Protein Alignment lost and lost

DIOPT Version :10

• Sequence 1: NP_649466.1
• Gene: lost / 40559
• FlyBaseID: FBgn0263594
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: XP_061497720.1
• Gene: lost / 1271684
• VectorBaseID: AGAMI1_012946
• Length: 775
• Species: Anopheles gambiae
• Alignment Length: 608
• Identity: 190/608 - (31%)
• Similarity: 278/608 - (45%)
• Gaps: 129/608 - (21%)

  Fly     2 ED--QSNAAPAVAAENGGNTAQEVSSTTQPIEPTKRSLRVQTWKKIQ----EGKVGIGFNNIFNR 60
            ||  |.|:.|.:  ||..:.|           |:||..|.|.|..::    :|.....:.|  .:
Mosquito     7 EDDVQKNSPPPM--ENNDDNA-----------PSKRFYRQQVWTTMKALFPQGSASSNYVN--RK 56

  Fly    61 IPSFVGADKAAALFANEEEFKKAQHIKVNIDRVLHEFKELALLADKSVYLPSTRESSALCLKVDV 125
            ||.|..|::.|...|...|||:|.:||||||......|...|.|:|::::..:::|..|..|:.
Mosquito    57 IPLFPAAEQTAERLAETPEFKQATNIKVNIDMAQEAVKLQVLKANKTLFVAPSQKSDYLYAKIK- 120

  Fly   126 LADATEE----QKKEALRVQDIQKFRSEIGLDSGLKLDIVVIGSVVVSREGYRIGRGNGFADLDI 186
            |..:.||    |::..:::...:....|:|:|....||:||:|.|.||..|.|||:|||:.||:|
Mosquito   121 LPSSVEEVPLVQQRRIVKMLAGEDTYEELGIDQTEPLDMVVVGCVAVSERGQRIGKGNGYVDLEI 185

  Fly   187 GLLIELGAITPKTIIVTIVHDMQVVDSLPPNLFQKYDTPVDIIATPTEIIRVPKRLSFPN----G 247
            .:|::||.|||||:|.|.|.|.||...|..:|||.||..||:|.|||.:|||..|   |.    |
Mosquito   186 AILVQLGVITPKTVIATTVADEQVFSELQADLFQPYDFTVDLIVTPTRVIRVEPR---PEPRAIG 247

  Fly   248 VYWELLSERRLKILPVLQQLKEREEKAGKSISLKEEDTDVEQ--------------HQNNRRRRG 298
            |.|.|||.|||.::.||::||||.|..||.|.||:||||||.              .|.:|||:.
Mosquito   248 VQWGLLSSRRLDVVRVLKKLKERLESEGKHIELKDEDTDVESFRKRRTRGSGSAGGQQQDRRRQS 312

  Fly   299 PVRRRIQRGNPGRTTSQTDNEQPQG------ETAQKRTP--RRKGRFVNRRRRTTKSEGDQSGVE 355
            ..|||..|.:......::.|||..|      |:.:...|  |||.|:..:.||.::.:....|..
Mosquito   313 NRRRRSTRNSAAGEGGKSGNEQDGGNGDGGNESGEGGGPRMRRKRRYSRKPRRYSRRDSGDYGSP 377

  Fly   356 AGAKT----------DDRKLPEAGTDERRSKKNKNSDFC-------------------------- 384
            .|.:|          ..|:.|..|....|.:.|..:...
Mosquito   378 DGGRTGGEEGGDGQQHQRQRPHPGGKGGRLRPNNKAGAANGTNGQPAAQQKQQRPPRQPKPQLQD 442

  Fly   385 ---IKLTNLSRDIRVKDLKSELRKRECTPMSISWKGHFGKCFLHFGNRKGVPSTQDDMDKVLKSL 446
               |:::|:. .:..||.|.|||.|:|.|..|| :...|:|.|.|..|..: ..|...|::|:.|
Mosquito   443 SVRIRVSNMF-SVPFKDFKDELRTRDCYPAKIS-QSRNGRCLLIFPKRDDL-EEQAQADELLQKL 504

  Fly   447 NDLSLTITTGGETAPAAAAGEGGEKAESAETATPVQTKTILVNVEL----IQFGEKKSAS-STGA 506
            .|:.:::.......|                      |.|.:..||    ..|||..:.| ::.|
Mosquito   505 ADMRISVPQKNSAEP----------------------KQIKLKCELQPKSKDFGENDATSIASAA 547

  Fly   507 NAGAGEDGKADAQNGGEAVTVAG 529
            |..|.:     |.:.|:.:.|||
Mosquito   548 NRAARK-----ANDAGQKLGVAG 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lost	NP_649466.1	5-FTHF_cyc-lig	34..232	CDD:444864	78/205 (38%)
		RRM_SF	384..455	CDD:473069	23/99 (23%)
lost	XP_061497720.1	None