DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32944 and Stk32b

DIOPT Version :9

Sequence 1:	NP_788574.3	Gene:	CG32944 / 40560	FlyBaseID:	FBgn0052944	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	NP_001100694.1	Gene:	Stk32b / 305431	RGDID:	1306173	Length:	414	Species:	Rattus norvegicus

Alignment Length:	368	Identity:	206/368 - (55%)
Similarity:	259/368 - (70%)	Gaps:	18/368 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 INFDHFQILRAIGKGSFGKVCIVQKRDTGILYAMKYVSRSACEMRGALGGVIKEVELLSSLEHPF 210
            :|||||||||||||||||||||||||||..:|||||:::..|..|..:..|.:|::::..|||||
  Rat    18 VNFDHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCVERDEVRNVFRELQIMQGLEHPF 82

  Fly   211 LVNLWFSFQDEEDLFMVCDLLTGGDLRYHLQNRVEFSEQSVALLVCELGSALEYLQANRVVHRDI 275
            |||||:|||||||:|||.|||.|||||||||..|.|:|.:|.|.||||..||||||...::||||
  Rat    83 LVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTEGAVKLYVCELALALEYLQRYHIIHRDI 147

  Fly   276 KPDNILLDDAGHAHLTDFNIATRLQKNALACSMSGTKPYMAPEVFLCALDEVAGYSYPVDWWSLG 340
            ||||||||:.||.|:|||||||.|:....|.||:|||||||||:|...:|...||||||||||||
  Rat   148 KPDNILLDEHGHVHITDFNIATVLKGTEKASSMAGTKPYMAPEIFQVYVDGGPGYSYPVDWWSLG 212

  Fly   341 VVAYEMRGNIRPFVVHSNTPLAEIKNILNTP-VHYPRYWSSNFVDLLQRLLSTYPGARISTRQEL 404
            |.|||:....||:.:||.||:.||.|:.... |||...|....||||::||:..|..|:|:.:::
  Rat   213 VTAYELLRGWRPYEIHSATPVDEILNMFKVERVHYSSTWCEGMVDLLKKLLTKDPEIRLSSLRDI 277

  Fly   405 HQTPMLRNIDFQRVLEKKIKPIYKPPEDHLNCDPCLELEEMIVESRPLHKKKKRLAKQRS--AQR 467
            .....|.::::..|..|.:.|.:.|.:..|||||..||||||:||:|||||||||||.||  :.:
  Rat   278 QSMTYLADMNWDAVFNKALMPGFVPNKGRLNCDPTFELEEMILESKPLHKKKKRLAKHRSRDSTK 342

  Fly   468 DSDP---------ETALVKEFIVYNRYKELKRKAMEQKENDWQ 501
            ||.|         || :.||||::||.| |:|    |:.:|.|
  Rat   343 DSCPLNGHLQQCLET-VRKEFIIFNREK-LRR----QQGHDGQ 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32944	NP_788574.3	STKc_Yank1	150..410	CDD:270730	155/260 (60%)
CG32944	NP_788574.3	S_TKc	151..405	CDD:214567	154/254 (61%)
Stk32b	NP_001100694.1	STKc_Yank1	22..283	CDD:270730	155/260 (60%)
Stk32b	NP_001100694.1	S_TKc	23..272	CDD:214567	153/248 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347626
Domainoid	1	1.000	318	1.000	Domainoid score	I1220
eggNOG	1	0.900	-	-		E1_KOG0598
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H48654
Inparanoid	1	1.050	398	1.000	Inparanoid score	I1880
OMA	1	1.010	-	-		QHG51857
OrthoDB	1	1.010	-	-		D299857at33208
OrthoFinder	1	1.000	-	-		FOG0001907
OrthoInspector	1	1.000	-	-		otm44926
orthoMCL	1	0.900	-	-		OOG6_101414
Panther	1	1.100	-	-	O	PTHR24356
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1621
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810