DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32944 and mast3a

DIOPT Version :9

Sequence 1:	NP_788574.3	Gene:	CG32944 / 40560	FlyBaseID:	FBgn0052944	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	XP_021326924.1	Gene:	mast3a / 100534685	ZFINID:	ZDB-GENE-040914-35	Length:	1355	Species:	Danio rerio

Alignment Length:	477	Identity:	126/477 - (26%)
Similarity:	200/477 - (41%)	Gaps:	85/477 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 PINFDHFQILRAIGKGSFGKVCIVQKRDTGILYAMKYVSRSACEMRGALGGVIKEVELLSSLEHP 209
            |:..| |:.::.|..|::|.|.:|:.|:|...:|||.::|....:|..:..|..|.::|:..|:|
Zfish   361 PLERD-FETIKLISNGAYGAVYLVRHRETRQRFAMKKINRQNLILRNQIQQVFVERDILTFAENP 424

  Fly   210 FLVNLWFSFQDEEDLFMVCDLLTGGDLRYHLQNRVEFSEQSVALLVCELGSALEYLQANRVVHRD 274
            |:|:::.||:....|.||.:.:.|||....|:|..........:...|...|||||....:||||
Zfish   425 FVVSMYCSFETRRHLCMVMEYVEGGDCANLLKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRD 489

  Fly   275 IKPDNILLDDAGHAHLTDF--------NIATRL--------QKNALACSMSGTKPYMAPEVFLCA 323
            :||||:|:...||..||||        |:.|.|        .:..:...:.||..|:||||.|
Zfish   490 LKPDNLLITSMGHIKLTDFGLSKIGLMNMTTNLYEEHMEKDTREFIDKQLCGTPEYIAPEVIL-- 552

  Fly   324 LDEVAGYSYPVDWWSLGVVAYEMRGNIRPFVVHSNTPLAEIKNILNTPVHYP---RYWSSNFVDL 385
               ..||..|||||::|::.||......||  ..:||......:::..:.:|   ....:...||
Zfish   553 ---RQGYGKPVDWWAMGIILYEFLVGCVPF--FGDTPEELFGQVVSDEIEWPVGDDALPAESQDL 612

  Fly   386 LQRLLSTYPGARIST--RQELHQTPMLRNIDFQRVLEKKIKPIYKPPEDHLNCDPCLELEE--MI 446
            :.:||...|..|:.|  ..|:........:|:..:|.:|.:.|           |.||.|:  ..
Zfish   613 ITKLLRQSPLERLGTGGAAEVKHHIFFHGLDWSGLLRQKAEFI-----------PQLETEDDTSY 666

  Fly   447 VESRPLHKKKKRLAKQRSAQRDSDPETALVKEF-------------IVYNRYKEL---------- 488
            .::|          ..|....|.|.||...:.:             .||:..::|
Zfish   667 FDTR----------SDRYHHSDEDDETNDDESYQDIKFSSCSHRFSKVYSSSEQLASPSNLSLSS 721

  Fly   489 -KRKAMEQKENDWQRELELAMANSIVNSLAPIQEKPAACVVHDGDCATASSAVAQLKGESIEFID 552
             :|...|:||:.|.....|:...:      |.|.:||.   ...|.:..|.::......|....:
Zfish   722 SERSCSEEKEDRWDTHSALSPVET------PRQIQPAD---RKQDTSRGSPSLRPRASSSSSQPE 777

  Fly   553 RTPSPQIKESAGSRLDMPQSPF 574
            |..||.|..|..|...||...|
Zfish   778 RGTSPLILNSTQSLEAMPHFAF 799

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32944	NP_788574.3	STKc_Yank1	150..410	CDD:270730	85/280 (30%)
CG32944	NP_788574.3	S_TKc	151..405	CDD:214567	85/274 (31%)
mast3a	XP_021326924.1	DUF1908	57..328	CDD:312475
		STKc_MAST	365..644	CDD:270760	86/286 (30%)
		PDZ	912..993	CDD:214570
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589155
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930