Protein Alignment sac and dnah6

DIOPT Version :10

• Sequence 1: NP_649475.3
• Gene: sac / 40568
• FlyBaseID: FBgn0037254
• Length: 1079
• Species: Drosophila melanogaster
• Sequence 2: XP_031759270.1
• Gene: dnah6 / 100487613
• XenbaseID: XB-GENE-6050691
• Length: 4161
• Species: Xenopus tropicalis
• Alignment Length: 1135
• Identity: 228/1135 - (20%)
• Similarity: 394/1135 - (34%)
• Gaps: 317/1135 - (27%)

  Fly    95 PLPTILPKVIQTRYVPK---------------RHLPKDVEVDRRRRQYQKI-------NLVNELA 137
            |||.:  ||.|..:.|:               .|.....|..:|....:.|       :|.::|.
 Frog    88 PLPVL--KVYQDHHQPEYIFQKNREELISRGVLHRSTSAEKGQRASSVEPISSPVRLPDLPDDLK 150

  Fly   138 KAGLTDD---VLQPTEEQYNVMSEFAFPHKFPLSYFDDSNF--DINS-PAAWFELGVVGDAHYPL 196
            :..|..|   ::.||            |.|.|.:....:|.  .::| |::.||     .|...:
 Frog   151 EKQLQLDFCRIISPT------------PPKQPRTALSSANSYKRLSSPPSSTFE-----TAEDVI 198

  Fly   197 PAKAYLPYNQSLL---NCQWGMAAVTAHHEDSDL-WTLLSLEDGCTYTVPKLQFMFMAEDPHKYI 257
            .||...|.....:   |...|...:|.....|.: :...:|.......:.|.::..|:|:...:|
 Frog   199 KAKISDPLQMIKIVQENKHLGFLYLTPAVPKSSIDYDTYNLRIATHQNINKNEYYTMSENGVTHI 263

  Fly   258 KRLQAAVHERHKGEQLML------MELIVDCVLHEDIESTVFYSFKPI---ESVLQAAKVSEQCK 313
            .          .||.|.|      .|.:....|.:.....:|..:|..   ...::|.:::| |:
 Frog   264 S----------DGEVLYLEIERWKQEYLYHKALKQIPTFALFRKWKAFTVWRKNVRAKRINE-CR 317

  Fly   314 RRLRSEVNLVFERL----------------MAL--------YELEQFILKMPKEFPQFRNINLKE 354
            :.|:..:.:|.|.|                |.|        |.|.:|.....|:..:..| .|.|
 Frog   318 KALQENLFIVNEYLRPAILNIQEMCYRISDMGLCRIEKEYTYSLHEFTGNQLKQLEEVAN-RLSE 381

  Fly   355 FLPRSFAVDVSGKE-RLELQALGITMQEKRYDYLKASLFYCVGGIEAMAGVAIECQYIETLSIFI 418
            |  |..|.:|.... |..|...|.|..|..:|.:      ..|.:...||.|:....:..|...:
 Frog   382 F--RDLAKEVVRSACRTALLEAGFTPDEYMHDQI------TTGFLSMTAGPAVSDMLLPHLDGEL 438

  Fly   419 CSFSKPLALVDFLQAQEAHSDNVATFLKVYWPQQLTTVITVVLRALGKGWLDISLNTWTVYLM-- 481
            ...|...........:.||...:..|:::   .....|.|:.:.|:.      |:||..:||:
 Frog   439 FGESSDKMTYTEQANKRAHCRRLTCFIRL---ADYLIVNTMHILAVN------SVNTLLMYLVEK 494

  Fly   482 --CKISRFILQVKFRMQESMEVLLETSLMNFSHFVCDPCLQFLELKSNYKWTNNYIDTEFPFQKP 544
              |..|..|  :|....:..|...|............|              ...|:.|.   .|
 Frog   495 LKCTPSDTI--IKTWNSQKQEASTEKKTTATQQLPIGP--------------GGQIEEEV---VP 540

  Fly   545 VFAMTLGISEDRKVFYSTDPDEFQPGLVEIFKKCLEKSSGVRCIDGSVMSFLKFAPNLYI----- 604
            :| :|..:.:.:.:::....|:||..:.|:..:..|          :|:|.....|:.|.
 Frog   541 MF-LTEIVLDTQALWFEPSLDDFQENIAEVVNQFQE----------TVLSLPNLVPDSYFDAFTK 594

  Fly   605 -----------------LTVELIEDRFLRE-----NELLKNCYAKAVLPLRAYARLYERFIDFYL 647
                             |:....:|:.|:.     .|.::..:..|    :.||..:|||:.|:.
 Frog   595 PTINNKLEEKTCGDGPTLSTMFDDDKHLQTIISQIKETIQYAFDAA----QVYAGTFERFLIFFK 655

  Fly   648 LNVNTYMQA-----------------YAQAHKPSSEVKRD------ILENKRLKEEL----REIL 685
            .|.|..::|                 |.:.|..:..:.::      :::.|:|||:|    :..|
 Frog   656 ENENLDLEAMKKEEPGVDFFAEKLEKYNKEHNDALAITQNRNIGLLLIDAKKLKEKLIPSPKRCL 720

  Fly   686 PAFITIGPFYINVDTMKQFMIKKRIEVVRRIFEYYVDRMYETNEVLLDRCLEMFRRIAERPISIE 750
            .|          ::.|...:.||:.:.|                            |||   :::
 Frog   721 EA----------INDMLPILAKKKTDAV----------------------------IAE---ALD 744

  Fly   751 HLYEIRDFAQTVPDLV------DELKADIQVMWLE-------YDLLDSFFYNLSDHQFAMKWNVY 802
            ..::::....|..|.|      ||::..|:|:..|       |.|:|::........||    ||
 Frog   745 AQFKLQSLPTTTIDYVNSLIFLDEIQERIEVLEEECNIVSHMYQLIDNYKVPTPPEDFA----VY 805

  Fly   803 A--WPHQIMVRLSTLKD--EQKVDIEDFLRLHASECQAFEERLESLNDEV----------QAYSL 853
            |  .|....||.:..|.  |:...||.|       |.:.::.:..||.||          |...|
 Frog   806 ATLQPSITAVRNAIDKSVGERDGSIEKF-------CHSLDKDIAELNKEVKEVRQKAQDPQILDL 863

  Fly   854 AFNTNRAQETSVDIKKTWALIKELEKVSQTLQFRQELFELEPLSVEFLESIIASFTPYKNLWYGC 918
            |.:..:.::...|:.   .::.||:..:...:..|:.|::|....|.||.:.|.....:.||...
 Frog   864 AADQVKVKQILADLH---TVLNELQTCAFQYKTYQKNFKVEVTKYEALEEVCAEVKLKQLLWDSL 925

  Fly   919 ANFLKLEDATLGNPIAQLDLEDVWNNLM--------RLRDEL--NESMKIFHEKVEIMDVAKTFI 973
            |.:..|:|..:.:....||.|.| |:|:        :|...|  |..:.:..||||.|
 Frog   926 AEWDVLQDEWMQSNFEALDPEQV-NSLVLKYAKFATQLEKGLPPNNVVPLLKEKVENM------- 982

  Fly   974 AKIDDFVPVYNSIKDIRNENWMYIHWQEL-SAITGQEIKYSVAMNYQYLIRKGILDVLPEVHIIS 1037
               .:.|||   |.|:||......||..| ..|....|.....::.|.||.....|....:..||
 Frog   983 ---KEKVPV---ITDLRNPFLKPRHWAALEQTINAALIDTEHPLSLQKLIEIHAFDYAQAIQDIS 1041

  Fly  1038 EKANNEA--EEIRRAIEEEERRKQAELNAM 1065
            .:|:.||  |.|.:.:|:.  .|..|..|:
 Frog  1042 GQASGEASLETIIKKVEDS--WKATEFTAI 1069

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sac	NP_649475.3	DHC_N2	901..>1042	CDD:462462	41/151 (27%)
dnah6	XP_031759270.1	DHC_N2	908..1320	CDD:462462	49/178 (28%)
		DYN1	<1148..3779	CDD:227570
		AAA_6	1455..1781	CDD:463697
		Dynein_C	3831..4157	CDD:465677