DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14650 and AgaP_AGAP007541

DIOPT Version :9

Sequence 1:	NP_649473.1	Gene:	CG14650 / 40566	FlyBaseID:	FBgn0037252	Length:	970	Species:	Drosophila melanogaster
Sequence 2:	XP_308338.4	Gene:	AgaP_AGAP007541 / 1269693	VectorBaseID:	AGAP007541	Length:	681	Species:	Anopheles gambiae

Alignment Length:	349	Identity:	72/349 - (20%)
Similarity:	125/349 - (35%)	Gaps:	105/349 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   651 SYWRRFDARFAK-NSRLAVWRLFYKRKP-----PETTSEQFKTGRLP-QTGE--------EAMYS 700
            :|.||..|...| :..|...:..::.:|     |.|..|...:|.|| ..|:        ||::.
Mosquito    24 NYDRRRSAAGTKWDETLEYLQYLHETQPIVPKCPPTKDELIASGALPADAGQNAPAAVDPEALFE 88

  Fly   701 LL--------------NCKGKDAYSILGVPP---DSSQEQIRKHYKKIAVLVHPDKNKQAGA--- 745
            .|              :.|.:|.|.:||:..   .::.|.|::.|:||.:..||||.|..|.
Mosquito    89 ELFAVDIDYLKSLDPKDWKNQDHYHVLGLNKMRFTATDEDIKRAYRKIVLKHHPDKRKALGENVK 153

  Fly   746 --EEAFKVLQRAFELIGEPENRLIYDQ---------------------SIAETLHTEKAWTELHD 787
              ::.|..:..|:|.:|..:||..:|.                     |:|:.......|.|
Mosquito   154 QDDDYFHCITMAYETLGTVKNRRAFDSIDPEFDDSLPSQAEVEKDFFGSLADVFKRNARWNE--- 215

  Fly   788 LLSQLQTKMAEAANTIRCSTCAQRHPRKLTERPHY--------AARECASCKIRHSAKDGD---- 840
              |:....:....||          ||:..|  |:        :.||.:........|..|
Mosquito   216 --SRKAAPLLGDDNT----------PREAVE--HFYDFWYNFQSWREFSYLDEEDKEKGQDREER 266

  Fly   841 IWAETSMMGLRWK--------YLALM------DGKVYDITEWANCQKGALSHLEPNSHMVQ---- 887
            .|.|.....:|.|        ..||:      |.:|.........:|.|....:..::.||
Mosquito   267 RWIEKQNKAIRLKRKKEESARIRALVDLAYNNDPRVVRFKREEKERKLAAKRAKQTAYQVQKAEE 331

  Fly   888 YRIVRGAQQQQQQQQQQQQQQQQQ 911
            .|:.:.|.:.:|:.::.:|::.:|
Mosquito   332 ERVAKEAAEAKQRAEEAEQKRIEQ 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14650	NP_649473.1	DnaJ	708..769	CDD:278647	21/68 (31%)
CG14650	NP_649473.1	Jiv90	802..891	CDD:291562	22/118 (19%)
AgaP_AGAP007541	XP_308338.4	ZUO1	72..427	CDD:227594	59/301 (20%)
		DnaJ	110..179	CDD:278647	21/68 (31%)
		RAC_head	367..432	CDD:293322
		SANT	618..667	CDD:197842
		SANT	620..667	CDD:238096
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910