DRSC/TRiP Functional Genomics Resources

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Protein Alignment hkb and sp3b

DIOPT Version :9

Sequence 1:NP_524221.1 Gene:hkb / 40549 FlyBaseID:FBgn0261434 Length:297 Species:Drosophila melanogaster
Sequence 2:XP_005165855.1 Gene:sp3b / 322961 ZFINID:ZDB-GENE-110815-3 Length:783 Species:Danio rerio


Alignment Length:376 Identity:88/376 - (23%)
Similarity:126/376 - (33%) Gaps:152/376 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    40 AITIKTELASSSFGHDCDGDFSSASSSASSSSNSSKS--CYEEALN------------HSSYTRT 90
            |.||.|.:.:       ||.......:.::|.|..:|  | .|:||            .:|.|.|
Zfish   355 AQTIATSVTA-------DGQLIMTGPTTTTSDNQGESGKC-TESLNANDANANAFVPTTTSSTST 411

  Fly    91 STP-LLD-----------AAPHPVFSHPQSS------------PLDTHAAATASLAPPNQHAPFL 131
            |.| .:|           :|.|...|:.|.:            |..|...|..:|    |....|
Zfish   412 SLPETIDGTGVLTQATAVSAGHQDLSYIQQNHTTGGEQVVQLLPAQTADGAAQTL----QSVQLL 472

  Fly   132 SAASDLYYAAAAA------------------------AAAAASTP--TAVP-------------G 157
            :|.:.|..|...:                        ||...|:|  |..|             .
Zfish   473 NAGTFLIQAQTVSPTGQIQWQTFQVQGVQNLQNLQLPAAGGVSSPQITLAPVQTLSLGQSGTTGA 537

  Fly   158 FGMDP-------FTMGLMEQE---------------------------------YARVMAEDAQL 182
            .|..|       .::|..:|:                                 ..|::.||.:.
Zfish   538 LGQIPNLQTVTVNSVGQYQQDENTESHTDIQIKEEPESDDWPNSTLSTSDLAHLRVRLVEEDMEG 602

  Fly   183 KALNSRKQRPKKFKCPNCDVA-----------------------FSNNGQLKGHIRIHTGERPFK 224
            .....::.|.....||||..|                       :.....|:.|:|.|:|||||.
Zfish   603 TGQEGKRLRRVACTCPNCKEAGGRGSSMGKKKQHICHIPGCGKVYGKTSHLRAHLRWHSGERPFI 667

  Fly   225 CDVNTCGKTFTRNEELTRHKRIHTGLRPYPCSACGKKFGRRDHLKKHMKTH 275
            |..:.|||.|||::||.||:|.|||.:.:.|..|.|:|.|.|||.||:|||
Zfish   668 CSWSYCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSDHLAKHIKTH 718

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hkbNP_524221.1 COG5048 195..>261 CDD:227381 31/88 (35%)
zf-C2H2 195..217 CDD:278523 8/44 (18%)
C2H2 Zn finger 197..217 CDD:275368 8/42 (19%)
zf-H2C2_2 210..236 CDD:290200 14/25 (56%)
C2H2 Zn finger 225..247 CDD:275368 12/21 (57%)
zf-H2C2_2 239..264 CDD:290200 12/24 (50%)
C2H2 Zn finger 255..275 CDD:275368 11/19 (58%)
sp3bXP_005165855.1 THAP 8..85 CDD:283206
C2H2 Zn finger 638..660 CDD:275368 3/21 (14%)
COG5048 <651..728 CDD:227381 37/68 (54%)
zf-C2H2 666..690 CDD:278523 13/23 (57%)
C2H2 Zn finger 668..690 CDD:275368 12/21 (57%)
zf-H2C2_2 682..705 CDD:290200 11/22 (50%)
zf-C2H2 696..718 CDD:278523 11/21 (52%)
C2H2 Zn finger 698..718 CDD:275368 11/19 (58%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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