DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14647 and F22E5.8

DIOPT Version :9

Sequence 1:	NP_649465.6	Gene:	CG14647 / 40558	FlyBaseID:	FBgn0037244	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_001364741.1	Gene:	F22E5.8 / 173610	WormBaseID:	WBGene00017707	Length:	232	Species:	Caenorhabditis elegans

Alignment Length:	143	Identity:	41/143 - (28%)
Similarity:	72/143 - (50%)	Gaps:	11/143 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 VKLNVGGQIYATTIDTLVGREPDSMLARMFLQNGSMKPSERDEQGAYLIDRSPRYFEPIINYLRH 100
            |:|:|||.|:.|:..||.  :.:..|..|...:..:|   .||.|:..|||||::|:.|:|::|.
Worm     5 VQLDVGGTIFKTSKSTLT--KFNGFLKIMLESDIGLK---IDESGSIFIDRSPKHFDLILNFMRD 64

  Fly   101 GQFVCDS-NISVLGVLEEARFFGIFSLVTHLEERLGQQETPLGDRPLTRND-----VIKAIIQTS 159
            |..|..| .::|..:|.||:|:.:..|:.....::...:.|........||     ::.|..:..
Worm    65 GDVVLPSCELTVKELLAEAQFYLLDELIELCSLKIEPVQAPKIKLRFIENDSQLLQILAAQQKPM 129

  Fly   160 VITELRFQGVNLS 172
            :|.|....|.::|
Worm   130 LIIEYCMVGNDMS 142

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14647	NP_649465.6	BTB	35..138	CDD:197585	33/102 (32%)
		BTB	36..126	CDD:295341	32/90 (36%)
		Pentapeptide_4	160..241	CDD:290330	4/13 (31%)
		Pentapeptide	166..202	CDD:279183	2/7 (29%)
		Pentapeptide	204..243	CDD:279183
		Pentapeptide_4	248..321	CDD:290330
		Pentapeptide	249..287	CDD:279183
		Pentapeptide	284..322	CDD:279183
F22E5.8	NP_001364741.1	BTB_2	5..95	CDD:396684	33/94 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I4071
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960