Protein Alignment CG32944 and MAST2

DIOPT Version :9

• Sequence 1: NP_788574.3
• Gene: CG32944 / 40560
• FlyBaseID: FBgn0052944
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: XP_011539361.1
• Gene: MAST2 / 23139
• HGNCID: 19035
• Length: 1870
• Species: Homo sapiens
• Alignment Length: 471
• Identity: 117/471 - (24%)
• Similarity: 202/471 - (42%)
• Gaps: 86/471 - (18%)

  Fly   149 DHFQILRAIGKGSFGKVCIVQKRDTGILYAMKYVSRSACEMRGALGGVIKEVELLSSLEHPFLVN 213
            :.|:.::.|..|::|.|.:|:.:.|...:|||.:::....:|..:.....|.::|:..|:||:|:
Human   582 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVS 646

  Fly   214 LWFSFQDEEDLFMVCDLLTGGDLRYHLQNRVEFSEQSVALLVCELGSALEYLQANRVVHRDIKPD 278
            ::.||..:..|.||.:.:.|||....|:|........|.|...|...|||||....:||||:|||
Human   647 MFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNYGIVHRDLKPD 711

  Fly   279 NILLDDAGHAHLTDFNIAT-------------RLQKNA---LACSMSGTKPYMAPEVFLCALDEV 327
            |:|:...||..||||.::.             .::|:|   |...:.||..|:||||.|     .
Human   712 NLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVIL-----R 771

  Fly   328 AGYSYPVDWWSLGVVAYEMRGNIRPFVVHSNTPLAEIKNILNTPVHYP---RYWSSNFVDLLQRL 389
            .||..|||||::|::.||......||  ..:||......:::..:.:|   .....:..||..:|
Human   772 QGYGKPVDWWAMGIILYEFLVGCVPF--FGDTPEELFGQVISDEIVWPEGDEALPPDAQDLTSKL 834

  Fly   390 LSTYPGARIST--RQELHQTPMLRNIDFQRVLEKKIKPIYK----------------------PP 430
            |...|..|:.|  ..|:.|.|....:|:..:|.:|.:.|.:                      ..
Human   835 LHQNPLERLGTGSAYEVKQHPFFTGLDWTGLLRQKAEFIPQLESEDDTSYFDTRSERYHHMDSED 899

  Fly   431 EDHLNCDPCLELEEMIVES---RPLHKKKKRLAKQRSAQRDSDPETALVKEFIVYNRYKELKRKA 492
            |:.::.|.|||:.:....|   ..::...:||:...  :|.:.|.|               ||..
Human   900 EEEVSEDGCLEIRQFSSCSPRFNKVYSSMERLSLLE--ERRTPPPT---------------KRSL 947

  Fly   493 MEQKENDWQRELELAMANSIVNSLAPIQEKPAACVVHDGDCATASSAVAQLKGESIEFIDRTPSP 557
            .|:||:.             .:.||.::.:..:.|:...:......:|::   .|....|.:|..
Human   948 SEEKEDH-------------SDGLAGLKGRDRSWVIGSPEILRKRLSVSE---SSHTESDSSPPM 996

  Fly   558 QIKESAGSRLDMPQSP 573
            .::......||.|:.|
Human   997 TVRRRCSGLLDAPRFP 1012

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32944	NP_788574.3	STKc_Yank1	150..410	CDD:270730	86/280 (31%)
		S_TKc	151..405	CDD:214567	84/274 (31%)
MAST2	XP_011539361.1	DUF1908	266..547	CDD:286070
		STKc_MAST	583..862	CDD:270760	86/285 (30%)
		S_TKc	584..857	CDD:214567	86/279 (31%)
		PDZ_signaling	1177..1258	CDD:238492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154016
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930