DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32944 and mast3

DIOPT Version :9

Sequence 1:	NP_788574.3	Gene:	CG32944 / 40560	FlyBaseID:	FBgn0052944	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	XP_031761059.1	Gene:	mast3 / 100494808	XenbaseID:	XB-GENE-5928376	Length:	1492	Species:	Xenopus tropicalis

Alignment Length:	478	Identity:	124/478 - (25%)
Similarity:	205/478 - (42%)	Gaps:	85/478 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 CQSLIPINFDHFQILRAIGKGSFGKVCIVQKRDTGILYAMKYVSRSACEMRGALGGVIKEVELLS 204
            |:|       .|:.::.|..|::|.|.:|:.::....:|||.:::....:|..:..|..|.::|:
Frog   403 CES-------DFETIKLISNGAYGAVYLVRHKEMRQRFAMKKINKQNLILRNQIQQVFVERDILT 460

  Fly   205 SLEHPFLVNLWFSFQDEEDLFMVCDLLTGGDLRYHLQNRVEFSEQSVALLVCELGSALEYLQANR 269
            ..|:||:|:::.||:....|.||.:.:.|||....|:|..........:...|...|||||....
Frog   461 FAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMSRMYFAETVLALEYLHNYG 525

  Fly   270 VVHRDIKPDNILLDDAGHAHLTDF--------NIATRL--------QKNALACSMSGTKPYMAPE 318
            :||||:||||:|:...||..||||        |:.|.|        .:..|...:.||..|:|||
Frog   526 IVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMNMTTNLYEGHIEKDTREFLDKQVCGTPEYIAPE 590

  Fly   319 VFLCALDEVAGYSYPVDWWSLGVVAYEMRGNIRPFVVHSNTPLAEIKNILNTPVHYP---RYWSS 380
            |.|     ..||..|||||::|::.||......||  ..:||......:::..:.:|   ....:
Frog   591 VIL-----RQGYGKPVDWWAMGIILYEFLVGCVPF--FGDTPEELFGQVISDEIIWPGGEEALPT 648

  Fly   381 NFVDLLQRLLSTYPGARIST--RQELHQTPMLRNIDFQRVLEKKIKPIYKPPEDHLNCDPCLELE 443
            :..||:.|||...|..|:.|  .||:.|......:|:..:|.:|.:.:           |.||.|
Frog   649 DAQDLITRLLRQNPLERLGTGGAQEVKQHTFFLPLDWNGLLRQKAEFV-----------PQLEAE 702

  Fly   444 EMIVESRPLHKKKKRLAKQRSAQRDSDPETALVKEFI--------VYNRYKEL-----------K 489
            :.........::...||.:...:.:.|..:..:::|.        ||:..:.|           :
Frog   703 DDTSYFDTRSERYHHLASEEDEETNDDESSVEIRQFSSCSHRFSKVYSSSEHLATQLNLSFSSTE 767

  Fly   490 RKAMEQKE---NDWQRELELAMANSIVNSLAPIQEKPAACVVHDGDCATASSAVAQLKGESIEFI 551
            |...::||   :.|:|.|.:....   |.|.|  |.........|     ||..:.|.
Frog   768 RSHSDEKEEHSDRWERTLSIEEEK---NRLGP--ENRLRSWTSSG-----SSHHSWLS------- 815

  Fly   552 DRTPSPQIKESAGSRLDMPQSPF 574
            :|:.||.:..|..|...||:..|
Frog   816 ERSASPNVLTSTCSLDTMPKFAF 838

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32944	NP_788574.3	STKc_Yank1	150..410	CDD:270730	86/280 (31%)
CG32944	NP_788574.3	S_TKc	151..405	CDD:214567	85/274 (31%)
mast3	XP_031761059.1	DUF1908	88..368	CDD:401031
		STKc_MAST	406..685	CDD:270760	86/285 (30%)
		PDZ	980..1061	CDD:214570
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000