DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31522 and ELOVL3

DIOPT Version :9

Sequence 1:	NP_001262254.1	Gene:	CG31522 / 40567	FlyBaseID:	FBgn0051522	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_689523.1	Gene:	ELOVL3 / 83401	HGNCID:	18047	Length:	270	Species:	Homo sapiens

Alignment Length:	264	Identity:	70/264 - (26%)
Similarity:	111/264 - (42%)	Gaps:	48/264 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 SSPFPTLAVCLTYVYLVKVLGPRLMENRKPLNLQNTLVMYNAIQVVFSAWLFYECLMGGWWGSYS 94
            ::.||   :.|.|:.|:.| |...|:.||..|||..|::::....:||       ::|
Human    35 ATSFP---IALIYLVLIAV-GQNYMKERKGFNLQGPLILWSFCLAIFS-------ILG------- 81

  Fly    95 FRCQPVDYTDSPTSRRIGISG--WLTGHYSFRCQPVDYSNNPRTLRMVHACWWYYFSKFTEFMDT 157
                        ..|..||.|  .|||...   |.|.:.|......:....|.:..||..|..||
Human    82 ------------AVRMWGIMGTVLLTGGLK---QTVCFINFIDNSTVKFWSWVFLLSKVIELGDT 131

  Fly   158 IFFVLRKKSSQVTTLHVIHHGCMPMSVWFGVK-FTPGGHSTFFGLLNTFVHIVMYTYYMFSAMGP 221
            .|.:|||:  .:..:|..||..:.:...||.| ..|.|  .:|..:|..||.:|||||...|...
Human   132 AFIILRKR--PLIFIHWYHHSTVLVYTSFGYKNKVPAG--GWFVTMNFGVHAIMYTYYTLKAANV 192

  Fly   222 QYQKYLWWKKYLTTLQMVQFILIMVHAFQLLFI-----DCNYPKAFVWWIGMHAVMFFFLFNEFY 281
            :..|.|  ...:|:||::|..:..:.:. |.:|     .|:.....::|..:..:.:|.||..|:
Human   193 KPPKML--PMLITSLQILQMFVGAIVSI-LTYIWRQDQGCHTTMEHLFWSFILYMTYFILFAHFF 254

  Fly   282 KAAY 285
            ...|
Human   255 CQTY 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31522	NP_001262254.1	ELO	27..293	CDD:279492	70/264 (27%)
ELOVL3	NP_689523.1	ELO	29..266	CDD:307345	70/264 (27%)
ELOVL3	NP_689523.1	Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03203	266..270
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820