DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14650 and SARNP

DIOPT Version :9

Sequence 1:	NP_649473.1	Gene:	CG14650 / 40566	FlyBaseID:	FBgn0037252	Length:	970	Species:	Drosophila melanogaster
Sequence 2:	NP_149073.1	Gene:	SARNP / 84324	HGNCID:	24432	Length:	210	Species:	Homo sapiens

Alignment Length:	180	Identity:	40/180 - (22%)
Similarity:	68/180 - (37%)	Gaps:	32/180 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   239 EANEMDVVLETSIAQQPQVPNQNLQQPEPLSQSVNTLPAASKPAKSLKMPLATATVSPTAINKSS 303
            ||||.||:.:.:..::.:.....:::.||..::|:.  ||.|     |:...|:.:..|...:..
Human    49 EANEEDVLGDETEEEETKPIELPVKEEEPPEKTVDV--AAEK-----KVVKITSEIPQTERMQKR 106

  Fly   304 VA---VPGQPEGKKRIVAEVKPMPMSYSDVLSKGTKPSAAGRDMRADNGGDYSVQSQRRPEKEDA 365
            ..   ||...|.||    ..:......|.|.:||         :.:||  ...|...:..|:...
Human   107 AERFNVPVSLESKK----AARAARFGISSVPTKG---------LSSDN--KPMVNLDKLKERAQR 156

  Fly   366 YGNREMRTSKRS----PLHDAKETGSFV---PGVGHAHASRGKKRSKVSQ 408
            :|......|::|    .|...||....|   .|.|....:..|||.:..:
Human   157 FGLNVSSISRKSEDDEKLKKRKERFGIVTSSAGTGTTEDTEAKKRKRAER 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14650	NP_649473.1	DnaJ	708..769	CDD:278647
CG14650	NP_649473.1	Jiv90	802..891	CDD:291562
SARNP	NP_149073.1	PLN03124	7..>90	CDD:215591	12/47 (26%)
		SAP	8..42	CDD:128789
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	45..86		9/38 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..210		11/46 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0720
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900