DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment hkb and Sp9

DIOPT Version :9

Sequence 1:NP_524221.1 Gene:hkb / 40549 FlyBaseID:FBgn0261434 Length:297 Species:Drosophila melanogaster
Sequence 2:NP_001005343.1 Gene:Sp9 / 381373 MGIID:3574660 Length:484 Species:Mus musculus


Alignment Length:291 Identity:91/291 - (31%)
Similarity:122/291 - (41%) Gaps:42/291 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 LHPPQTYSRLFRPWDTQRQAATSAAPRTVKQEPEAITIKTELASSSFG--HDCDGDFSSASSSAS 68
            |:|....:..:..|......:|.||...           |..|:||:.  |...|.:....:.|.
Mouse   145 LYPRVGMAHPYESWYKSGFHSTLAAGEV-----------TNGAASSWWDVHSSPGSWLEVQNPAG 198

  Fly    69 SSSNSSKSCYEEALNHSSYTRTSTPLLDAAPHPVFSHPQSSPLDTHAAATASLAPPNQH------ 127
            ...:|..|...:|..||. ..|..|...:..|..||   |:.|.:.|||.:.|...:||      
Mouse   199 GLQSSLHSGAPQASLHSQ-LGTYNPDFSSLTHSAFS---STGLGSSAAAASHLLSTSQHLLAQDG 259

  Fly   128 -APFLSAASDLYYAAAAAAAAAASTPTAVPGFGMDPFTMGLMEQEYARVMA----------EDAQ 181
             .|.|.:.||...|.|||||:|..:..|....|      |...:...|...          |..:
Mouse   260 FKPVLPSYSDSSAAVAAAAASAMISGAAAAAAG------GSSARSARRYSGRATCDCPNCQEAER 318

  Fly   182 LKALNSRKQRPKKFKC--PNCDVAFSNNGQLKGHIRIHTGERPFKCDVNTCGKTFTRNEELTRHK 244
            |....:..:|.....|  |.|...:.....||.|:|.|||||||.|:...|||.|||::||.||.
Mouse   319 LGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHL 383

  Fly   245 RIHTGLRPYPCSACGKKFGRRDHLKKHMKTH 275
            |.|||.:.:.|..|.|:|.|.|||.||:|||
Mouse   384 RTHTGEKRFACPVCNKRFMRSDHLSKHIKTH 414

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hkbNP_524221.1 COG5048 195..>261 CDD:227381 31/67 (46%)
zf-C2H2 195..217 CDD:278523 7/23 (30%)
C2H2 Zn finger 197..217 CDD:275368 7/21 (33%)
zf-H2C2_2 210..236 CDD:290200 16/25 (64%)
C2H2 Zn finger 225..247 CDD:275368 12/21 (57%)
zf-H2C2_2 239..264 CDD:290200 12/24 (50%)
C2H2 Zn finger 255..275 CDD:275368 11/19 (58%)
Sp9NP_001005343.1 SP9_N 19..333 CDD:411695 49/208 (24%)
9aaTAD, inactive. /evidence=ECO:0000250|UniProtKB:P0CG40 178..186 3/7 (43%)
C2H2 Zn finger 337..356 CDD:275368 6/18 (33%)
zf-H2C2_2 348..375 CDD:404364 16/26 (62%)
C2H2 Zn finger 364..386 CDD:275368 12/21 (57%)
zf-H2C2_2 378..401 CDD:404364 11/22 (50%)
zf-C2H2 392..414 CDD:395048 11/21 (52%)
C2H2 Zn finger 394..414 CDD:275368 11/19 (58%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 409..446 5/6 (83%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

Return to query results.
Submit another query.