DRSC/TRiP Functional Genomics Resources

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Protein Alignment hkb and Sp6

DIOPT Version :9

Sequence 1:NP_524221.1 Gene:hkb / 40549 FlyBaseID:FBgn0261434 Length:297 Species:Drosophila melanogaster
Sequence 2:NP_001102303.1 Gene:Sp6 / 363672 RGDID:1306768 Length:376 Species:Rattus norvegicus


Alignment Length:363 Identity:91/363 - (25%)
Similarity:125/363 - (34%) Gaps:141/363 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 INLHPPQTYSRLFRPWDTQRQAATSAAPRTVKQEPEAITIKT-----ELASSSFGHDCDGDFSSA 63
            ::|.|.|||           |..||         |||....:     ||.|...|.:.  |||..
  Rat    24 LDLQPLQTY-----------QGHTS---------PEAGDYPSPLQPGELQSLPLGPEV--DFSQG 66

  Fly    64 SSSASSSSNSSKSCYEEALNHSSYTRTSTPLLDAAPHPVFS------------------------ 104
            .....:||.  .:|.:        ..:.:||   ||.| ||                        
  Rat    67 YELPGASSR--VTCED--------LESDSPL---APGP-FSKLLQPDMSHHYESWFRPTHPGTED 117

  Fly   105 ------HPQSSPLD---THAAATA--------------------SLAPPNQHAPFLSAASDLYYA 140
                  ||.:|.:|   |..|.|:                    ...||:.|...|..|:...:.
  Rat   118 GSWWDLHPGTSWMDLPHTQGALTSPGHPGALQPALGGYVGDHQLCAPPPHPHPHHLLPAAGGQHL 182

  Fly   141 AAAAAAAAASTPTAVPGFGMDPFTMGLMEQEYARVMAEDAQLKALNSRKQRPKK-----FKCPN- 199
            ......|......|....|:|              .:.||..:...||:..|:.     .:||| 
  Rat   183 LGPPDGAKVLEAAAPESQGLD--------------SSLDAAARPKGSRRSVPRSSGQTVCRCPNC 233

  Fly   200 ---------------------------CDVAFSNNGQLKGHIRIHTGERPFKCDVNTCGKTFTRN 237
                                       |..|::....||.|:|.|:|:|||.|:...|||.|||:
  Rat   234 LEAERLGAPCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRS 298

  Fly   238 EELTRHKRIHTGLRPYPCSACGKKFGRRDHLKKHMKTH 275
            :||.||.:.|||.:.:||:.|.:.|.|.|||.||||||
  Rat   299 DELQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTH 336

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hkbNP_524221.1 COG5048 195..>261 CDD:227381 31/93 (33%)
zf-C2H2 195..217 CDD:278523 9/49 (18%)
C2H2 Zn finger 197..217 CDD:275368 9/47 (19%)
zf-H2C2_2 210..236 CDD:290200 14/25 (56%)
C2H2 Zn finger 225..247 CDD:275368 11/21 (52%)
zf-H2C2_2 239..264 CDD:290200 11/24 (46%)
C2H2 Zn finger 255..275 CDD:275368 11/19 (58%)
Sp6NP_001102303.1 C2H2 Zn finger 259..278 CDD:275368 6/18 (33%)
COG5048 <261..>336 CDD:227381 37/74 (50%)
zf-H2C2_2 270..297 CDD:290200 14/26 (54%)
C2H2 Zn finger 286..308 CDD:275368 11/21 (52%)
zf-H2C2_2 300..323 CDD:290200 10/22 (45%)
zf-C2H2 314..336 CDD:278523 12/21 (57%)
C2H2 Zn finger 316..336 CDD:275368 11/19 (58%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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