DRSC/TRiP Functional Genomics Resources

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Protein Alignment hkb and Sp2

DIOPT Version :9

Sequence 1:NP_524221.1 Gene:hkb / 40549 FlyBaseID:FBgn0261434 Length:297 Species:Drosophila melanogaster
Sequence 2:NP_084496.2 Gene:Sp2 / 78912 MGIID:1926162 Length:613 Species:Mus musculus


Alignment Length:320 Identity:91/320 - (28%)
Similarity:127/320 - (39%) Gaps:103/320 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 QAATSAAP------------RTVKQEPEAITIKTELASSSFGHDCDGDFSSA----SSSASSSSN 72
            |||::..|            :|.:..|..:.|:|.          .|:..:.    |..|::::.
Mouse   325 QAASATLPTVPQKPSQNFQIQTTEPTPTQVYIRTP----------SGEVQTVLVQDSPPATAATT 379

  Fly    73 SSKSCYEEALNHSSYTRTSTPLLDAAPHPVFSHPQSSPLDTHAAATASLAPPNQHAPFLSAASDL 137
            |:.:|...||.              |||      .|.....|:||......|   .|.::.|..:
Mouse   380 STVTCNSPALR--------------APH------LSGTSKKHSAAILRKERP---LPKIAPAGSI 421

  Fly   138 YYAAAAAAAAAAS----------------------------TPTAVPG-----FGMDPFTMGL-M 168
            ....||..||||.                            |...|.|     .|:.|..:.| |
Mouse   422 ISLNAAQLAAAAQAMQTININGVQVQGVPVTITNTGGQQQLTVQNVSGNNLTISGLSPTQIQLQM 486

  Fly   169 EQ---------EYARVMA------EDAQLKALNSRKQRPKKFKC--PNCDVAFSNNGQLKGHIRI 216
            ||         |..|.||      :|.:.:   |.:|..||..|  |:|...|.....|:.|:|:
Mouse   487 EQALAGEAQPGEKRRRMACTCPNCKDGEKR---SGEQGKKKHVCHIPDCGKTFRKTSLLRAHVRL 548

  Fly   217 HTGERPFKCDVNTCGKTFTRNEELTRHKRIHTGLRPYPCSACGKKFGRRDHLKKHMKTHM 276
            |||||||.|:...|||.|||::||.||.|.|||.:.:.|:.|.|:|.|.|||.||.|||:
Mouse   549 HTGERPFVCNWFFCGKRFTRSDELQRHARTHTGDKRFECAQCQKRFMRSDHLTKHYKTHL 608

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hkbNP_524221.1 COG5048 195..>261 CDD:227381 31/67 (46%)
zf-C2H2 195..217 CDD:278523 7/23 (30%)
C2H2 Zn finger 197..217 CDD:275368 7/21 (33%)
zf-H2C2_2 210..236 CDD:290200 15/25 (60%)
C2H2 Zn finger 225..247 CDD:275368 12/21 (57%)
zf-H2C2_2 239..264 CDD:290200 12/24 (50%)
C2H2 Zn finger 255..275 CDD:275368 11/19 (58%)
Sp2NP_084496.2 zf-C2H2 525..549 CDD:278523 7/23 (30%)
C2H2 Zn finger 530..549 CDD:275368 6/18 (33%)
zf-H2C2_2 542..568 CDD:290200 15/25 (60%)
C2H2 Zn finger 557..579 CDD:275368 12/21 (57%)
zf-H2C2_2 571..594 CDD:290200 11/22 (50%)
zf-C2H2 585..607 CDD:278523 11/21 (52%)
C2H2 Zn finger 587..607 CDD:275368 11/19 (58%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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