DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hkb and Spps

DIOPT Version :9

Sequence 1:	NP_524221.1	Gene:	hkb / 40549	FlyBaseID:	FBgn0261434	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_001262902.1	Gene:	Spps / 42882	FlyBaseID:	FBgn0039169	Length:	985	Species:	Drosophila melanogaster

Alignment Length:	307	Identity:	85/307 - (27%)
Similarity:	117/307 - (38%)	Gaps:	65/307 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSTINLHPPQTYSRLFRPWDTQRQAATSAAPRTVKQEPEAITIKTELASSSFGHDCDGDFSSASS 65
            :::|...||.|:..:..   |....|.::.|.|...:.:.|         .|.|......||.|.
  Fly   549 ITSIKQEPPDTFGPISA---TGNPPAPASTPNTASPQQQQI---------KFLHTESNSLSSLSI 601

  Fly    66 SASSSSNSSKSCYEEALNHSSYTRTSTPLLDAAPHPVFSHPQSSPLDTHAAATASLAPPNQHAPF 130
            .||....        ||...:   |:||...|...|:   |.|.|..:...|..:.:.....||.
  Fly   602 PASIQIT--------ALPQQA---TNTPNTPATTQPI---PVSLPARSKVNAVTTSSTQITIAPT 652

  Fly   131 LSAASDLYYAAAAAAAAAASTPTAVPGFGMDPFTMGLMEQEYARVMAEDAQL----------KAL 185
            ......:...|..|.|:..||.|:..       |:....|.:..:....|.:          .|.
  Fly   653 GGQVVSVTTQARGATASIRSTNTSTT-------TITTPSQSHLNMNISVASVGGAATGGGGGTAT 710

  Fly   186 NSRKQRPKKF--KCPN--------------------CDVAFSNNGQLKGHIRIHTGERPFKCDVN 228
            ...|.|.|:.  .|||                    |...:.....|:.|:|.|||||||.|...
  Fly   711 GEPKPRLKRVACTCPNCTDGEKHSDKKRQHICHITGCHKVYGKTSHLRAHLRWHTGERPFVCSWA 775

  Fly   229 TCGKTFTRNEELTRHKRIHTGLRPYPCSACGKKFGRRDHLKKHMKTH 275
            .|||.|||::||.||:|.|||.:.:.|..|.|||.|.|||.||:|||
  Fly   776 FCGKRFTRSDELQRHRRTHTGEKRFQCQECNKKFMRSDHLSKHIKTH 822

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hkb	NP_524221.1	COG5048	195..>261	CDD:227381	31/87 (36%)
		zf-C2H2	195..217	CDD:278523	7/43 (16%)
		C2H2 Zn finger	197..217	CDD:275368	7/39 (18%)
		zf-H2C2_2	210..236	CDD:290200	15/25 (60%)
		C2H2 Zn finger	225..247	CDD:275368	12/21 (57%)
		zf-H2C2_2	239..264	CDD:290200	13/24 (54%)
		C2H2 Zn finger	255..275	CDD:275368	12/19 (63%)
Spps	NP_001262902.1	COG5048	<725..827	CDD:227381	42/98 (43%)
		C2H2 Zn finger	742..764	CDD:275368	4/21 (19%)
		zf-H2C2_2	756..783	CDD:290200	15/26 (58%)
		C2H2 Zn finger	772..794	CDD:275368	12/21 (57%)
		zf-H2C2_2	786..809	CDD:290200	11/22 (50%)
		zf-C2H2	800..822	CDD:278523	12/21 (57%)
		C2H2 Zn finger	802..822	CDD:275368	12/19 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010