Protein Alignment srl and si:dkey-93h22.8

DIOPT Version :9

• Sequence 1: NP_649469.2
• Gene: srl / 40562
• FlyBaseID: FBgn0037248
• Length: 1067
• Species: Drosophila melanogaster
• Sequence 2: NP_001296721.1
• Gene: si:dkey-93h22.8 / 449943
• ZFINID: ZDB-GENE-041008-203
• Length: 958
• Species: Danio rerio
• Alignment Length: 1181
• Identity: 262/1181 - (22%)
• Similarity: 425/1181 - (35%)
• Gaps: 425/1181 - (35%)

  Fly     1 MDSRMLNVFQGDTFEANYTKYESEPIFWSSNDELQLTDTLSGI----------LPIAP------- 48
            :|..:|::||..|   :....|||.....:     ||:.|..:          ||.|.
Zfish    53 LDPSILSIFQEKT---STESVESEASLLCA-----LTEILDSVDVESLSPFDTLPDAEIFAAHKS 109

  Fly    49 ---TDESLLNHNREEDLQNRKN-----------LLIYNDFLKQ--------ELSNHDANELN--- 88
               |..:||:.......|:.||           ::|.:..|:.        |:|..|.:|.|
Zfish   110 SGHTLRNLLHAPEPSSNQHPKNPQSAASKSRREVVISDRQLRPRRHSGSQIEISQRDDHEKNTKS 174

  Fly    89 --AQVYRSIADS-----GGEIAYEQQRQI--------SAIVEYDKED-IKIDGLTE-EEDIQSQS 136
              .:::|..:|:     ..|:..|..|.:        ||..|.|:|: :.::...| ||:|..||
Zfish   175 HSTRIFRIESDAVFTEDRLELLAELVRHMHPYCMKISSASTEDDEEEFVDVEAYEEPEENILDQS 239

  Fly   137 TFRTRTDSSSIGDYESHSS-DYDD------------EFDIVNEEKSPRLQVVHN-----NIGNLQ 183
            .....:.:.:...:::... ::.|            |..|::.:::..|.:.|:     |:..::
Zfish   240 ELGKESKAENASSFKAEDQHEHKDPNARNTSIKSPGEESIMSSDQNVELTIQHSALVKTNVAQIK 304

  Fly   184 SSCERKGRTLSTN-TIISEVDALGLSIDVNNFDLADF-ITKDDFAENLNACRKKESLQAQAQIKS 246
            .  ::|..|.:.| |.:.|:.|..   |.::.|.|:. ..::|.::|...|...:
Zfish   305 K--KKKTVTFALNLTSVYEIPAYN---DESDSDKAESPALEEDASKNDATCSTND---------- 354

  Fly   247 NTLADVPILLNPPVATIVA-KPGVPSSKPGDSDYDSDSIIDVETVDVL----------DMNMANI 300
                            |.| |..:.|||...:......::.::...:|          .|:....
Zfish   355 ----------------ITAFKSDITSSKNDITSPQKPKMLSLQEYRLLRLKKRPMEQRRMDYRTK 403

  Fly   301 WSI--DKPAKMGQTPDELRYVDNVKADPSWSPRSAKKTTPTIK-------ENKPEQLGNHQLAVP 356
            |..  |.|.::   ||..::  |:|  ||.:..||||    :|       :::|:.:..     |
Zfish   404 WPSLPDVPREL---PDLFKF--NLK--PSGNAHSAKK----LKAANVQTCQSEPKHVRR-----P 452

  Fly   357 ASNKPKH----KNICLVPNK---------------KQCDFLKRKVGSPSLSKLTKATTKKATESM 402
            |..:..|    .|..|||.|               .:....|.:||   ||::|:.:.:..:.:.
Zfish   453 ARTQVDHCVDPPNPVLVPLKITDEQIEDRDATQTPAEVQNSKPEVG---LSEVTQVSIEPKSSAA 514

  Fly   403 SNKQPSVK-------NTQ--CTGLGLGGKNL-SLLKQERDAALSVCAAKPIAP-------PTLST 450
            .::.|.:|       .||  |..:|:...:| |||:|....|........::|       |.||:
Zfish   515 ESELPVLKPDAVTEEQTQNSCGEIGIEASDLTSLLEQFETQACDAQTLPEVSPDESQCRLPDLSS 579

  Fly   451 TTPTLTPPAKRKLNLEEYKQRRCGGVGAVYPKPTPPKQAKIEVAAKRIAPTPVSKPTPSPKKAEI 515
            |. .|||||                        |||.|              :.:|
Zfish   580 TA-GLTPPA------------------------TPPHQ--------------IWRP--------- 596

  Fly   516 VNIVNSLKCPRTEQSSLPMDPITMAKNKVLRMLEMKRAQQLKIIDSRVSAKVPRVTKLPPLKDIV 580
                          .....|||..:.:|.::::|.:     .:..|:..:|.|..|.:.|.:..:
Zfish   597 --------------KGTKHDPIKPSSSKTIQIIEPR-----PLPPSKTHSKPPLATAINPPQAFL 642

  Fly   581 KDTYC-METEDPGTEIAPLSNKLHPDYEEIIIVSASCNTDITIPPNQLSKASPRSLLKSSVLLYN 644
            ...|| |:.:                     |.|.|||.      ..||: |||  |.:||||
Zfish   643 DHDYCGMQAQ---------------------INSPSCNY------RTLSE-SPR--LPASVLL-- 675

  Fly   645 ISNGQDANKNMSNSLIASIQSEVARQTSNTTLSTIQSNATKVMSSADKNCQHGEDMVIMHLPKDR 709
                             |..|...|..:...:.:::.......:.:..             |.||
Zfish   676 -----------------SPDSSPCRMETFEEVESLRGRGLCFSTHSPS-------------PLDR 710

  Fly   710 VRKTLVSIATQTDLQPEFPLLTLPPKRQSRERTRRNYRRRRTQGSGSNMSTSSSDFSSDCSSLVS 774
                                     .|..|.|....|:..|: .|||:.|:|||..||.
Zfish   711 -------------------------GRLKRRRYEGRYQHSRS-SSGSSCSSSSSSSSSS------ 743

  Fly   775 HRSRSQYDSIDQLRNLDVAATCGGSIGNGGYSSRSTQRHRSSVSSSSYSENGQYRRRQRRTSYNK 839
             ||||:                          |..|:|:||..|.||.|
Zfish   744 -RSRSR--------------------------SPPTKRYRSRHSGSSSS---------------- 765

  Fly   840 RRSRNQKRGSTSSSCSGSEKSDRERSRSPHRKLRHSRSRSRSKSDTRYPN-----NNSSSNNNNR 899
              ||:..|   |||.|...:..|.||||.:|    |||..||:|.:|.|.     .:......||
Zfish   766 --SRSSSR---SSSRSPVRQCGRRRSRSQNR----SRSLCRSRSGSRSPEPDCRWQSRRQKELNR 821

  Fly   900 RGFFDRNV-SQPAVEERRIVYVGRIEQETTKEILRRKFLPYGSIKQITIHYKENGMKYGFVTYER 963
            |....|.: .|.|:||||:||||.|.:......|:.:|..:|.::..|:|.:.:|..||||||..
Zfish   822 RHEEARKLRQQKAIEERRVVYVGGIRESMAPSDLKDRFSLFGKVEDCTVHLRSHGDNYGFVTYYN 886

  Fly   964 AQDAFTAIDTS---HRDSQISMYDISFGGRRAFCRSSYADLDNAGINNYNSYVFPKEAPAPNVVE 1025
            ..||:.||:..   .|..::. :||.|||||.||:|:|||||:      |..|.|  |....:..
Zfish   887 TDDAYAAIENGGKLRRPDELP-FDICFGGRRQFCKSNYADLDS------NRDVDP--ASRSRLES 942

  Fly  1026 DSFEALLLQVK 1036
            ..|:.||.|.:
Zfish   943 FDFDTLLKQAQ 953

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
srl	NP_649469.2	RRM	<906..>975	CDD:223796	27/72 (38%)
		RRM_PPARGC1A_like	914..1002	CDD:240803	38/90 (42%)
si:dkey-93h22.8	NP_001296721.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595059
Domainoid	1	1.000	62	1.000	Domainoid score	I10324
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006880
OrthoInspector	1	1.000	-	-		otm25248
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15528
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.030