DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32944 and Sgk2

DIOPT Version :9

Sequence 1:	NP_788574.3	Gene:	CG32944 / 40560	FlyBaseID:	FBgn0052944	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	NP_038759.1	Gene:	Sgk2 / 27219	MGIID:	1351318	Length:	367	Species:	Mus musculus

Alignment Length:	316	Identity:	104/316 - (32%)
Similarity:	160/316 - (50%)	Gaps:	45/316 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 PINFDHFQILRAIGKGSFGKVCIVQKRDTGILYAMKYVSRSACEMRGALGGVIKEVE-------- 201
            |.:||   .|:.||||::|||.:.:::..|..||:|.:.:.:         ::|..|
Mouse    32 PTDFD---FLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKS---------ILKNKEQNHIMAER 84

  Fly   202 --LLSSLEHPFLVNLWFSFQDEEDLFMVCDLLTGGDLRYHLQNRVEFSEQSVALLVCELGSALEY 264
              ||.::.|||||.|.:|||..|.|:.|.|.:.||:|.:|||....|.|........|:.||:.|
Mouse    85 NVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYTAEVASAIGY 149

  Fly   265 LQANRVVHRDIKPDNILLDDAGHAHLTDFNIATR-LQKNALACSMSGTKPYMAPEVFLCALDEVA 328
            |.:..:::||:||:|||||..||..||||.:... ::......:..||..|:||||.     ...
Mouse   150 LHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKECVEPEETTSTFCGTPEYLAPEVL-----RKE 209

  Fly   329 GYSYPVDWWSLGVVAYEMRGNIRPFVVHSNTPLAEI-KNILNTPVHYPRYWSSNFVDLLQRLLST 392
            .|...||||.||.|.|||...:.||.   ||.:|:: :|||:.|:..|...:....||||.||..
Mouse   210 PYDRAVDWWCLGAVLYEMLHGLPPFF---NTDVAQMYENILHQPLQIPGGRTVAACDLLQGLLHK 271

  Fly   393 YPGARISTRQELHQTPMLRN------IDFQRVLEKKIKPIYKP----PEDHLNCDP 438
            ....|:.::::...   ::|      |::..:..|::.|.:.|    |.|..:.||
Mouse   272 DQRQRLGSKEDFLD---IKNHMFFSPINWDDLYHKRLTPPFNPNVEGPADLKHFDP 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32944	NP_788574.3	STKc_Yank1	150..410	CDD:270730	92/271 (34%)
CG32944	NP_788574.3	S_TKc	151..405	CDD:214567	92/265 (35%)
Sgk2	NP_038759.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28
		PKc_like	39..359	CDD:389743	100/306 (33%)
		Nuclear localization signal. /evidence=ECO:0000250	68..78		2/18 (11%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0598
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900