DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32944 and Stk32c

DIOPT Version :9

Sequence 1:	NP_788574.3	Gene:	CG32944 / 40560	FlyBaseID:	FBgn0052944	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	NP_001102392.1	Gene:	Stk32c / 365381	RGDID:	1305864	Length:	488	Species:	Rattus norvegicus

Alignment Length:	406	Identity:	197/406 - (48%)
Similarity:	272/406 - (66%)	Gaps:	18/406 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 INFDHFQILRAIGKGSFGKVCIVQKRDTGILYAMKYVSRSACEMRGALGGVIKEVELLSSLEHPF 210
            :|||||||||||||||||||||||||||..:|||||:::..|..|..:..|.:|:|:|..:||.|
  Rat    89 VNFDHFQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQEIEHVF 153

  Fly   211 LVNLWFSFQDEEDLFMVCDLLTGGDLRYHLQNRVEFSEQSVALLVCELGSALEYLQANRVVHRDI 275
            |||||:|||||||:|||.|||.|||||||||..|:|||.:|.|.:||:..||:||::..::|||:
  Rat   154 LVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVQFSEDTVRLYICEMALALDYLRSQHIIHRDV 218

  Fly   276 KPDNILLDDAGHAHLTDFNIATRLQKNALACSMSGTKPYMAPEVFLCALDEVAGYSYPVDWWSLG 340
            ||||||||:.||||||||||||.::....|.:::|||||||||:|...::...|||:.|||||:|
  Rat   219 KPDNILLDEQGHAHLTDFNIATIIKDGERATALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVG 283

  Fly   341 VVAYEMRGNIRPFVVHSNTPLAEIKNILNT-PVHYPRYWSSNFVDLLQRLLSTYPGARISTRQEL 404
            |:|||:....||:.:||:..:..:..:.:| .|.|...||...|.||::||:..|..|.|:.|::
  Rat   284 VMAYELLRGWRPYDIHSSNAVESLVQLFSTVSVQYVPTWSKGMVALLRKLLTVNPEHRFSSLQDM 348

  Fly   405 HQTPMLRNIDFQRVLEKKIKPIYKPPEDHLNCDPCLELEEMIVESRPLHKKKKRLAKQRS--AQR 467
            ...|.|.::.:..:.|||::|.:.|.:..|:|||..||||||:||||||||||||||.:|  :.|
  Rat   349 QTAPSLAHVLWDELSEKKVEPGFVPNKGRLHCDPTFELEEMILESRPLHKKKKRLAKNKSRDSSR 413

  Fly   468 DS---------DPETALVKEFIVYNRYKELKRKAMEQKENDWQRELELAMANSIVNSLAPIQEKP 523
            ||         |...|:.::|:::||.| |||......|     .|.....:.:.:|.|..:.:|
  Rat   414 DSSQSENDYLQDCLDAIQQDFVIFNREK-LKRSQELMSE-----PLPGPETSDMTDSTADSEAEP 472

  Fly   524 AACVVHDGDCATASSA 539
            .|..:....|.::.|:
  Rat   473 TALPMCGSICPSSGSS 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32944	NP_788574.3	STKc_Yank1	150..410	CDD:270730	143/260 (55%)
CG32944	NP_788574.3	S_TKc	151..405	CDD:214567	141/254 (56%)
Stk32c	NP_001102392.1	STKc_Yank1	93..352	CDD:270730	142/258 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347629
Domainoid	1	1.000	318	1.000	Domainoid score	I1220
eggNOG	1	0.900	-	-		E1_KOG0598
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	398	1.000	Inparanoid score	I1880
OMA	1	1.010	-	-		QHG51857
OrthoDB	1	1.010	-	-		D299857at33208
OrthoFinder	1	1.000	-	-		FOG0001907
OrthoInspector	1	1.000	-	-		otm44926
orthoMCL	1	0.900	-	-		OOG6_101414
Panther	1	1.100	-	-	O	PTHR24356
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1621
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.810