :|:....:|::.: :...::.|.||     .:|.             ..|:
Mouse   304 QDSL----------ELSEFQNIVIKHM-ESAKEMLLKTWFPEVQNIYYKGNKKKQLPTGKSSAKL 357

  Fly   485 SRFILQVKFRMQESMEVLLETSLMNFSHFVCDPCLQFLELKSNYKWTNNYIDTEFPFQKPVFAMT 549
            ..|.......|...::.|:..|:.:|:..:..|                 .::...|:.|.|.|.
Mouse   358 DSFFNCAATLMTLQLQDLILVSMQDFTDLIAQP-----------------PESTRAFEHPGFIMR 405

  Fly   550 LGISEDRKVFYSTDPDEFQPGLVEIFKKCLEKSSGVRCIDGSVMS--FLKFAPNLY--ILTVELI 610
            | |.:.:.:.::.|.:::...|:.:::..::..|.|..::..:.|  ..|..|...  |:..|:|
Mouse   406 L-ILDKKTIKFAPDFNDYIDILINVYEIMIKMVSFVPRVETKLYSQWESKSKPTTLKPIILNEII 469

  Fly   611 EDRFLRENELLKNCYAKAVLP---LRAYARLY-------ERFIDFYLLNVNTYMQAYAQAHKPSS 665
            :....:..|::   ..::|.|   |:.|.:..       ||.||.:|.....|           .
Mouse   470 DTHKEKIREVV---LRESVAPTEHLKMYDKYQFLITGKAERDIDEFLFQSQNY-----------E 520

  Fly   666 EVKRDILENKRLKEELREILPAFITIGPFYINVDTMKQFMIKKRIEVV--RRIFEYYVDRMYETN 728
            .:..:|.:.::|:||::......:.:|.|.::.:.:.:.:: ||.:|:  :.|.:.:.|.. |.|
Mouse   521 RLIEEIRKYQKLEEEIQYTSRKAVRLGMFEMHCEELIKSLV-KRADVICGKLIAKMFRDHQ-EVN 583

  Fly   729 EVLLDRCLEMFRRIAER----PISIEHLYEIRDFAQTVPDLVDELKADIQVMWLEYDLLDS---- 785
            .:|.|.    |.:|||:    |::...|.|::...|.: :..|.|:       |...|:||
Mouse   584 TMLCDE----FEKIAEKALSMPLNTAELMEMKAHVQKL-ETTDMLE-------LRQRLVDSKNCL 636

  Fly   786 -FF---YNLSDHQFAMKWNVYAWPHQIMVRLSTLKDEQKVDIEDFLRLHAS----ECQAFEERLE 842
             |.   .|.|.....:..:|:.|    ..|:..:.||.:..|:|....:..    .|:.|.|.||
Mouse   637 AFLIECVNFSPADIRLNNSVFQW----YGRMGEIFDEHRKIIKDKTEQYQEALKFRCERFVEELE 697

  Fly   843 SLNDEVQAYSLAFNTNRAQETSVDIKKTWALIKELEKVSQTL-QF--RQELFELEPLSVEFLESI 904
            |...:|:.:....:....|..   :||...|..:|:..:..: ||  .:|.:...|......:.|
Mouse   698 SYAKQVEEFHTFGDLLDVQRY---LKKAQVLNGKLDAAADKIEQFNAEEEAYGWVPSVYPQRKKI 759

  Fly   905 IASFTPYKNLWYGCANF-LKLEDATLG-----NP-IAQLDLEDVWNNLMRLRDELNESMKIFHEK 962
            .....||..|:.....| .|....|.|     || ..:.|:.:.|..|.:|.       |:||:.
Mouse   760 QDGLNPYLRLYETAVEFSTKHRGWTEGPYHKVNPDQVEADVGNYWRGLYKLE-------KVFHDS 817

  Fly   963 VEIMDVAKTFIAKIDDFVPVYNSIKDIRNENWMYIHWQELSAITGQEIKYSVAMNYQYLIRKGIL 1027
            ...:.:.|...:.:::|......|:.|.|......||:.:|.|.|..:..|........|...:.
Mouse   818 PNALAMTKKVQSMVEEFKQYIPLIQVICNPGLRPRHWEAMSTIVGFPLLPSDDSTVFSFIDMNLE 882

  Fly  1028 DVLPEVHIISEKANNEAEEIRRAIEEEERRKQAELNAM 1065
            ..|.....|||.|:.|     .::|:...:...|.::|
Mouse   883 PFLDRFEGISEAASKE-----YSLEKAMDKMMTEWDSM 915

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sac	NP_649475.3	DHC_N2	901..>1042	CDD:462462	34/147 (23%)
Dnah7b	NP_001355646.1	DHC_N2	757..1162	CDD:462462	38/171 (22%)
		DYN1	797..3666	CDD:227570	28/131 (21%)
		AAA_6	1290..1616	CDD:463697
		AAA_8	2311..2573	CDD:463701
		AAA_9	2961..3182	CDD:463702
		Dynein_C	3720..4020	CDD:465677