DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31522 and Elovl7

DIOPT Version :9

Sequence 1:	NP_001262254.1	Gene:	CG31522 / 40567	FlyBaseID:	FBgn0051522	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_083277.3	Gene:	Elovl7 / 74559	MGIID:	1921809	Length:	281	Species:	Mus musculus

Alignment Length:	317	Identity:	148/317 - (46%)
Similarity:	184/317 - (58%)	Gaps:	51/317 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 MKYIDSIS---RYMDS---HSDSRTKGWPMMSSPFPTLAVCLTYVYLVKVLGPRLMENRKPLNLQ 63
            |.:.|..|   |:.|:   .:|.|.:.:.:||||.|...:...|||.|..|||:|||||||..|:
Mouse     1 MAFSDLTSRTVRFYDNWIKDADPRVEDYLLMSSPLPQTIILGLYVYFVTSLGPKLMENRKPFELK 65

  Fly    64 NTLVMYNAIQVVFSAWLFYECLMGGWWGSYSFRCQPVDYTDSPTSRRIGISGWLTGHYSFRCQPV 128
            ..::.||...|:||.::.||.:|                           |||.|| |||||..|
Mouse    66 KAMITYNFFIVLFSVYMCYEFVM---------------------------SGWGTG-YSFRCDIV 102

  Fly   129 DYSNNPRTLRMVHACWWYYFSKFTEFMDTIFFVLRKKSSQVTTLHVIHHGCMPMSVWFGVKFTPG 193
            |||.:||.:||||.||.||||||.|.:||||||||||:||||.|||.||..||.:.||||||..|
Mouse   103 DYSQSPRAMRMVHTCWLYYFSKFIELLDTIFFVLRKKNSQVTFLHVFHHTIMPWTWWFGVKFAAG 167

  Fly   194 GHSTFFGLLNTFVHIVMYTYYMFSAMGPQYQKYLWWKKYLTTLQMVQFILIMVHAFQLLFI-DCN 257
            |..||...|||.||:|||:||...||||.|||||||||:||:||:|||:|:.:|..|:.|: |||
Mouse   168 GLGTFHAFLNTAVHVVMYSYYGLCAMGPAYQKYLWWKKHLTSLQLVQFVLVTIHIGQIFFMEDCN 232

  Fly   258 YP-KAFVWWIGMHAVMFFFLFNEFYKAAYRSRMMKKNGALANGHAKP----NGYCKS 309
            |. ..|::.|..:..:|..||..|:..||           ..|...|    ||.|||
Mouse   233 YQYPVFLYIIMSYGCIFLLLFLHFWYRAY-----------TKGQRLPKTLENGNCKS 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31522	NP_001262254.1	ELO	27..293	CDD:279492	134/267 (50%)
Elovl7	NP_083277.3	ELO	30..269	CDD:279492	135/277 (49%)
Elovl7	NP_083277.3	Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03207	277..281		2/2 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837634
Domainoid	1	1.000	275	1.000	Domainoid score	I1738
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I2754
Isobase	1	0.950	-	0	Normalized mean entropy	S2719
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	1	1.000	-	-		mtm8792
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11157
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R389
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840