| Sequence 1: | NP_649470.2 | Gene: | eIF3a / 40563 | FlyBaseID: | FBgn0037249 | Length: | 1140 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001040552.2 | Gene: | Eif3a / 292148 | RGDID: | 1307269 | Length: | 1354 | Species: | Rattus norvegicus |
| Alignment Length: | 1270 | Identity: | 554/1270 - (43%) |
|---|---|---|---|
| Similarity: | 761/1270 - (59%) | Gaps: | 166/1270 - (13%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1 MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKR---WNYAYSETVIEPLMFKYLYLCVE 62
Fly 63 LKKSHIAKEGLFQYRNMFQLVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIAT 127
Fly 128 PESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCEALYHDIARMAFQFCLKY 192
Fly 193 NRKSEFRRLCDKLRKHLEDICKSSNQTTGVSINKVETQQLCLDTRLYLLDSAIQMELWQEAYKAI 257
Fly 258 EDIHGLMALSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKDDLQRM 322
Fly 323 AAHVLLATLSIPLPSAHPEFDRFIEADKSPLEKAQKLAVLLGLPQPPTRVSLIREVVRLNVPQLV 387
Fly 388 SEDFRNLYNWLEVDFNPLNLCKRIQSIVDFIENGPE-NALLTPYIQSLKDVTIMRLIRQISQVYE 451
Fly 452 SIKFQRLLQLASFCNIFELEKLLVESVRHNDMQIRIDHQKNSIYFGTDLTESQREYRPDGPALQS 516
Fly 517 MPSEQIRSQLVNMSTVLTRAVSIVYPNRERDQRAKLRNQMVNHYHEIKDREHQRILQRQKIIEDR 581
Fly 582 KEYIEKQNNAREEEEARRQEEESRKAKLAEQKRLEQEQEERERKRHQNEIQAIREKSLKEKVQQI 646
Fly 647 SQTAHGKKMLSKLDEEGIKKLDAEQIAKRESEELQREAKELQSKLKSQEKKIDYFERAKRLEEIP 711
Fly 712 LFEKYLAEKQVKDKEFWEATEKTRIENAIAERKDAVAQQERLKRMYPDRDEFLEALKKERASLYV 776
Fly 777 EKLKKFEAALEAERKKRLADRIIRRREERRQAFLREKEEERLRKEEEIRLAQAAEERAAAEARRL 841
Fly 842 EREAEDEKRRAQYE----KQRAKE---EEAERKIKEDRDRLSRELASERERTEKDRD---TWRPR 896
Fly 897 GGDRPSASNGGSSEWRRAAPAAS-ERNDRGGERIERGGE-RIER-GGERLER------GGERI-- 950
Fly 951 ---------ERGGDRDRKDNEGADS---SWR-------VRREPDSQRAA--------APK---DS 985
Fly 986 GAPQSR--DDK---W---------RRGGERDRDFRIDGA--------RRDRDDGPRRDRDD--GP 1026
Fly 1027 RRDRDDERGGFRRADGARRTDEPQRETGGNWRD-----APRHAD--------------------- 1065
Fly 1066 ---------RETRRPAER-----------------------RDRDVRETRGDQ--RGSAPKEAAS 1096
Fly 1097 GGVGGNWRTAPATREEKPAAKRDQAQEKENKAGDD 1131 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| eIF3a | NP_649470.2 | PAM | 429..>497 | CDD:214803 | 28/67 (42%) |
| Eif3a | NP_001040552.2 | PAM | 426..498 | CDD:214803 | 31/71 (44%) |
| ATP-synt_B | <516..603 | CDD:304375 | 35/86 (41%) | ||
| GBP_C | <566..685 | CDD:303769 | 48/118 (41%) | ||
| DUF342 | <643..737 | CDD:302792 | 46/93 (49%) | ||
| coiled coil | 650..661 | CDD:293879 | 3/10 (30%) | ||
| Interaction with EIF3B. /evidence=ECO:0000255|HAMAP-Rule:MF_03000 | 664..835 | 83/170 (49%) | |||
| coiled coil | 674..685 | CDD:293879 | 5/10 (50%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 809..844 | 14/34 (41%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 866..1249 | 118/398 (30%) | |||
| 22 X 10 AA approximate tandem repeats of [DA]-[DE]-[ED]-R-[PLIGFSV]-[RPS]-[RW]-[RL]-[GNIHT]- [DGLPTAM] | 924..1143 | 66/218 (30%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1262..1354 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C166354175 | |
| Domainoid | 1 | 1.000 | 441 | 1.000 | Domainoid score | I527 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG2072 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H2779 | |
| Inparanoid | 1 | 1.050 | 917 | 1.000 | Inparanoid score | I341 |
| OMA | 1 | 1.010 | - | - | QHG54611 | |
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0003667 | |
| OrthoInspector | 1 | 1.000 | - | - | oto98091 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_102668 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR14005 |
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 1 | 1.000 | - | - | X3031 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| 15 | 14.760 | |||||