Protein Alignment CG14650 and LOC1273576

DIOPT Version :10

• Sequence 1: NP_649473.1
• Gene: CG14650 / 40566
• FlyBaseID: FBgn0037252
• Length: 970
• Species: Drosophila melanogaster
• Sequence 2: XP_312569.6
• Gene: LOC1273576 / 1273576
• VectorBaseID: AGAMI1_004602
• Length: 1077
• Species: Anopheles gambiae
• Alignment Length: 1115
• Identity: 412/1115 - (36%)
• Similarity: 546/1115 - (48%)
• Gaps: 230/1115 - (20%)

  Fly    23 PHTDEVGNYLAHQQQQQQQQQHQHQTQNYLIHQQ-----QH---GQAPVPLMWPPPPPH------ 73
            ||     :|.||.|.|..||.||...|..::..|     ||   ....||::.|...|:
Mosquito    26 PH-----HYAAHAQHQFHQQLHQTLLQQPVVPPQLLPHPQHLSYAVPTVPVVAPSGAPYYHGAAG 85

  Fly    74 ------LAGPPFAPHLQQQQPHMYNEY------LFNLSYSGQPGQPETYSVLPVGPGNFLKVYHC 126
                  .:|..|:.|....|| :.:||      ...:.|..|..|....:.....||........
Mosquito    86 MVDGYGASGTGFSMHHGAHQP-LEDEYSDAYGQAIKVVYQPQQHQASAVTAAAAAPGMMPCTQED 149

  Fly   127 PD-NQV--SEAGTPLFTHINMASI---------------NHHQLQHQHQAAPPTPSQPTPLYELF 173
            |: |.|  .:.|..||:  |.:|.               ...|.|.|.|..|....||...:...
Mosquito   150 PNQNHVVQDKQGYELFS--NNSSFMLAAPGFGFTLHNPQQQQQQQQQQQEQPQQQQQPMSQFSSM 212

  Fly   174 ATNPLTLPHAQQQDAQHRQPQQTQTQAPTVSQVNHSSSSANLLINNLVNNWSPNLT-----GGSY 233
            :|.|..:.|..|| |....||.|.:|  |:...|:|:||   ||:.||.||:|.::     |.|.
Mosquito   213 STPPAQVTHPTQQ-AAAPVPQATTSQ--TLENGNNSTSS---LISQLVGNWAPTISGTYGNGPSS 271

  Fly   234 IQFDG-----------EANEMDVVLETSIAQQPQVPNQNLQQPEPLSQSV--NTLPAASKPAKSL 285
            :..|.           |.|....|..|.:|....|.|       |::.:|  .|..|...|:.|
Mosquito   272 LANDAPSQSVSNPPVQEDNSKATVSPTKVAFSKPVIN-------PVTPNVIGTTSQAHGSPSSS- 328

  Fly   286 KMPLATATVSPTAINKSSVAVPGQPEG------------KKRIVAEVKPMPMSYSDVLSK----- 333
              |.....||....|.::.||..|...            |:|||||||||.|||||||||
Mosquito   329 --PSVVPAVSSNRNNTNAAAVYNQQNDDNSAKLDQNVNKKQRIVAEVKPMRMSYSDVLSKNVPSG 391

  Fly   334 ------------------------GTKPSAAGRDMRADNGGDYSVQSQRRPEKEDAYGNREMRTS 374
                                    |||.|.:|    ..|||. ..:|:|..::.:|.|.|:...:
Mosquito   392 GNPFASNASTNGEMVSALPATFGNGTKVSGSG----GPNGGS-GGKSKRESKRSNANGERKSMGN 451

  Fly   375 KRSPLHDAKET---------------------------GSFVPGVGHAHAS----RGKKRSKVSQ 408
            ..:..| ||:.                           ||..|..|.|.|:    :.|.|:|..:
Mosquito   452 AGNVTH-AKDRANDGSTRKADRTNGAGTGTNSPTMTDGGSSKPMEGSADATLRSGQEKGRNKSDK 515

  Fly   409 TAPLKVQQ--SQSLAQPNLQ---PQIKSNKLNNPEKKRPLQPKNVNSNAPKFSEHKTTPVSANSS 468
            |:.:|..:  |:|.|: .|:   .:.:|...:|.::...||  |..|:|      .:.|: ||..
Mosquito   516 TSGVKRDKGGSRSGAE-GLETGGKKGRSGTHSNEDETGGLQ--NCRSDA------SSAPL-ANDE 570

  Fly   469 LQNH---------SNVLNFTPATNSSTSSRKSGSNKINSNASH----------SNHTGAN-THAG 513
            ::..         |:..:.....:|.||.|:....:....|.|          .|..||| ||..
Mosquito   571 MEEERGEDYEEYDSDEYDQVSIGSSETSGRQDKQQQQQHQAGHEELPFLYNVKKNTNGANDTHIE 635

  Fly   514 SSSSSSSVNYSSNNNVSSSSAKRYSSSNLNPNNSSGYSYSS-KRN-RSNAYSSTNSPTHANSFSS 576
            ..:...:...|::.......:.|  :....|:.|.|...:| ||: ||.               .
Mosquito   636 KINPPRTATASTHRKGGGGRSAR--APGKQPDKSVGNQQASGKRSVRSR---------------K 683

  Fly   577 NRNYELAKRIIHTWWIYTLKLLTWLFYLVYDIVVLGFSMGYERITLAYVAALAYARQLQKELKQN 641
            |:.|...::::..|..||:..|.||:.||.|:|.|...:.::.:..||.....:...::::..:|
Mosquito   684 NQKYAFLEKLLLKWLEYTMLALHWLWSLVSDVVYLSARLAWDYVLSAYQYCRQHVHTIRQDFGKN 748

  Fly   642 SGKPSIWWRSYWRRFDARFAKNSRLAVWRLFYKRK---PPETTSEQFKTGRLPQTGEEAMYSLLN 703
            ||:|..|:|..|:.||..|||.||.|.||...|:|   ||...|..::.||||.|.:|||.||||
Mosquito   749 SGRPGAWFRRVWQSFDGHFAKESRWAFWRRCRKQKPAEPPGGKSTPYRDGRLPSTADEAMSSLLN 813

  Fly   704 CKGKDAYSILGVPPDSSQEQIRKHYKKIAVLVHPDKNKQAGAEEAFKVLQRAFELIGEPENRLIY 768
            ||||||||||||.||.|||||||||||||||||||||||.|||||||||||:||||||||:|..|
Mosquito   814 CKGKDAYSILGVSPDCSQEQIRKHYKKIAVLVHPDKNKQPGAEEAFKVLQRSFELIGEPESRKEY 878

  Fly   769 DQSIAETLHTEKAWTELHDLLSQLQTKMAEAANTIRCSTCAQRHPRKLTERPHYAARECASCKIR 833
            |||:||.|:.||||:|::|||:||.||::|||||||||:|..|||||.|.|.|||||||:|||||
Mosquito   879 DQSLAEALNAEKAWSEINDLLTQLHTKISEAANTIRCSSCCLRHPRKPTGRAHYAARECSSCKIR 943

  Fly   834 HSAKDGDIWAETSMMGLRWKYLALMDGKVYDITEWANCQKGALSHLEPNSHMVQYRIVRGAQQQQ 898
            |.|::||||||||.:||||||||:|:|.||||||||||||||||||:||||:||||||.|:..||
Mosquito   944 HPAREGDIWAETSFLGLRWKYLAMMEGNVYDITEWANCQKGALSHLQPNSHIVQYRIVLGSSSQQ 1008

  Fly   899 QQQQQQQQQQQQQHHQHPQQPHHD---RGVHHPGGGVSGVSEATLHEFLDNLYSGQHPGAHNAFA 960
            ||||||||||.|..||..|....|   |....|     ..:|..|.:||:|:|:||:..|.:..|
Mosquito  1009 QQQQQQQQQQHQPQHQAGQPLDKDQIGRSRKEP-----TANEPNLDDFLNNIYAGQNQQASSQNA 1068

  Fly   961 GNARRRTRRN 970
             ::|||.|||
Mosquito  1069 -SSRRRYRRN 1077

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14650	NP_649473.1	DnaJ	708..769	CDD:395170	53/60 (88%)
		Jiv90	800..891	CDD:464360	73/90 (81%)
LOC1273576	XP_312569.6	None