DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment hkb and KLF13

DIOPT Version :9

Sequence 1:NP_524221.1 Gene:hkb / 40549 FlyBaseID:FBgn0261434 Length:297 Species:Drosophila melanogaster
Sequence 2:NP_057079.2 Gene:KLF13 / 51621 HGNCID:13672 Length:288 Species:Homo sapiens


Alignment Length:234 Identity:69/234 - (29%)
Similarity:92/234 - (39%) Gaps:61/234 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    97 AAPHPVFSHPQSSPLDTHAAATAS----------------------LAPPNQHAPFLSAASDLYY 139
            |..|.....|:|.|.....|||.:                      ||..||.||..:.|.....
Human    22 AVVHGPREGPESRPEGAAVAATPTLPRVEERRDGKDSASLFVVARILADLNQQAPAPAPAERREG 86

  Fly   140 AAA-------------------AAAAAAASTPTAV-----PGFGMDPFTMGLMEQEYARVMAEDA 180
            |||                   .|..|||:.|:..     |..|::|      |:|.....:.:.
Human    87 AAARKARTPCRLPPPAPEPTSPGAEGAAAAPPSPAWSEPEPEAGLEP------EREPGPAGSGEP 145

  Fly   181 QLKALNSR-------KQRPKKFKC--PNCDVAFSNNGQLKGHIRIHTGERPFKCDVNTCGKTFTR 236
            .|:....|       :...:|.||  ..|:..:..:..||.|:|.|||||||.|....|.|.|.|
Human   146 GLRQRVRRGRSRADLESPQRKHKCHYAGCEKVYGKSSHLKAHLRTHTGERPFACSWQDCNKKFAR 210

  Fly   237 NEELTRHKRIHTGLRPYPCSACGKKFGRRDHLKKHMKTH 275
            ::||.||.|.|||.:.:.|..|.|:|.|.|||.||.:.|
Human   211 SDELARHYRTHTGEKKFSCPICEKRFMRSDHLTKHARRH 249

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hkbNP_524221.1 COG5048 195..>261 CDD:227381 29/67 (43%)
zf-C2H2 195..217 CDD:278523 7/23 (30%)
C2H2 Zn finger 197..217 CDD:275368 6/21 (29%)
zf-H2C2_2 210..236 CDD:290200 15/25 (60%)
C2H2 Zn finger 225..247 CDD:275368 10/21 (48%)
zf-H2C2_2 239..264 CDD:290200 12/24 (50%)
C2H2 Zn finger 255..275 CDD:275368 10/19 (53%)
KLF13NP_057079.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 23..57 7/33 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 71..166 20/100 (20%)
COG5048 <162..252 CDD:227381 39/88 (44%)
zf-C2H2 167..191 CDD:278523 7/23 (30%)
C2H2 Zn finger 169..191 CDD:275368 6/21 (29%)
zf-H2C2_2 183..210 CDD:290200 15/26 (58%)
C2H2 Zn finger 199..221 CDD:275368 10/21 (48%)
zf-H2C2_2 213..236 CDD:290200 11/22 (50%)
zf-C2H2 227..249 CDD:278523 10/21 (48%)
C2H2 Zn finger 229..249 CDD:275368 10/19 (53%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 249..288 1/1 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 101 1.000 Inparanoid score I4986
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.960

Return to query results.
Submit another query.