Protein Alignment CG14650 and kiaa1614

DIOPT Version :9

• Sequence 1: NP_649473.1
• Gene: CG14650 / 40566
• FlyBaseID: FBgn0037252
• Length: 970
• Species: Drosophila melanogaster
• Sequence 2: XP_002937008.2
• Gene: kiaa1614 / 100497220
• XenbaseID: XB-GENE-6467981
• Length: 1068
• Species: Xenopus tropicalis
• Alignment Length: 1025
• Identity: 193/1025 - (18%)
• Similarity: 311/1025 - (30%)
• Gaps: 376/1025 - (36%)

  Fly     3 TRQDDEIGGGSTESAPFRV-LPHTDEVGN---YLAHQQQQQQQQQHQHQTQNYLIHQ---QQHGQ 60
            :|||..:..|:.......| ||  |..||   .:.|:|.:|            |:|:   :..|.
 Frog   227 SRQDSWLVPGADADCDSGVSLP--DPEGNRELSIRHEQAKQ------------LLHRARMKAKGA 277

  Fly    61 APVPLMWPPPPPHLAGPPFAPHLQQQQPHMYNEYLFNLSYSGQPGQPETYSVLPVGPGNFLKVYH 125
            :|:.......|..|:..|     ||:.|.:........|.|...|..                 |
 Frog   278 SPLRASHCVLPHALSQLP-----QQRGPCVSGAVTDGGSLSDSSGSD-----------------H 320

  Fly   126 CPDNQVSEAGTPLFTHINM-----ASINHHQLQHQHQAAPPTPSQPTPLYELFATNPLTLPHAQQ 185
            |..::.|...:|  :|:..     ..:.....:.|.|..|.....||       |.|....:...
 Frog   321 CSWHRSSRGSSP--SHVRFQDESERDVEERYRERQQQGPPSAGISPT-------TPPARRSNGHV 376

  Fly   186 QDAQHRQPQQTQTQAPT---------VSQVNHSSSSANLLINNLVNNWSPNLTGGSYIQFDGEAN 241
            ...||..|...:.|..|         |.:.|..:.||.   :||   |:.:|  ||.|..||..|
 Frog   377 SWTQHLVPFGNENQCGTCGSYIKGSGVQRQNLEAYSAG---SNL---WNVHL--GSRISQDGSIN 433

  Fly   242 EMDVVLETSIAQQPQVPNQNLQQPEPLSQSVNTLPAASKPAKSLKMPLATATVSPTAINKSSVAV 306
            .                                 |..:||             ||..|      :
 Frog   434 S---------------------------------PLGTKP-------------SPHWI------L 446

  Fly   307 PGQPEGKKRIVAEVKPMPMSYSDVLSKGTKPSAAGRDMRADNGGDYSVQSQRRPEKEDAYGNREM 371
            |.||   .|:.:|:              .:.:..|.|..||:.|:..|             ||..
 Frog   447 PSQP---WRVHSEL--------------IRETHIGGDSTADSSGEDEV-------------NRAQ 481

  Fly   372 RTSKRS--PLHDAKETGSFV-PGVGHAHASRGKKRSKVSQTAPLKVQQSQSLAQPNLQPQIKSNK 433
            :.|.|:  ||..:|.....| ||.| |..|..:...| |.|:.|.:.....:::.|  |:.::..
 Frog   482 KKSCRTLGPLRSSKNKQHNVEPGSG-ARTSLPQSEIK-SSTSALMIDPRTKISESN--PETETAV 542

  Fly   434 LNNPEKKRPLQPKNVNSNAPKFSEHKTTPVSANSSLQNHSNVLNFTPATNS-------------- 484
            |.|.........|.|   |..::|.:||....|:.|:..:..|:.:|...:
 Frog   543 LGNLHNTNIKLEKQV---AVHYTEPRTTLNPTNAPLKFGNECLDASPNPGALTIHGHVPVPPAGK 604

  Fly   485 --STSSRKSGSNKINSNASHSNHTGANTHAGSSSS----------SSSVNYSSNNN--------- 528
              |..:.:||...:.|..:. :|....|..|.:..          |.:|..:.|..
 Frog   605 APSAGTPRSGRFAVRSEGAF-HHLPVGTSHGENMEQVIVIEKGIPSDTVPKNKNQEKLRVSDIHP 668

  Fly   529 VSSSSAK-----------------------RYSSSNL-NPNNSSGYS------------YSSKRN 557
            :|.|..|                       |....|| .|:.::|.:            ||.::|
 Frog   669 LSLSEIKMKEEGRERTQKVKKLIKKEKPNERQEQRNLEGPDVTNGQAESERAHKSLRQRYSDRKN 733

  Fly   558 RSNAYSST----NSPTHAN-SFSSNRNYELAKRI-------IHTWWIYTLKLLTWLFYLVYDIVV 610
            .|....:|    .|..||: :.|...|:.|.|.|       |:....:|
 Frog   734 ASKEQRNTEVTQTSGDHADRAVSDLLNHHLVKEINNGKREHINAQRSFT---------------- 782

  Fly   611 LGFSMGYERITLAYVAAL--------------AYARQLQKE--------LKQNSGKPSIWWRSYW 653
             |..:.:|......|:|.              .:.|||.:|        ..::|.:|:.
 Frog   783 -GGDVQHESTDSVDVSASEVGSAFCGATLEHPVHDRQLDQESGDVNQCVTHKSSMQPAA------ 840

  Fly   654 RRFDARFAKNSRLAVWRLFYKRKPPETTSEQFKTGRLPQTGEEAMYSLLNC----------KGKD 708
            ||.|.|......|:.:.|..:.|     .|:|::..|.|....|..|...|          .|||
 Frog   841 RRGDIRSGMKKILSSFGLASRPK-----LERFQSSSLEQIFTPAAGSSGACVGGNKERCEDAGKD 900

  Fly   709 AYSILGVPPD----------------SSQEQIRKHYKKIAVLVHPDKN---------KQAGAEEA 748
            ..  |...|.                ||.:.:....::.||.:..|.|         :..|:...
 Frog   901 GR--LKKSPSLQSLKLVTQFHLPRKASSVQNLLGKSERSAVYLTEDANTAPRRALSVEDIGSPGM 963

  Fly   749 FKVLQRAFELI-------------------------GEPENRL-IYDQSIAETLHTEKAWTELHD 787
            .:||.|..|:.                         |.|::.: :.:.|.|.|.....:...:.|
 Frog   964 PRVLGRVAEVYPDGTRLLQLQRPPQGSFGFSISSVNGRPDSGIYVQEMSDASTAKLFSSLLRVGD 1028

  Fly   788 LLSQLQTKMAEAANTIRCSTCAQRHPRKLTERPHYAARECASCKIRHSAK 837
            .:.:|        |..:.||.|.....|:.:|     ....|.::.|..:
 Frog  1029 EILEL--------NGTKVSTIAHEQLSKIMDR-----ESTLSLRVLHQRR 1065

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14650	NP_649473.1	DnaJ	708..769	CDD:278647	16/111 (14%)
		Jiv90	802..891	CDD:291562	7/36 (19%)
kiaa1614	XP_002937008.2	DUF4685	247..355	CDD:374064	27/145 (19%)
		PDZ_signaling	978..1061	CDD:238492	14/95 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000