Protein Alignment CG9855 and MARCHF5

DIOPT Version :10

• Sequence 1: NP_649463.2
• Gene: CG9855 / 40556
• FlyBaseID: FBgn0037242
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_060294.1
• Gene: MARCHF5 / 54708
• HGNCID: 26025
• Length: 278
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 147/276 - (53%)
• Similarity: 202/276 - (73%)
• Gaps: 15/276 - (5%)

  Fly    62 ERCCWICFATDEDNRLAAWVKPCQCRGTTKWVHQSCLYRWIDEKTQKGNALRTVSCPQCQTEYII 126
            :|.||:|||||||:|.|.||:||:|||:||||||:||.||:||| |:||:...|:||||..||:|
Human    11 DRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEK-QRGNSTARVACPQCNAEYLI 74

  Fly   127 VFPQMGKLGGALEAIDNLIKRLSPFLAAGFFVGSLYWTAVTYGAVTFLQIVGHEHGMSIMESGDP 191
            |||::|.:...|:..|.||.:..||.|||..|||:|||||||||||.:|:|||:.|:.:||..||
Human    75 VFPKLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTAVTYGAVTVMQVVGHKEGLDVMERADP 139

  Fly   192 LVLLIGLPAIPVGLVLGRLIRWEDALLRLIR---NRGTVVRK-FPFVSLIYPNLSQEEEQQSISN 252
            |.||||||.|||.|:||::|||||.:|||.|   |:..::.. ||.:....|.:..|      :|
Human   140 LFLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYSNKLQILNSIFPGIGCPVPRIPAE------AN 198

  Fly   253 PATPALSDPVSATRVFCGALLLPTISSIVGRILFDTVDNTLHRTLLGGLTFITVKGILKIYLKQK 317
            |    |:|.|||||:.||||:.|||::|||:::|.:|::.|.||:|||:.|:.:||..|:|.||:
Human   199 P----LADHVSATRILCGALVFPTIATIVGKLMFSSVNSNLQRTILGGIAFVAIKGAFKVYFKQQ 259

  Fly   318 QYGRRKKRRIVDYTEE 333
            ||.|:..|:|::|.|:
Human   260 QYLRQAHRKILNYPEQ 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9855	NP_649463.2	RING_CH-C4HC3_MARCH5	63..124	CDD:438361	40/60 (67%)
MARCHF5	NP_060294.1	RING_CH-C4HC3_MARCH5	12..72	CDD:438361	40/60 (67%)