DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14647 and inso-1

DIOPT Version :9

Sequence 1:	NP_649465.6	Gene:	CG14647 / 40558	FlyBaseID:	FBgn0037244	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_508239.2	Gene:	inso-1 / 180473	WormBaseID:	WBGene00016871	Length:	271	Species:	Caenorhabditis elegans

Alignment Length:	224	Identity:	71/224 - (31%)
Similarity:	109/224 - (48%)	Gaps:	53/224 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 DDAAPAAGDFVAA---SGF----APNRWVKLNVGGQIYATTIDTLVGREPDSMLARMFLQNGSMK 72
            ||:....|  |||   :||    :.:.||:|||||:::.||..||: |||.|.|.|: .|:....
Worm    58 DDSTNQNG--VAAVKTNGFHYGSSSSSWVRLNVGGKVFQTTRSTLM-REPCSFLYRL-CQDEMGL 118

  Fly    73 PSERDEQGAYLIDRSPRYFEPIINYLRHGQFVCDSNISVLGVLEEARFFGIFSLVTHLEERLGQQ 137
            |::|||.|||||||.|.:|.||:||||||:.:.:..:|..|:|.||.|:.:.||...:.:|:..:
Worm   119 PTDRDETGAYLIDRDPDFFSPILNYLRHGKLIMNPGLSEEGILAEADFYNLPSLSQLIMDRIQDR 183

  Fly   138 ETPLGDRPLTRNDVIKAIIQ------TSVITELRFQGVNLSGADLRKLDFRNINFKYANMSHCNL 196
            |..:.|   ..|..:..::|      .||::.:                  ...:|...:...|.
Worm   184 ENSVKD---ATNKFVYRVLQCHEEELASVVSAM------------------TDGWKIVQVVPINS 227

  Fly   197 SHTNLN-------YCCLERADLQYANLEC 218
            ::||..       .|.:||        ||
Worm   228 NYTNYTTEQPQEYLCIVER--------EC 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14647	NP_649465.6	BTB	35..138	CDD:197585	48/102 (47%)
		BTB	36..126	CDD:295341	44/89 (49%)
		Pentapeptide_4	160..241	CDD:290330	10/66 (15%)
		Pentapeptide	166..202	CDD:279183	4/35 (11%)
		Pentapeptide	204..243	CDD:279183	5/15 (33%)
		Pentapeptide_4	248..321	CDD:290330
		Pentapeptide	249..287	CDD:279183
		Pentapeptide	284..322	CDD:279183
inso-1	NP_508239.2	BTB_POZ_KCTD2-like	83..167	CDD:349671	44/85 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D545341at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920