DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32944 and inaC

DIOPT Version :9

Sequence 1:	NP_788574.3	Gene:	CG32944 / 40560	FlyBaseID:	FBgn0052944	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	NP_476863.1	Gene:	inaC / 36897	FlyBaseID:	FBgn0004784	Length:	700	Species:	Drosophila melanogaster

Alignment Length:	444	Identity:	128/444 - (28%)
Similarity:	200/444 - (45%)	Gaps:	66/444 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 MQSYERCRPLLGSIWR-HRLTRISLNLLEIPLLGDDFRFLLASACQQLHELR-------ISFLGR 81
            :|..:|.:.||..:|. .|.:|            :||   :.|....|.||:       ..||.:
  Fly   266 LQPQDRDKRLLIEVWDWDRTSR------------NDF---MGSFSFSLEELQKEPVDGWYKFLSQ 315

  Fly    82 ---EHFQALIMHCFPNLWLLQVDVLPPFFLCPRQRLQLIQIIPKFHPEDHSLAMGHMLCVKCQSL 143
               ||:....:..|.::..|:.:|..     .|:..:..::..|..|  |:::...|
  Fly   316 VEGEHYNIPCVDAFNDIARLRDEVRH-----DRRPNEKRRMDNKDMP--HNMSKRDM-------- 365

  Fly   144 IPINFDHFQILRAIGKGSFGKVCIVQKRDTGILYAMKYVSRSACEMRGALGGVIKEVELLS-SLE 207
              |....|..::.|||||||||.:.::|.|..|||:|.:.:........:...:.|.::|: |..
  Fly   366 --IRAADFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGR 428

  Fly   208 HPFLVNLWFSFQDEEDLFMVCDLLTGGDLRYHLQNRVEFSEQSVALLVCELGSALEYLQANRVVH 272
            .||||::...||..:.||.|.:...||||.||:|....|.|........|:..||.:|....:::
  Fly   429 PPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHERDIIY 493

  Fly   273 RDIKPDNILLDDAGHAHLTDFNIA----TRLQKNALACSMSGTKPYMAPEVFLCALDEVAGYSYP 333
            ||:|.||||||..||..|.||.::    |..|.....|   ||..|||||:  .:.|.   ||..
  Fly   494 RDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFC---GTPNYMAPEI--VSYDP---YSIA 550

  Fly   334 VDWWSLGVVAYEMRGNIRPFVVHSNTPLAEIKNILNTPVHYPRYWSSNFVDLLQRLLSTYPGARI 398
            .||||.||:.:|......||.....|.:  .:||.:....:|:::|...:|::...|:..|..|:
  Fly   551 ADWWSFGVLLFEFMAGQAPFEGDDETTV--FRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRL 613

  Fly   399 S----TRQELHQTPMLRNIDFQRV----LEKKIKPIYKPPEDHLNCDPCLELEE 444
            .    .|||:...|..||:|:.:.    :|..|||:.|..:|..|.|.....|:
  Fly   614 GAGRYARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDDAFTKEK 667

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32944	NP_788574.3	STKc_Yank1	150..410	CDD:270730	90/268 (34%)
CG32944	NP_788574.3	S_TKc	151..405	CDD:214567	89/262 (34%)
inaC	NP_476863.1	C1_1	72..124	CDD:278556
		C1_1	137..189	CDD:278556
		C2_PKC_alpha_gamma	194..324	CDD:175992	17/72 (24%)
		S_TKc	371..629	CDD:214567	90/267 (34%)
		STKc_PKC	375..692	CDD:270722	101/303 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24356
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100