DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14647 and KCTD5

DIOPT Version :9

Sequence 1:	NP_649465.6	Gene:	CG14647 / 40558	FlyBaseID:	FBgn0037244	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_061865.1	Gene:	KCTD5 / 54442	HGNCID:	21423	Length:	234	Species:	Homo sapiens

Alignment Length:	114	Identity:	48/114 - (42%)
Similarity:	77/114 - (67%)	Gaps:	2/114 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 NRWVKLNVGGQIYATTIDTLVGREPDSMLARMFLQNGSMKPSERDEQGAYLIDRSPRYFEPIINY 97
            ::||:|||||..:.||..||. |:|.|.|.|:...:..: .|::||.|||||||.|.||.|::||
Human    43 SKWVRLNVGGTYFLTTRQTLC-RDPKSFLYRLCQADPDL-DSDKDETGAYLIDRDPTYFGPVLNY 105

  Fly    98 LRHGQFVCDSNISVLGVLEEARFFGIFSLVTHLEERLGQQETPLGDRPL 146
            ||||:.|.:.:::..||||||.|:.|.||:..:::::.::::.....|:
Human   106 LRHGKLVINKDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKTSQVPV 154

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14647	NP_649465.6	BTB	35..138	CDD:197585	47/102 (46%)
		BTB	36..126	CDD:295341	44/89 (49%)
		Pentapeptide_4	160..241	CDD:290330
		Pentapeptide	166..202	CDD:279183
		Pentapeptide	204..243	CDD:279183
		Pentapeptide_4	248..321	CDD:290330
		Pentapeptide	249..287	CDD:279183
		Pentapeptide	284..322	CDD:279183
KCTD5	NP_061865.1	BTB_POZ_KCTD5	40..151	CDD:349698	47/109 (43%)
KCTD5	NP_061865.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	213..234
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D545341at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920