Protein Alignment Sfxn1-3 and SFXN2

DIOPT Version :10

• Sequence 1: NP_649460.3
• Gene: Sfxn1-3 / 40552
• FlyBaseID: FBgn0037239
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: XP_024303560.1
• Gene: SFXN2 / 118980
• HGNCID: 16086
• Length: 340
• Species: Homo sapiens
• Alignment Length: 315
• Identity: 156/315 - (49%)
• Similarity: 213/315 - (67%)
• Gaps: 2/315 - (0%)

  Fly     8 NIDEPKYDQNSYLGRAKHFFLLTNPLNVLASASKLEEARQIVIKYRAGKDVPECKTIDDVWRAKY 72
            |||.|::||.::|||.|||..:|:|..|..|..:|:.|:.:|.|.|.|. ||....::.:..||.
Human    27 NIDAPRWDQRTFLGRVKHFLNITDPRTVFVSERELDWAKVMVEKSRMGV-VPPGTQVEQLLYAKK 90

  Fly    73 LYDSAFHPETGEKQIVIGRMAAQMPMNTIITGGMMAFYKSTPAVVFWQWFNQTFNAIVNYTNRSG 137
            ||||||||:||||..|||||:.|:|...||||.|:.||::.|||:||||.||:|||:||||||:.
Human    91 LYDSAFHPDTGEKMNVIGRMSFQLPGGMIITGFMLQFYRTMPAVIFWQWVNQSFNALVNYTNRNA 155

  Fly   138 TSPISQQQLVTSYCLATSGALVTALSLNHAVKNMNPLLGRLVPLVAVGAANCINIPCMRMQELRN 202
            .||.|.:|:..||..||:.|:.||:.:|...|...||:||.||..||.||||:|||.||.|||..
Human   156 ASPTSVRQMALSYFTATTTAVATAVGMNMLTKKAPPLVGRWVPFAAVAAANCVNIPMMRQQELIK 220

  Fly   203 GVTLFDEHSNEMGISKKAAVVGISTVILSRIAMAIPGMTLTPVLMNVLEKRGFLAKYPRSNAPIQ 267
            |:.:.|.:.||:|.|::||.:||:.|::|||.|:.|||.|.||:|..|||..|:.|....:||:|
Human   221 GICVKDRNENEIGHSRRAAAIGITQVVISRITMSAPGMILLPVIMERLEKLHFMQKVKVLHAPLQ 285

  Fly   268 TLFCGFVLIFATPLGCAFFKQRADIKVDSLESEVRDSIRKKRPELET-VWFNKGL 321
            .:..|..|||..|:.|..|.|:.::.|..||.:::|:|:.|..|||. |:|||||
Human   286 VMLSGCFLIFMVPVACGLFPQKCELPVSYLEPKLQDTIKAKYGELEPYVYFNKGL 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sfxn1-3	NP_649460.3	SFXNs	8..321	CDD:461063	154/313 (49%)
SFXN2	XP_024303560.1	SFXNs	27..340	CDD:461063	154/313 (49%)