DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hkb and Kr

DIOPT Version :9

Sequence 1:	NP_524221.1	Gene:	hkb / 40549	FlyBaseID:	FBgn0261434	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_001261181.1	Gene:	Kr / 38012	FlyBaseID:	FBgn0001325	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	278	Identity:	78/278 - (28%)
Similarity:	120/278 - (43%)	Gaps:	43/278 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 TQRQAATSAAPRTVKQEPEAITIKTELASSSFGHDCDGDFSSASSSASSSSNSSKSCYEEALNHS 85
            ||..||...|...:.|.|     .:.||::.|.|:....|.:.::..|.....:......|..||
  Fly    71 TQLLAANRQAAAFMAQLP-----MSTLANTLFPHNPAALFGAWAAQQSLPPQGTHLHSPPASPHS 130

  Fly    86 SYTRTSTPLLDAAPHPVFSHPQSSPLDTHAAATA-SLAPPNQHAPFLS-AASDLYYAAAA--AAA 146
            .   .||| |.:..||:.| |.|:|.....|..| .|:...:....:| :.:|:|:.:..  :..
  Fly   131 P---LSTP-LGSGKHPLNS-PNSTPQHHEPAKKARKLSVKKEFQTEISMSVNDMYHTSGGPISPP 190

  Fly   147 AAASTPTAV----------PGFGMDP-----FTMGLMEQEYARVMAEDAQLKALNSRKQR----P 192
            ::.|:|.:.          .|...||     ||..:..:.:.        .|.:....:|    .
  Fly   191 SSGSSPNSTHDGAGGNAGCVGVSKDPSRDKSFTCKICSRSFG--------YKHVLQNHERTHTGE 247

  Fly   193 KKFKCPNCDVAFSNNGQLKGHIRIHTGERPFKCDVNTCGKTFTRNEELTRHKRIHTGLRPYPCSA 257
            |.|:||.|...|:.:..||.|:|:||||:|:.|  :.|.:.|.:...|.||.|:|||.|||.|..
  Fly   248 KPFECPECHKRFTRDHHLKTHMRLHTGEKPYHC--SHCDRQFVQVANLRRHLRVHTGERPYTCEI 310

  Fly   258 CGKKFGRRDHLKKHMKTH 275
            |..||...:.||.||..|
  Fly   311 CDGKFSDSNQLKSHMLVH 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hkb	NP_524221.1	COG5048	195..>261	CDD:227381	29/65 (45%)
		zf-C2H2	195..217	CDD:278523	9/21 (43%)
		C2H2 Zn finger	197..217	CDD:275368	8/19 (42%)
		zf-H2C2_2	210..236	CDD:290200	12/25 (48%)
		C2H2 Zn finger	225..247	CDD:275368	7/21 (33%)
		zf-H2C2_2	239..264	CDD:290200	14/24 (58%)
		C2H2 Zn finger	255..275	CDD:275368	8/19 (42%)
Kr	NP_001261181.1	C2H2 Zn finger	224..244	CDD:275368	2/27 (7%)
		zf-H2C2_2	237..261	CDD:290200	7/23 (30%)
		C2H2 Zn finger	252..272	CDD:275368	8/19 (42%)
		zf-H2C2_2	264..289	CDD:290200	12/26 (46%)
		C2H2 Zn finger	280..300	CDD:275368	7/21 (33%)
		zf-H2C2_2	292..316	CDD:290200	13/23 (57%)
		C2H2 Zn finger	308..328	CDD:275368	8/19 (42%)
		zf-H2C2_2	321..345	CDD:290200	5/8 (63%)
		C2H2 Zn finger	336..352	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1809
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960