DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32944 and Sgk3

DIOPT Version :9

Sequence 1:	NP_788574.3	Gene:	CG32944 / 40560	FlyBaseID:	FBgn0052944	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	NP_001032848.1	Gene:	Sgk3 / 170755	MGIID:	2182368	Length:	496	Species:	Mus musculus

Alignment Length:	444	Identity:	137/444 - (30%)
Similarity:	203/444 - (45%)	Gaps:	79/444 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 LEIP---LLGDDF--RFLLASACQQLHELRISFLGREHFQALIMHCFPNLW-------LLQVDVL 103
            |:||   :.||:|  .|:         :.|.:.| .|..|.|:.  :|.|:       .||:|
Mouse    70 LKIPAKRIFGDNFDPDFI---------KQRRAGL-NEFIQNLVR--YPELYNHPDVRAFLQMD-- 120

  Fly   104 PPFFLCPRQRLQLIQIIPKFHPEDHSLAMGHMLCVKCQSLIPINFDH-----FQILRAIGKGSFG 163
                 .||.     |..|....::.|.:..|... :..:|.|....|     |..|:.|||||||
Mouse   121 -----SPRH-----QSDPSEDEDERSTSKPHSTS-RNINLGPTGNPHAKPTDFDFLKVIGKGSFG 174

  Fly   164 KVCIVQKRDTGILYAMKYVSRSACEMRGALGGVIKEVE-LLSSLEHPFLVNLWFSFQDEEDLFMV 227
            ||.:.:::..|..||:|.:.:.....|.....::.|.. ||.:::|||||.|.:|||..|.|:.|
Mouse   175 KVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFV 239

  Fly   228 CDLLTGGDLRYHLQNRVEFSEQSVALLVCELGSALEYLQANRVVHRDIKPDNILLDDAGHAHLTD 292
            .|.:.||:|.:|||....|.|........|:.|||.||.:.::|:||:||:|||||..||..|||
Mouse   240 LDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTD 304

  Fly   293 FNIATRLQKNALACS-----MSGTKPYMAPEVFLCALDEVAGYSYPVDWWSLGVVAYEMRGNIRP 352
            |.:.    |..:|.|     ..||..|:||||.     ....|...||||.||.|.|||...:.|
Mouse   305 FGLC----KEGIAISDTTTTFCGTPEYLAPEVI-----RKQPYDNTVDWWCLGAVLYEMLYGLPP 360

  Fly   353 FVVHSNTPLAEI-KNILNTPVHYPRYWSSNFVDLLQRLLSTYPGARISTRQ---ELHQTPMLRNI 413
            |....   :||: .|||:.|::.....|.....:|:.||......|:..::   |:...|...::
Mouse   361 FYCRD---VAEMYDNILHKPLNLRPGVSLTAWSILEELLEKNRQNRLGAKEDFLEIQNHPFFESL 422

  Fly   414 DFQRVLEKKIKPIYKP----PEDHLNCDP-----------CLELEEMIVESRPL 452
            .:..:::|||.|.:.|    |:|..|.|.           |:..:..||.:..|
Mouse   423 SWTDLVQKKIPPPFNPNVAGPDDIRNFDAVFTEETVPYSVCVSSDYSIVNASVL 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32944	NP_788574.3	STKc_Yank1	150..410	CDD:270730	99/274 (36%)
CG32944	NP_788574.3	S_TKc	151..405	CDD:214567	97/263 (37%)
Sgk3	NP_001032848.1	PX_CISK	12..120	CDD:132780	16/61 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	121..157		8/41 (20%)
		S_TKc	162..419	CDD:214567	98/268 (37%)
		STKc_SGK3	165..490	CDD:270755	110/324 (34%)
		Nuclear localization signal. /evidence=ECO:0000250	195..205		1/9 (11%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0598
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900