Protein Alignment sac and dnah1

DIOPT Version :10

• Sequence 1: NP_649475.3
• Gene: sac / 40568
• FlyBaseID: FBgn0037254
• Length: 1079
• Species: Drosophila melanogaster
• Sequence 2: XP_009304459.3
• Gene: dnah1 / 100317899
• ZFINID: ZDB-GENE-081015-3
• Length: 4175
• Species: Danio rerio
• Alignment Length: 1010
• Identity: 270/1010 - (26%)
• Similarity: 490/1010 - (48%)
• Gaps: 87/1010 - (8%)

  Fly   101 PKVIQTRYV-PKRHLPKDVEVDRRRRQYQKINLVNELAKAGLTDDVLQPTEEQYNVMSEFAFPHK 164
            ||| |..|: |..|:|:.:|::||||:|||:::...|::.|:..:.|.|:.:..........|:.
Zfish   116 PKV-QLPYICPPGHVPRKIEIERRRREYQKLDISKLLSEQGINSNQLIPSNQTRTETKNQPDPNY 179

  Fly   165 FPLSYFDDSNFDINSPAAWFELGVVGDA--HYPLPAKAYLPYNQSL---------LNCQWGMAAV 218
            ..|..||:..||..:|..|..||....:  ..|:||||.||...|:         :...|....|
Zfish   180 LSLEIFDNEEFDCRTPEEWLALGYEPGSMNRKPIPAKALLPTKNSIPPVDPQSPAVEYSWQSVGV 244

  Fly   219 ----------TAHHEDSDLW-----------------TLLSLEDGCTYTVPKLQFMFMAEDPHKY 256
                      ..|..|.:.|                 .||..:    |.||:::.:|.||||..:
Zfish   245 LRYSQEKKQYLVHKADCNGWVRDFMGNPILNGGQREGVLLESQ----YWVPRIRLLFCAEDPRVF 305

  Fly   257 IKRLQAAVHERHKGEQLMLMELIVDCV----LH-EDIESTVFYSFKPIESVLQAAKVSEQCKRRL 316
            .:|:|.|.:.|...|...|....|||:    || ..:|....|:..  .|.|| .|..::|:::|
Zfish   306 AQRVQFAENLRQNTEASNLYHHSVDCMPVWHLHPTSLERIRKYALS--TSGLQ-LKCLQECEKQL 367

  Fly   317 RSEVNLVFERLMALYELEQFIL-KMPKEFPQFRNINLKEFLPRSFAVDVSGKERLELQALGITMQ 380
            ..|:||.:.|     .|.|... |:.::.|:  :|.|.:..|.|.      .||..:.......:
Zfish   368 EKELNLEYSR-----TLNQMCFNKVVQDKPE--DITLPQTQPESI------PERGFVSVPNYPFE 419

  Fly   381 EKRYDYLKASLFYCVGGIEAMAGVAIECQYIETLSIFICSFSKPLALVDFLQAQEAHSDNVATFL 445
            :.|..::..||......|..::.|..||..:..:|:|..||:|.|.|.:|..||......:..||
Zfish   420 KNRAAFVFNSLLTKAEVIAVLSRVREECNRVAEMSLFYVSFTKSLRLEEFESAQSQKHSQIHLFL 484

  Fly   446 KVYWPQQLTTVITVVLRALGKGWLDISLNTWTVYLMCKISRFILQVKFRMQESMEVLLETSLMNF 510
            :..|...|...|:..||.....|.:::::...||.|.|:.|.:..::...|:|:..|::.||.:.
Zfish   485 EESWLPALCNGISSNLRDERCSWYNLAVSRCDVYRMSKLCRLMALIRSLQQDSLRFLVQGSLASL 549

  Fly   511 SHFVCDPCLQFLELKSNYKWTNNYIDTEF-PFQKPVFAMTLGISEDRKVFYSTDPDEFQPGLVEI 574
            :..:.|.|...|:......|..:.|::.: |.:||:|::.| :.:...|.|||..:.|:..::.:
Zfish   550 TKLILDACHSVLQCPQELTWGPDLINSPYKPKKKPLFSVDL-VLDQTGVHYSTPLESFETSVINL 613

  Fly   575 FKKCLEKSSGVRCIDGSVMSFLKFAPNLYIL-----TVELIEDRFLRENELLKNCYAKAVLPLRA 634
            |.|.:..:..|..:|..|:      |||:|:     :|.|.|.......|.:.....:|::||:|
Zfish   614 FDKGILSTHNVPQVDKFVL------PNLFIVGEVLWSVGLWEPEVKNLRESISKALKQAIIPLKA 672

  Fly   635 YARLYERFIDFYLLNVNTYMQAYAQAHKPSSEVKRDILENKRLKEELREILPAFITIGPFYINVD 699
            |.|.||.:::.|..:||||::.::|.::...|||:::||:....|.|.:.:|:.|.||||.:||:
Zfish   673 YTREYECYLELYNSDVNTYLELHSQENQTPQEVKQEVLEHLMEVEHLNKSIPSAIIIGPFMVNVE 737

  Fly   700 TMKQFMIKKRIEVVRRIFEYYVDRMYETNEVLLDRCLEMFRRIAERPISIEHLYEIRDFAQTVPD 764
            .::|.::|||..:.:.:.:....|:.:..:.....|..:.:::.|:|.|||.|.|.|::...||
Zfish   738 AIRQSLVKKRKGLAKALLDRLALRLRQQMQDACKECKAISKKLFEKPSSIEELTEQREWMNQVP- 801

  Fly   765 LVDELKADIQVM---WLEYDLLDSFFYNLSDHQFAMKWNVYAWPHQIMVRLSTLKDEQKVDIEDF 826
              ::|||..:::   ..:|||:|.|:|:|||.:|..||:..||||:|:.::.|:..:...|.|.|
Zfish   802 --EQLKAHEEILSKAMSDYDLIDEFYYSLSDEEFKEKWSAMAWPHKILTQMETVSAQHVDDEERF 864

  Fly   827 LRLHASECQAFEERLESLNDEVQAYSLAFNTNRAQETSVDIKKTWALIKELEKVSQTLQFRQELF 891
            .::..::..:|.|||..|...|..:|...|..||.|.:.::::....:||.::::|....|:.||
Zfish   865 DKIQVADQNSFLERLSFLEMVVAGFSGYTNLERAHEVANEVRRVGKQLKECQEMAQLYNNRERLF 929

  Fly   892 ELEPLSVEFLESIIASFTPYKNLWYGCANFLKLEDATLGNPIAQLDLEDVWNNLMRLRDELNESM 956
            .....:...|:.:...|.|:.:||...:::|:..::.|.:|:|.::.|.:..|:......:::.:
Zfish   930 GKPVTNYTELQKLNRDFQPFHDLWKTTSDWLRWHESWLNDPLAAINPEQLERNVTDAYKTMHQCV 994

  Fly   957 KIFHEKVEIMDVAKTFIAKIDDFVPVYNSIKDIRNENWMYIHWQELSAITGQEIKYSVAMNYQYL 1021
            |.|.:.....:||.....||:.|.|....|:.:||......||:.||......::....:.:...
Zfish   995 KQFKDLPACQEVASEIRTKIEAFRPFIPLIRSLRNPGMRNRHWELLSERININMRSRANLTFSLC 1059

  Fly  1022 IRKGILDVLPEVHIISEKANNE--AEEIRRAIEEE 1054
            :..|:.|.:.|:..::::|..|  .|:....:|||
Zfish  1060 LELGLQDHVEEITRVAQEAGKEYSIEQALNKMEEE 1094

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sac	NP_649475.3	DHC_N2	901..>1042	CDD:462462	30/140 (21%)
dnah1	XP_009304459.3	DHC_N2	939..1342	CDD:462462	35/156 (22%)
		DYN1	1120..3808	CDD:227570
		AAA_6	1468..1794	CDD:463697
		Dynein_C	3869..4171	CDD:465677