DRSC/TRiP Functional Genomics Resources

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Protein Alignment hkb and KLF16

DIOPT Version :9

Sequence 1:NP_524221.1 Gene:hkb / 40549 FlyBaseID:FBgn0261434 Length:297 Species:Drosophila melanogaster
Sequence 2:NP_114124.1 Gene:KLF16 / 83855 HGNCID:16857 Length:252 Species:Homo sapiens


Alignment Length:211 Identity:70/211 - (33%)
Similarity:92/211 - (43%) Gaps:28/211 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    99 PHPVFSHPQSSPLDTHAAATASLA---------PPNQHAPFLSAASDLYYAAAAAAAAAASTPTA 154
            |.|..:.| ::.||..||...:.:         ||....|...||:..:..||:..|.....|.|
Human    30 PGPEGAGP-AAGLDVRAARREAASPGTPGPPPPPPAASGPGPGAAAAPHLLAASILADLRGGPGA 93

  Fly   155 VPGFGMDPFTMGLMEQEYARVMAEDAQLKALNSRKQRPKKFKC--PNCDVAFSNNGQLKGHIRIH 217
            .|| |..|.:........:...|..|...|      ..|..:|  |:|..|:..:..||.|:|.|
Human    94 APG-GASPASSSSAASSPSSGRAPGAAPSA------AAKSHRCPFPDCAKAYYKSSHLKSHLRTH 151

  Fly   218 TGERPFKCDVNTCGKTFTRNEELTRHKRIHTGLRPYPCSACGKKFGRRDHLKKHMKTH------- 275
            ||||||.||...|.|.|.|::||.||.|.|||.:.:.|..|.|:|.|.|||.||.:.|       
Human   152 TGERPFACDWQGCDKKFARSDELARHHRTHTGEKRFSCPLCSKRFTRSDHLAKHARRHPGFHPDL 216

  Fly   276 --MPQERQLGPSIFVP 289
              .|..|...||..:|
Human   217 LRRPGARSTSPSDSLP 232

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hkbNP_524221.1 COG5048 195..>261 CDD:227381 31/67 (46%)
zf-C2H2 195..217 CDD:278523 8/23 (35%)
C2H2 Zn finger 197..217 CDD:275368 8/21 (38%)
zf-H2C2_2 210..236 CDD:290200 16/25 (64%)
C2H2 Zn finger 225..247 CDD:275368 11/21 (52%)
zf-H2C2_2 239..264 CDD:290200 12/24 (50%)
C2H2 Zn finger 255..275 CDD:275368 10/19 (53%)
KLF16NP_114124.1 KLF16_N 2..>88 CDD:409237 15/58 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 25..74 11/44 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 90..128 10/44 (23%)
COG5048 125..>189 CDD:227381 30/63 (48%)
C2H2 Zn finger 132..151 CDD:275368 7/18 (39%)
C2H2 Zn finger 159..181 CDD:275368 11/21 (52%)
zf-C2H2 187..209 CDD:395048 10/21 (48%)
C2H2 Zn finger 189..209 CDD:275368 10/19 (53%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 204..252 8/29 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 101 1.000 Inparanoid score I4986
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.960

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