Protein Alignment lost and Mthfs

DIOPT Version :9

• Sequence 1: NP_649466.1
• Gene: lost / 40559
• FlyBaseID: FBgn0263594
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001097432.1
• Gene: Mthfs / 37699
• FlyBaseID: FBgn0085453
• Length: 201
• Species: Drosophila melanogaster
• Alignment Length: 160
• Identity: 38/160 - (23%)
• Similarity: 72/160 - (45%)
• Gaps: 22/160 - (13%)

  Fly    34 KRSLRVQTWKKIQEGKVGIGFNNIFNRIPSFVGADKAAALFANEEEFKKAQHIKVNIDRVLHEFK 98
            :.:|:|...|::::...||....|..:      :....|.....|.|::||.:.:.:. ...|..
  Fly     6 QNTLKVALRKRMKDALKGIDAEAIARQ------SQAVTAKVLQSEIFRQAQRVSIYLS-TASELD 63

  Fly    99 ELALLA-----DKSVYLPSTRESSALCLKVDVLADATEEQK-----KEALRVQDIQKFRSEIGLD 153
            ..|||:     :|.|::| |.|.|.:.:   |.....||.:     |..::..|.::.| |..:.
  Fly    64 TTALLSEMFRLEKMVFVP-TYEGSRMKM---VRLRGMEEYESLPLTKWNIKQPDFKEAR-EDAMT 123

  Fly   154 SGLKLDIVVIGSVVVSREGYRIGRGNGFAD 183
            :|..:|:.::..|..:|.|.|:|.|.|:.|
  Fly   124 NGHGIDLFIVPGVAFTRCGARMGHGMGYYD 153

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lost	NP_649466.1	5-FTHF_cyc-lig	67..238	CDD:294257	32/127 (25%)
		RRM_MTHFSD	384..455	CDD:240716
Mthfs	NP_001097432.1	5-FTHF_cyc-lig	10..201	CDD:294257	37/156 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0212
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900