DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hkb and sug

DIOPT Version :9

Sequence 1:	NP_524221.1	Gene:	hkb / 40549	FlyBaseID:	FBgn0261434	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_610826.1	Gene:	sug / 36424	FlyBaseID:	FBgn0033782	Length:	384	Species:	Drosophila melanogaster

Alignment Length:	260	Identity:	64/260 - (24%)
Similarity:	97/260 - (37%)	Gaps:	74/260 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 PRTV-----KQEPEAITIKT-----ELASSSFGHDCDGDFSSASSSASSSSNSSKSCYEEALNHS 85
            ||.:     :|..:::.:|.     ||..|..      :|...|.|.||||... :..:...|.:
  Fly    76 PRPIAGYGYRQRTQSVIMKARGQQDELCRSPV------EFPDDSKSCSSSSECG-TASDFVCNWT 133

  Fly    86 SYTRTSTPLLDAAPHPVFSHPQSSPLDTHAAATASLAPPNQHAPFLSAASDLYYAAAAAAAAAAS 150
            ...|....|...|.|....|           |.|||            ...|||........:..
  Fly   134 DCDRVFDTLDALAQHVTQRH-----------AIASL------------TDGLYYCRWRGCQRSER 175

  Fly   151 TPTAVPGFGMDPFTMGLMEQEYARVMAEDAQLKAL----NSRKQRPKKFKCPNCDVAFSNNGQLK 211
                  ||                    :|:.|.|    ...|::|  .:|..|:.:||....||
  Fly   176 ------GF--------------------NARYKMLVHTRTHTKEKP--HRCHLCEKSFSRAENLK 212

  Fly   212 GHIRIHTGERPFKCDVNTCGKTFTRNEELTRHKRIHTGLRPYPC--SACGKKFGRRDHLKKHMKT 274
            .|||.|:||:|:||....|.|.::.:.:..:|.|.|:..:||.|  :.|.|::.....|:||:||
  Fly   213 IHIRSHSGEKPYKCSFEGCQKAYSNSSDRFKHTRTHSMEKPYMCKVAGCQKRYTDPSSLRKHVKT 277

Fly 275 274
Fly 278 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hkb	NP_524221.1	COG5048	195..>261	CDD:227381	24/67 (36%)
		zf-C2H2	195..217	CDD:278523	9/21 (43%)
		C2H2 Zn finger	197..217	CDD:275368	9/19 (47%)
		zf-H2C2_2	210..236	CDD:290200	13/25 (52%)
		C2H2 Zn finger	225..247	CDD:275368	5/21 (24%)
		zf-H2C2_2	239..264	CDD:290200	8/26 (31%)
		C2H2 Zn finger	255..275	CDD:275368	8/22 (36%)
sug	NP_610826.1	C2H2 Zn finger	170..190	CDD:275368	5/45 (11%)
		zf-H2C2_2	183..207	CDD:290200	6/25 (24%)
		COG5048	192..>271	CDD:227381	27/80 (34%)
		C2H2 Zn finger	198..218	CDD:275368	9/19 (47%)
		zf-H2C2_2	210..237	CDD:290200	13/26 (50%)
		C2H2 Zn finger	226..248	CDD:275368	5/21 (24%)
		C2H2 Zn finger	256..277	CDD:275368	6/20 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1809
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050