DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14647 and kctd17

DIOPT Version :9

Sequence 1:	NP_649465.6	Gene:	CG14647 / 40558	FlyBaseID:	FBgn0037244	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	XP_004913948.1	Gene:	kctd17 / 101733823	XenbaseID:	XB-GENE-6035411	Length:	233	Species:	Xenopus tropicalis

Alignment Length:	235	Identity:	74/235 - (31%)
Similarity:	112/235 - (47%)	Gaps:	39/235 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 PAAGDFVAASG----FAPNRWVKLNVGGQIYATTIDTLVGREPDSMLARMFLQNGSMKPSERDEQ 79
            |..|::.||..    ....:||:|||||:::.||..||. |||:|.|.|:..:  |...||:||.
Frog     4 PRDGEYGAAYSNWCVVKEGQWVRLNVGGKVFLTTKQTLC-REPNSFLCRLCQE--SQLLSEKDES 65

  Fly    80 GAYLIDRSPRYFEPIINYLRHGQFVCDSNISVLGVLEEARFFGIFSLVTHLEERLGQQETPLGDR 144
            ||:||||.|.||..|:.|||||:.:.|.|:|:.||||||.|:.|.||:..:.|::...:
Frog    66 GAFLIDRDPSYFGAILRYLRHGKLIIDKNVSIEGVLEEAEFYNIASLIQIIREKMEAAK------ 124

  Fly   145 PLTRNDVIKAIIQTSVITELRFQGVNL-----SGADLRKLD-FRNINFKYANMSHCNLSHTNLNY 203
                   :..:.|..|...|:.|...|     |.:|..|.: ..|:...|     |..:.....:
Frog   125 -------VSQLQQKHVYRVLQCQEAELAQMVSSMSDSWKFEQLVNVGSPY-----CYSTEGQAEF 177

  Fly   204 CCLERADLQYANLECAQLVSVRGLCANMEGANLRGCNFED 243
            .|:...:||.....|    ..|.:|    ..::..|:.|:
Frog   178 LCVVSRELQTQPKSC----DGRTMC----NEHVPSCDTEE 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14647	NP_649465.6	BTB	35..138	CDD:197585	51/102 (50%)
		BTB	36..126	CDD:295341	47/89 (53%)
		Pentapeptide_4	160..241	CDD:290330	17/86 (20%)
		Pentapeptide	166..202	CDD:279183	8/41 (20%)
		Pentapeptide	204..243	CDD:279183	7/38 (18%)
		Pentapeptide_4	248..321	CDD:290330
		Pentapeptide	249..287	CDD:279183
		Pentapeptide	284..322	CDD:279183
kctd17	XP_004913948.1	BTB_POZ_KCTD2-like	24..107	CDD:349671	46/85 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D545341at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920