DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32944 and LATS2

DIOPT Version :9

Sequence 1:NP_788574.3 Gene:CG32944 / 40560 FlyBaseID:FBgn0052944 Length:576 Species:Drosophila melanogaster
Sequence 2:NP_055387.2 Gene:LATS2 / 26524 HGNCID:6515 Length:1088 Species:Homo sapiens


Alignment Length:350 Identity:106/350 - (30%)
Similarity:154/350 - (44%) Gaps:75/350 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   151 FQILRAIGKGSFGKVCIVQKRDTGILYAMKYVSRSACEMRGALGGVIKEVELLSSLEHPFLVNLW 215
            |..::.:|.|:||:||:..|.||..|||||.:.:.....|..:..|..|.::|:..::.::|.|:
Human   668 FVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVKLY 732

  Fly   216 FSFQDEEDLFMVCDLLTGGDLRYHLQNRVEFSEQSVALLVCELGSALEYLQANRVVHRDIKPDNI 280
            :||||::.|:.|.|.:.|||:...|.....|.|......:.||..|:|.:.....:|||||||||
Human   733 YSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNI 797

  Fly   281 LLDDAGHAHLTDFNIAT--------------------------------------RLQ------- 300
            |:|..||..||||.:.|                                      ||:       
Human   798 LIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRAR 862

  Fly   301 ---KNALACSMSGTKPYMAPEVFLCALDEVAGYSYPVDWWSLGVVAYEMRGNIRPFVVHSNTPLA 362
               :..||.|:.||..|:||||.|     ..||:...||||:||:.:||.....||:  :.||..
Human   863 KQHQRCLAHSLVGTPNYIAPEVLL-----RKGYTQLCDWWSVGVILFEMLVGQPPFL--APTPTE 920

  Fly   363 EIKNILN--TPVHYPRY--WSSNFVDLLQRLLSTYP------GARISTRQELHQTPMLRNIDFQR 417
            ....::|  ..:|.|..  .|....||:.:|..:..      ||     .:|...|....|||..
Human   921 TQLKVINWENTLHIPAQVKLSPEARDLITKLCCSADHRLGRNGA-----DDLKAHPFFSAIDFSS 980

  Fly   418 VLEKKIKPIYKP----PEDHLNCDP 438
            .:.|:..| |.|    |.|..|.||
Human   981 DIRKQPAP-YVPTISHPMDTSNFDP 1004

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32944NP_788574.3 STKc_Yank1 150..410 CDD:270730 94/316 (30%)
S_TKc 151..405 CDD:214567 92/311 (30%)
LATS2NP_055387.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 24..49
UBA_LATS2 101..141 CDD:270581
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 271..323
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 383..428
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 454..483
PPxY motif 515..518
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 543..592
STKc_LATS2 666..1046 CDD:173715 105/349 (30%)
S_TKc 668..973 CDD:214567 94/316 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 994..1022 4/10 (40%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1056..1088
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165154027
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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