Protein Alignment srl and pprc1

DIOPT Version :9

• Sequence 1: NP_649469.2
• Gene: srl / 40562
• FlyBaseID: FBgn0037248
• Length: 1067
• Species: Drosophila melanogaster
• Sequence 2: XP_001338236.3
• Gene: pprc1 / 100002463
• ZFINID: ZDB-GENE-030131-9858
• Length: 1220
• Species: Danio rerio
• Alignment Length: 1303
• Identity: 298/1303 - (22%)
• Similarity: 458/1303 - (35%)
• Gaps: 376/1303 - (28%)

  Fly     7 NVFQGDTFEANYTKYESEPIFWSSNDELQ-----LTDTLSGILPIAPTDESLLNHNRE------- 59
            |:.:.:..:.::|....|...:::.|.|:     |..::..|...:||.|...|.:.|
Zfish    22 NLDEAEMLQGSFTSNSLEFTGFNNGDALEALHGCLDPSILSIFEDSPTGEVKSNLDEESEATLLT 86

  Fly    60 ---EDLQN--RKNLLIYNDFLKQEL-SNHDANE---LNAQVYRSIADS-------GGEIAYEQQR 108
               |.|.|  .:||..::.....:| |.|...|   |.....||..:|       .|:.....||
Zfish    87 ALTEILDNVDDENLSPFDTLPDSDLFSGHKGQEHSPLRKLFTRSTPESVIHTRQFPGKSLPRMQR 151

  Fly   109 QISAIVEYDKED---------------IKIDG------LTEEEDIQSQSTFRTRTDSSSIGDYES 152
            ......|.::|:               :.:||      ::.|:|.:|...        |:|:...
Zfish   152 LSQQNSEGEEEEDGDASFSIPLSNIDLLSLDGFDWCLPVSLEQDGESMPV--------SLGELVK 208

  Fly   153 HSSDYDDEFDIVNEEKSPR--------LQVV---------------------------------- 175
            |...|.....:..||....        |:||
Zfish   209 HMHPYCMTLCVEGEEGQEHLLPERGLVLEVVDQGEHGEPILAIPDLSIPLSQADPTECEQRVPGN 273

  Fly   176 --------HNNIGNLQSS----------------CERKGRTLSTNTIISEVDALGLSIDVN---- 212
                    |:|.....:|                |:.|.|..|..|.:.|...| .|..||
Zfish   274 SIDKQEPKHDNHAQKVTSPSNVSPVEKEKEVGKVCKGKKRCKSVETPLVEQRIL-RSSKVNEEPQ 337

  Fly   213 NFDLADFITKDDFAENLNAC------------------RKKESLQAQAQIK-SNTLADVPILLNP 258
            .....:...|..|:.:|.:.                  .:::::.::|:.| :|...|...|..|
Zfish   338 KKPQKEQKKKVTFSPSLTSAEPERPKLYPPTKEPEPRDEEEQTMTSKAETKITNLTTDNNSLEKP 402

  Fly   259 PVATIVAKPGVPSSKPGDSDYDSDS-----------IIDVETVDVLDMNMANIWSIDKPAKMGQT 312
            ....:.:|...||.:|.|...:...           :...:..|.:|.      :.|...|....
Zfish   403 GEEELPSKQETPSEQPSDCQRNETKPKPLSLQQYRLLRQQKKPDPVDK------TEDYSTKWPTL 461

  Fly   313 PDELRYVDNVKADPSWSPRSAKKTT--PTIKENKPEQLGNHQLAVPASNKPKHKNICLVPNKKQC 375
            |:..:.:..:...|..|.|..:||:  |..|:..||.:.......||:  |......|||.....
Zfish   462 PEAPKELPPIPCLPDPSLRDPRKTSHIPVKKDPVPEIMPAWHPRGPAA--PPTPEALLVPPASLM 524

  Fly   376 DFLKRKVGSPSLSKLTKATTKKATESMSNKQP-------------------SVKNTQCTGLGLGG 421
            ...::.|.|.|.|   ...:.::..|...|||                   :|.....|..| |.
Zfish   525 GSSRKPVSSKSTS---SDCSSQSVHSSPQKQPAPIAVQQNTIHTETSSLERTVSQPVSTTPG-GS 585

  Fly   422 KNLSLLKQER------DAALSVCAAK-PIAPPTLST-----TT----PTLTPPAKRK-------- 462
            .:|....||.      :||.:|..:| |:.|..::|     ||    |....||||:
Zfish   586 TSLKTPSQEECLHRNPNAAHAVAPSKVPLEPQMITTHVQSSTTSAPKPCAAAPAKRETEQVVLAP 650

  Fly   463 ----------LNLEEYKQRRCGGVGAVYPKP--TPPKQAKIEVAAKRIAPTPVSKPTPSPKKAE- 514
                      .|.::...|....|..:..:|  |...||::...|:::  ...|..||.||.|.
Zfish   651 VCEQAKTTLPTNSKKLTSRSQPHVAPIAAQPFFTAQVQARVVELAEQM--RMASSETPKPKTATV 713

  Fly   515 --IVNIVNSLKCPRTEQSSL--------PMDPITMAK---------NKVLRMLEMKRAQQLKIID 560
              |.:..:.:.....:.:||        |.:...:.:         |.....:|.|..::.:..|
Zfish   714 ELIESFTSEIGIEAADLTSLLEQFEESQPKEETRVPEVCGRAAAVGNSSFEQVETKAVEKTRNHD 778

  Fly   561 -SRVSAKVPRVTKLPP---LKDIVKDTYCMET---EDPGT--------EIAPL-SNKLHPDYEEI 609
             ...:...|..|  ||   .|.|...:...:|   |.|.:        |..|| ||||....:.:
Zfish   779 LGSTAGLTPPAT--PPHQMWKPIAPVSLLGKTKKSEVPKSTTNKAIQIEARPLPSNKLRCKPQTL 841

  Fly   610 IIVSA----SCNTDITIPPNQLSKASPRSLLKSSVLLYNISNGQDANKNMSNSLIASIQSEVARQ 670
            .....    |.:.|..:||.:||:....|       .:|:       |...:.:|.:::     .
Zfish   842 TTTGQTQPFSLDHDYCLPPKELSQTEVGS-------RWNV-------KQQPSIVIKTVE-----L 887

  Fly   671 TSNTTLSTIQSNATKVMSSADKNCQHGEDMVIMHLPKDRVRKTLVSIATQT-DLQPEFP-----L 729
            .||..|   |.|.:|..||.....:..:..:.:..|.:....||.|...:| |..|..|     |
Zfish   888 PSNKPL---QKNVSKTSSSTSSVTEETQKNLSLSQPSEGTSCTLNSSVLETPDASPNRPDSESSL 949

  Fly   730 L--------------TLPPKRQSRERTRRNYRRRRTQGSGSNMSTSSSDFSSDCSSLVSHRSRSQ 780
            |              :....:|.|.|.:|.||.         .|||||:.||:.||......|.:
Zfish   950 LNEVNHKKSVDYSKCSSTKYQQDRGRQKRRYRA---------PSTSSSESSSESSSRSRSPPRKR 1005

  Fly   781 YDSIDQLRNLDVAATCGGSIGNGGYSSRSTQRHRSSVSSSSYSENGQYRRRQRRTSYNKRRSRNQ 845
            |.|...                   ||||:...||..||.|:|.     .|:||.||:..|
Zfish  1006 YRSRHS-------------------SSRSSSSSRSRSSSRSFSP-----PRRRRYSYSSSR---- 1042

  Fly   846 KRGSTSSSCSGSEKSDRERSRSPHRKLRHSRSRSRSKSDTR--YPNNNSSSNNNNRRGFFDRNVS 908
               |.|.|||.|.  .|.||...|   .|...|||...|.|  |.:..:||.:..||       .
Zfish  1043 ---SGSWSCSRSR--SRSRSTDSH---EHRHWRSRRSPDQRPGYHHVQNSSEDTKRR-------K 1092

  Fly   909 QPAVEERRIVYVGRIEQETTKEILRRKFLPYGSIKQITIHYKENGMKYGFVTYERAQDAFTAIDT 973
            :.|:||||:||||||....|:..|:.:||.:|.|::.|:|::|||..||||||...:|||.||:.
Zfish  1093 EKAIEERRVVYVGRICGNMTRMELKERFLYFGDIEECTVHFRENGDNYGFVTYYSVKDAFNAIEN 1157

  Fly   974 SH--RDSQISMYDISFGGRRAFCRSSYADLDNAGINNYNSYVFPKEAPAPNVVEDSFEALLLQVK 1036
            ..  |......:|:.|||||.||::||||||:      |....||.........| |:.||.|.:
Zfish  1158 GSILRKPNELPFDLCFGGRRQFCKASYADLDS------NREYDPKPTKGKFDALD-FDTLLKQAQ 1215

  Fly  1037 AKL 1039
            ..|
Zfish  1216 KNL 1218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
srl	NP_649469.2	RRM	<906..>975	CDD:223796	33/68 (49%)
		RRM_PPARGC1A_like	914..1002	CDD:240803	44/89 (49%)
pprc1	XP_001338236.3	RRM_SF	1098..1188	CDD:302621	44/89 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595057
Domainoid	1	1.000	62	1.000	Domainoid score	I10324
eggNOG	1	0.900	-	-		E1_28IAX
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25248
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15528
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5188
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.920