DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32944 and Dmpk

DIOPT Version :9

Sequence 1:	NP_788574.3	Gene:	CG32944 / 40560	FlyBaseID:	FBgn0052944	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	XP_038967160.1	Gene:	Dmpk / 308405	RGDID:	1309825	Length:	646	Species:	Rattus norvegicus

Alignment Length:	594	Identity:	152/594 - (25%)
Similarity:	235/594 - (39%)	Gaps:	161/594 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 LQVDVLPPFFLCPRQRLQLIQIIPKFHPEDHSLAMGHMLCVK-----CQSLIPI---------NF 148
            ||..||.|.||.....|.|:..:   |.|   |...|:...|     .|.:.||         ..
  Rat    10 LQQLVLDPGFLGLEPLLDLLLGV---HQE---LGASHLAQDKYVADFLQWVEPIAARLKEVRLQR 68

  Fly   149 DHFQILRAIGKGSFGKVCIVQKRDTGILYAMKYVSRSACEMRGALGGVIKEVELLSSLEHPFLVN 213
            |.|:||:.||:|:|.:|.:|:.:.||.:||||.:::.....||.:....:|.::|...:..::..
  Rat    69 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVKGDRRWITQ 133

  Fly   214 LWFSFQDEEDLFMVCDLLTGGDLRYHLQNRVEFSEQSVA----LLVCELGSALEYLQANRVVHRD 274
            |.|:||||..|::|.:...||||...|.   :|.|:..|    ..:.|:..|::.:.....||||
  Rat   134 LHFAFQDENYLYLVMEYYVGGDLLTLLS---KFGERIPAEMARFYLAEIVMAIDSVHRLGYVHRD 195

  Fly   275 IKPDNILLDDAGHAHLTDFNIATRLQKNALACSM--SGTKPYMAPEVFLCALDEVAG------YS 331
            |||||||||..||..|.||....:||.:....|:  .||..|::||:    |..|.|      |.
  Rat   196 IKPDNILLDRCGHIRLADFGSCLKLQPDGTVRSLVAVGTPDYLSPEI----LQAVGGGPGAGSYG 256

  Fly   332 YPVDWWSLGVVAYEMRGNIRPFVVHSNT-PLAEIKNILNTPVHYPRYWS---------SNFVDLL 386
            ...|||:|||.||||.....||...|.. ..|:|       |||..:.|         ....||:
  Rat   257 PECDWWALGVFAYEMFYGQTPFYADSTAETYAKI-------VHYREHLSLPRADMGVPEEAQDLI 314

  Fly   387 QRLLSTYPGARISTRQ----ELHQTPMLRNIDFQRVLEK--KIKPIYKPPEDHLNCD-------- 437
            :.||..   |.|...:    :..:.|....:|::.:.:.  ...|.::...|..|.|
  Rat   315 RGLLCP---AEIRLGRGGAGDFQKHPFFFGLDWEGLRDSVPPFTPDFEGATDTCNFDVVEDRLTA 376

  Fly   438 -----------------------------PCL-ELEEMIVESRPLHKKKKRL------------- 459
                                         .|: ..:..:.:..|:..:..:|
  Rat   377 MVSGGGETLSDMQEDMALGVHLPFVGYSYSCMASRDNQVTDPTPMELEALQLPVSDLQGLDLPPP 441

  Fly   460 -AKQRSAQRDSDPETALV----KEFIVYNRYKELKRKAMEQK---ENDWQRELELAMANSIVNSL 516
             :....|..::||....|    .|.:|  ..:|| ::|:|::   .....|||| |:..:..|..
  Rat   442 VSPPDQAAEEADPAAVPVPPAETETMV--TLREL-QEALEEEVLTRQSLSRELE-AIRTANQNFS 502

  Fly   517 APIQEKPAACVVHDGDCATASSAVAQLK------------GESIEFIDRTPSPQIKESAGSRLDM 569
            :.:||    ..|.:.|   ..:.|.||:            |||:..         .:..|.|::|
  Rat   503 SQLQE----AEVRNRD---LEAHVRQLQERMEMLQAPGAAGESLTH---------SQPGGRRVEM 551

  Fly   570 -----PQSP 573
                 ||||
  Rat   552 GCHGGPQSP 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32944	NP_788574.3	STKc_Yank1	150..410	CDD:270730	93/285 (33%)
CG32944	NP_788574.3	S_TKc	151..405	CDD:214567	92/279 (33%)
Dmpk	XP_038967160.1	PKc_like	69..406	CDD:419665	99/353 (28%)
Dmpk	XP_038967160.1	DMPK_coil	472..532	CDD:117396	17/68 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347625
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930